P C M van de Kerkhof Selected Research

Psoriasis (Pustulosis Palmaris et Plantaris)

09/2008	Analysis of 3-year national reimbursement application data on etanercept and efalizumab for psoriasis.
08/2008	Etanercept combined with methotrexate for high-need psoriasis.
05/2008	Psoriasis treatment with etanercept and efalizumab: clinical strategies influencing treatment outcome.
04/2008	Topical treatment of mild to moderate plaque psoriasis with 0.3% tacrolimus gel and 0.5% tacrolimus cream: the effect on SUM score, epidermal proliferation, keratinization, T-cell subsets and HLA-DR expression.
02/2008	A comparison of twice-daily calcipotriol ointment with once-daily short-contact dithranol cream therapy: quality-of-life outcomes of a randomized controlled trial of supervised treatment of psoriasis in a day-care setting.
02/2007	Explorative immunohistochemical study to evaluate the addition of a topical corticosteroid in the early phase of alefacept treatment for psoriasis.
02/2007	Oral retinoic acid metabolism blocking agent Rambazole for plaque psoriasis: an immunohistochemical study.
01/2007	Dermatologists' adherence to the guideline of the Dutch Society of Dermatology and Venereology with respect to the treatment with methotrexate for severe chronic plaque psoriasis: results from a Dutch survey.
10/2006	A comparison of twice-daily calcipotriol ointment with once-daily short-contact dithranol cream therapy: a randomized controlled trial of supervised treatment of psoriasis vulgaris in a day-care setting.
09/2006	Liver injury in long-term methotrexate treatment in psoriasis is relatively infrequent.
08/2006	A placebo-controlled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acid-photodynamic therapy in patients with psoriasis.
07/2006	Efficacy of the pulsed dye laser in the treatment of localized recalcitrant plaque psoriasis: a comparative study.
01/2006	Consistency of data in six phase III clinical studies of a two-compound product containing calcipotriol and betamethasone dipropionate ointment for the treatment of psoriasis.
06/2005	A global phase III randomized controlled trial of etanercept in psoriasis: safety, efficacy, and effect of dose reduction.
03/2005	Tacrolimus ointment for the treatment of severe facial plaque psoriasis.
03/2005	Dithranol irritation in psoriasis treatment: a study of 68 inpatients.
01/2005	A two-compound product containing calcipotriol and betamethasone dipropionate provides rapid, effective treatment of psoriasis vulgaris regardless of baseline disease severity.
09/2004	The impact of a two-compound product containing calcipotriol and betamethasone dipropionate (Daivobet/ Dovobet) on the quality of life in patients with psoriasis vulgaris: a randomized controlled trial.
02/2004	The effect of the combination of calcipotriol and betamethasone dipropionate versus both monotherapies on epidermal proliferation, keratinization and T-cell subsets in chronic plaque psoriasis.
01/2003	The effects of topical corticosteroids and a coal tar preparation on dithranol-induced irritation in patients with psoriasis.
11/2002	The response of uninvolved skin of patients with psoriasis to single and repeated applications of dithranol cream: an immunohistochemical assessment.
04/2002	Combining lesional short-contact dithranol therapy of psoriasis with a potent topical corticosteroid.
03/2002	Long-term efficacy and safety of tacalcitol ointment in patients with chronic plaque psoriasis.
03/2002	Flow cytometric assessment of clearance and relapse characteristics in psoriasis vulgaris after treatment with weekly clobetasol lotion under hydrocolloid occlusion versus twice-daily clobetasol ointment.

Articles by Research Topic

Disease

24	Psoriasis (Pustulosis Palmaris et Plantaris) 09/2008 - 03/2002
2	Vitiligo 01/2005 - 01/2002
1	Skin Diseases 07/2008
1	Keratosis 12/2007
1	Contact Dermatitis (Eczema, Contact) 04/2003

Drug/Important Bio-Agent (IBA)

6	calcipotriene (calcipotriol)FDA LinkGeneric 02/2008 - 02/2004
6	Anthralin (Dithranol)IBA 02/2008 - 04/2002
4	TNFR-Fc fusion protein (etanercept)FDA Link 09/2008 - 06/2005
4	betamethasone-17,21-dipropionate (betamethasone dipropionate)FDA LinkGeneric 01/2006 - 02/2004
3	Methotrexate (Mexate)FDA LinkGeneric 08/2008 - 09/2006
2	efalizumab FDA Link 09/2008 - 05/2008
2	Tacrolimus (Prograf)FDA Link 04/2008 - 03/2005
1	HLA-DR Antigens (HLA-DR)IBA 04/2008
1	imiquimod (Aldara)FDA Link 12/2007
1	R 115866IBA 02/2007
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 02/2007
1	alefacept (Amevive)FDA Link 02/2007
1	protoporphyrin IXIBA 08/2006
1	daivobet FDA Link 09/2004
1	cipamfyllineIBA 04/2003
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2003
1	Coal Tar (Estar)IBA 01/2003
1	Clobetasol (Clobetasol Propionate)FDA LinkGeneric 03/2002
1	1 alpha,24-dihydroxyvitamin D3 (Tacalcitol)IBA 03/2002
1	Colloids (Colloid)IBA 03/2002
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 01/2002
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2002

Therapy/Procedure

3	Aftercare (After-Treatment) 07/2008 - 03/2002
2	Day Care (Partial Hospitalization) 02/2008 - 10/2006
1	Transplants (Transplant) 12/2007
1	Photochemotherapy (Photodynamic Therapy) 08/2006
1	Dye Lasers 07/2006
1	Phototherapy (Light Therapy) 01/2005