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Aimery de Gramont Selected Research

Fluorouracil (Carac)

12/2012Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial.
12/2011Defective mismatch repair status as a prognostic biomarker of disease-free survival in stage III colon cancer patients treated with adjuvant FOLFOX chemotherapy.
7/2011Impact of young age on treatment efficacy and safety in advanced colorectal cancer: a pooled analysis of patients from nine first-line phase III chemotherapy trials.
4/2010Comparison of the levogyre and dextro-levogyre forms of leucovorin in a phase III trial of bimonthly LV5FU2 versus monthly 5-fluorouracil and high-dose leucovorin for patients with stage II and III colon cancer (GERCOR C96.1).
1/2010Association between disease-free survival and overall survival when survival is prolonged after recurrence in patients receiving cytotoxic adjuvant therapy for colon cancer: simulations based on the 20,800 patient ACCENT data set.
1/2010Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and FOLFOX response in colorectal cancer patients.
12/2009Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? The GERCOR OPTIMOX2 Study.
11/2007Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer.
8/2007Phase III study comparing a semimonthly with a monthly regimen of fluorouracil and leucovorin as adjuvant treatment for stage II and III colon cancer patients: final results of GERCOR C96.1.
8/2007Reintroduction of oxaliplatin is associated with improved survival in advanced colorectal cancer.
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Aimery de Gramont Research Topics

Disease

25Colorectal Neoplasms (Colorectal Cancer)
12/2012 - 04/2002
15Colonic Neoplasms (Colon Cancer)
12/2012 - 08/2003
10Neoplasms (Cancer)
03/2012 - 06/2003
3Neutropenia
12/2012 - 06/2004
3Pancreatic Neoplasms (Pancreatic Cancer)
08/2006 - 04/2002
2Carcinoma (Carcinomatosis)
12/2012 - 04/2002
2Microsatellite Instability
12/2011 - 01/2004
2Nausea
07/2011 - 11/2003
2Neoplasm Metastasis (Metastasis)
12/2009 - 01/2004
2Ovarian Neoplasms (Ovarian Cancer)
01/2005 - 11/2003
1Hypertension (High Blood Pressure)
12/2012
1Sarcoma (Soft Tissue Sarcoma)
03/2012
1Diarrhea
07/2011
1Fatty Liver
12/2009
1Breast Neoplasms (Breast Cancer)
01/2005
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2005
1Renal Cell Carcinoma (Grawitz Tumor)
01/2005
1Hemoptysis
01/2005
1Abdominal Pain (Pain, Abdominal)
11/2003
1Leukopenia
11/2003
1Vomiting
11/2003
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
04/2002
1Stomach Neoplasms (Stomach Cancer)
04/2002

Drug/Important Bio-Agent (IBA)

24Fluorouracil (Carac)FDA LinkGeneric
12/2012 - 04/2002
23oxaliplatin (Eloxatin)FDA LinkGeneric
12/2012 - 04/2002
17Leucovorin (Folinic Acid)FDA Link
12/2012 - 04/2002
11irinotecan (Camptosar)FDA LinkGeneric
03/2012 - 04/2002
6bevacizumabFDA Link
12/2012 - 01/2005
4cetuximab (Erbitux)FDA Link
10/2011 - 12/2006
4Epidermal Growth Factor Receptor (EGF Receptor)IBA
08/2011 - 05/2005
3capecitabine (Xeloda)FDA Link
12/2012 - 12/2006
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2011 - 07/2007
3gemcitabineFDA Link
08/2006 - 04/2002
2Monoclonal AntibodiesIBA
10/2011 - 08/2011
2Sodium Glutamate (Accent)IBA
01/2010 - 10/2007
2pemetrexed (MTA)FDA Link
11/2004 - 04/2002
2Folic Acid (Vitamin M)FDA LinkGeneric
11/2004 - 04/2002
2Cisplatin (Platino)FDA LinkGeneric
11/2003 - 04/2002
1XELOXIBA
12/2012
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
03/2012
1DNA (Deoxyribonucleic Acid)IBA
10/2011
1Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA
01/2010
1Asp(5)- oxytocin (OXA)IBA
01/2010
1chemotactic factor inactivatorIBA
12/2009
1Angiogenesis InhibitorsIBA
07/2007
1vatalanib (PTK787)IBA
07/2007
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
07/2007
1Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
11/2004
1N-methylsuccinimideIBA
01/2004
1Antineoplastic Agents (Antineoplastics)IBA
08/2003
1Hydroxyurea (Hydrea)FDA LinkGeneric
06/2003
1Dexamethasone (Maxidex)FDA LinkGeneric
04/2002
1AnthracyclinesIBA
04/2002

Therapy/Procedure

13Drug Therapy (Chemotherapy)
12/2012 - 04/2002
8Adjuvant Chemotherapy
12/2012 - 01/2004
3Heterologous Transplantation (Xenotransplantation)
10/2011 - 06/2003
1Salvage Therapy
03/2012
1Combination Drug Therapy (Combination Chemotherapy)
07/2011
1Cryotherapy (Therapy, Cold)
01/2004
1Laparotomy
11/2003
1Catheters
11/2003
1Premedication
04/2002