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Tom van der Poll Selected Research

Fibrin

11/2014A short contemporary history of disseminated intravascular coagulation.
1/2014Evaluation of coagulation activation after rhinovirus infection in patients with asthma and healthy control subjects: an observational study.
2/2013Disseminated intravascular coagulation: a review for the internist.
7/2012Infection and inflammation as risk factors for thrombosis and atherosclerosis.
10/2011Nebulized anticoagulants limit coagulopathy but not inflammation in pseudomonas aeruginosa-induced pneumonia in rats.
1/2009Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats.
1/2008Tissue factor as an initiator of coagulation and inflammation in the lung.
1/2008Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats.
5/2007Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats.
11/2006Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1.
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Tom van der Poll Research Topics

Disease

98Infection
09/2015 - 02/2002
84Sepsis (Septicemia)
12/2015 - 06/2003
81Inflammation
12/2015 - 04/2002
78Pneumonia (Pneumonitis)
10/2015 - 01/2002
31Pneumococcal Pneumonia
07/2015 - 01/2002
23Endotoxemia
01/2013 - 04/2002
18Peritonitis
09/2013 - 10/2003
16Melioidosis
04/2014 - 06/2007
13Tuberculosis (Tuberculoses)
09/2015 - 01/2002
13Lung Injury
07/2014 - 10/2006
12Acute Lung Injury
04/2013 - 05/2003
10Human Influenza (Influenza)
01/2013 - 06/2004
8Hemorrhage
01/2015 - 08/2003
8Disseminated Intravascular Coagulation
11/2014 - 12/2002
7Critical Illness (Critically Ill)
01/2012 - 01/2004
6Fibrosis (Cirrhosis)
06/2015 - 03/2005
6Ischemia
01/2015 - 05/2004
6Bacterial Infections (Bacterial Infection)
01/2015 - 02/2006
6Necrosis
01/2015 - 11/2005
6Ventilator-Induced Lung Injury
12/2014 - 03/2009
6Hyperinsulinism (Hyperinsulinemia)
01/2011 - 06/2006
5Asthma (Bronchial Asthma)
10/2015 - 04/2012
5Malaria
08/2015 - 11/2004
5Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis)
06/2014 - 04/2003
5Hyperglycemia
01/2011 - 06/2006
4Adult Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
07/2015 - 05/2007
4Shock
04/2015 - 12/2005
4Meningitis
06/2014 - 04/2003
4Thrombosis (Thrombus)
07/2013 - 01/2007
4Acute-Phase Reaction
12/2012 - 01/2006
4Bacterial Pneumonia
10/2011 - 03/2004
4Pancreatitis
08/2008 - 10/2004
4Respiratory Tract Infections (Respiratory Tract Infection)
07/2008 - 10/2003
3Pulmonary Fibrosis (Hamman Rich Syndrome)
11/2015 - 02/2014
3Stroke (Strokes)
04/2015 - 01/2014
3Lyme Disease (Disease, Lyme)
08/2011 - 02/2008

Drug/Important Bio-Agent (IBA)

31Protein CIBA
11/2015 - 06/2003
25ThrombinFDA Link
10/2015 - 05/2002
25CytokinesIBA
08/2015 - 01/2002
20Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2014 - 05/2002
17FibrinIBA
11/2014 - 12/2002
15Interleukin-6 (Interleukin 6)IBA
03/2015 - 01/2002
15Toll-Like Receptors (Toll-Like Receptor)IBA
01/2015 - 12/2004
14Thromboplastin (Tissue Factor)IBA
07/2015 - 06/2004
13Messenger RNA (mRNA)IBA
01/2012 - 05/2003
11Advanced Glycosylation End ProductsIBA
09/2015 - 03/2009
11Plasminogen Activators (Plasminogen Activator)IBA
07/2015 - 06/2006
11ChemokinesIBA
08/2014 - 01/2002
10Toll-Like Receptor 4IBA
04/2015 - 08/2002
10AnticoagulantsIBA
01/2015 - 05/2003
10lipoteichoic acidIBA
11/2014 - 05/2002
9Proteins (Proteins, Gene)IBA
03/2015 - 04/2003
9Interleukin-18 (Interleukin 18)IBA
01/2014 - 01/2002
8Dacarbazine (DIC)FDA LinkGeneric
11/2014 - 12/2002
8Toll-Like Receptor 2IBA
07/2014 - 03/2004
7Carbon MonoxideIBA
08/2015 - 01/2004
7Anti-Bacterial Agents (Antibiotics)IBA
05/2015 - 04/2006
7Peroxidase (Myeloperoxidase)IBA
01/2014 - 08/2002
6Peptide Hydrolases (Proteases)IBA
10/2015 - 01/2004
6advanced glycosylation end-product receptorIBA
09/2015 - 05/2007
6Nucleosomes (Nucleosome)IBA
09/2015 - 01/2011
6Complement System Proteins (Complement)IBA
08/2015 - 07/2007
6Ceftriaxone (Ceftriaxon)FDA LinkGeneric
04/2015 - 07/2003
6Interleukin-1 (Interleukin 1)IBA
01/2014 - 02/2002
6platelet activating factor receptorIBA
06/2012 - 08/2003
6Fibrin Fibrinogen Degradation ProductsIBA
10/2011 - 01/2009
5Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
07/2015 - 02/2006
5Blood Coagulation Factors (Coagulation Factor)IBA
11/2014 - 08/2003
5Immunoglobulin M (IgM)IBA
07/2014 - 10/2005
5Phosphotransferases (Kinase)IBA
04/2014 - 07/2009
5ThrombomodulinIBA
04/2014 - 10/2005
5Protein Kinases (Protein Kinase)IBA
04/2013 - 04/2002
5Interleukin-10 (Interleukin 10)IBA
01/2013 - 04/2003
5Insulin (Novolin)FDA Link
01/2011 - 06/2006
5Interferon-gamma (Interferon, gamma)IBA
09/2009 - 11/2004
5InterleukinsIBA
02/2007 - 02/2002
5lipopolysaccharide-binding proteinIBA
03/2006 - 12/2003
4HMGB1 Protein (HMG1)IBA
12/2014 - 12/2007
4Biological Markers (Surrogate Marker)IBA
10/2014 - 03/2008
4FibrinolysinFDA Link
01/2014 - 03/2004
4Proteinase-Activated ReceptorsIBA
09/2012 - 03/2008
4Plasminogen Activator Inhibitor 1IBA
08/2012 - 12/2006
4Heparin (Liquaemin)FDA LinkGeneric
10/2011 - 11/2006
4Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
07/2011 - 12/2006
4salicylhydroxamic acid (SHAM)IBA
05/2009 - 02/2004
4Glucose (Dextrose)FDA LinkGeneric
02/2009 - 06/2006
4Prednisolone (Predate)FDA LinkGeneric
12/2008 - 02/2007
4Interleukin-12 (IL 12)IBA
06/2006 - 01/2002
3Bleomycin (Blenoxane)FDA LinkGeneric
11/2015 - 02/2014
3AllergensIBA
10/2015 - 03/2013
3Hydroxyproline (4 Hydroxyproline)IBA
06/2015 - 03/2005
3LigandsIBA
04/2014 - 06/2010
3LeptinIBA
02/2014 - 11/2005
3Tissue Plasminogen Activator (Alteplase)FDA Link
07/2012 - 07/2006
3danaproid (danaparoid)FDA Link
10/2011 - 01/2009

Therapy/Procedure

11Artificial Respiration (Mechanical Ventilation)
12/2014 - 10/2006
7Intraperitoneal Injections
06/2010 - 06/2004
6Ligation
04/2011 - 02/2004
4Critical Care
01/2012 - 01/2008
3Positive-Pressure Respiration (PEEP)
07/2014 - 10/2006