Wim B van den Berg Selected Research

Arthritis (Polyarthritis)

04/2008	Destructive Arthritis in the Absence of Both Fc{gamma}RI and Fc{gamma}RIII.
02/2008	Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: a comparative study using anti-TNFalpha, anti-IL-1alpha/beta and IL-1Ra.
02/2008	Cytokines and joint erosion in arthritis.
01/2008	T cell dependence of chronic destructive murine arthritis induced by repeated local activation of Toll-like receptor-driven pathways: crucial role of both interleukin-1beta and interleukin-17.
09/2007	Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis.
01/2007	Murine antigen-induced arthritis.
12/2006	Fcgamma receptors directly mediate cartilage, but not bone, destruction in murine antigen-induced arthritis: uncoupling of cartilage damage from bone erosion and joint inflammation.
10/2005	Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis.
01/2005	Local IL-13 gene transfer prior to immune-complex arthritis inhibits chondrocyte death and matrix-metalloproteinase-mediated cartilage matrix degradation despite enhanced joint inflammation.
01/2005	The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models.
06/2004	Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice.
08/2003	FcgammaRI up-regulation induced by local adenoviral-mediated interferon-gamma production aggravates chondrocyte death during immune complex-mediated arthritis.
05/2002	Local interleukin-12 gene transfer promotes conversion of an acute arthritis to a chronic destructive arthritis.

Articles by Research Topic

Disease

13	Arthritis (Polyarthritis) 04/2008 - 05/2002
8	Rheumatoid Arthritis 04/2008 - 01/2003
8	Inflammation 12/2006 - 12/2003
7	Experimental Arthritis 10/2005 - 01/2003
4	Osteoarthritis 01/2007 - 07/2002
2	Synovitis 09/2005 - 10/2003
2	Osteophyte 12/2003 - 07/2002
1	Neoplasms (Cancer) 09/2008
1	Shock 08/2008
1	Fibrosis (Cirrhosis) 01/2006
1	Disease Susceptibility (Diathesis) 03/2004
1	Infection 12/2003
1	Juvenile Rheumatoid Arthritis (Juvenile Idiopathic Arthritis) 06/2003
1	Tissue Adhesions 02/2003

Drug/Important Bio-Agent (IBA)

8	Interleukin-17 (Interleukin 27)IBA 08/2008 - 03/2003
3	Toll-Like Receptor 4IBA 04/2008 - 03/2004
3	Transforming Growth Factor beta (TGF-beta)IBA 01/2006 - 07/2002
3	Interleukin-1 (Interleukin 1)IBA 10/2005 - 03/2005
3	Interleukin-18 (Interleukin 18)IBA 09/2004 - 02/2003
2	CytokinesIBA 02/2008 - 01/2003
2	Interleukin-1beta (Interleukin 1 beta)IBA 01/2008 - 02/2003
2	AntigensIBA 01/2007 - 12/2006
2	NADPH Oxidase (NAD(P)H oxidase)IBA 02/2006 - 10/2003
2	Antigen-Antibody Complex (Immune Complex)IBA 01/2005 - 08/2003
2	Interleukin-12 (IL 12)IBA 12/2003 - 05/2002
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2003 - 02/2003
1	NF-kappa B (NF-kB)IBA 09/2008
1	Nuclear Pore Complex Proteins (Nucleoporins)IBA 09/2008
1	IgG Receptors (Fc gamma RI)IBA 04/2008
1	Collagen Type II (Type II Collagen)IBA 02/2008
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 02/2008
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2008
1	Matrix Metalloproteinase 3 (Stromelysin 1)IBA 01/2007
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 06/2006
1	Proteoglycans (Proteoglycan)IBA 02/2006
1	acetovanillone (apocynin)IBA 02/2006
1	Heme Oxygenase-1IBA 10/2005
1	Interleukin-17 ReceptorsIBA 10/2005
1	Matrix MetalloproteinasesIBA 10/2005
1	Interleukin-6 (Interleukin 6)IBA 01/2005
1	Interleukin-13IBA 01/2005
1	ZymosanIBA 06/2004
1	Toll-Like Receptor 2IBA 12/2003
1	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 12/2003
1	Myeloid Differentiation Factor 88IBA 12/2003
1	Proteins (Proteins, Gene)IBA 09/2003
1	Interferon-gamma (Interferon, gamma)IBA 08/2003
1	Oncostatin MIBA 06/2003
1	OsteoprotegerinIBA 03/2003
1	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 03/2003
1	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA 02/2003
1	C-Type Lectins (C-Type Lectin)IBA 02/2003