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Sophie de Brouwer Selected Research

Nifedipine (Adalat)

4/2010Gender differences in cardiac remodeling and clinical outcomes in chronic stable angina pectoris (from the ACTION Trial).
3/2008Quality management of a large randomized double-blind multi-centre trial: the ACTION experience.
11/2007Diagnostic criteria and adjudication process both determine published event-rates: the ACTION trial experience.
8/2007Predictive value of local and core laboratory echocardiographic assessment of cardiac function in patients with chronic stable angina: The ACTION study.
8/2007Uric acid and other renal function parameters in patients with stable angina pectoris participating in the ACTION trial: impact of nifedipine GITS (gastro-intestinal therapeutic system) and relation to outcome.
7/2007Resource utilization implications of treatment were able to be assessed from appropriately reported clinical trial data.
7/2007Blood pressure reduction in stable angina by nifedipine was related to stroke and heart failure reduction but not to coronary interventions.
3/2007The development of heart failure in patients with stable angina pectoris.
1/2007Tracking coronary calcification and atherosclerotic lesions in patients with stable angina pectoris undergoing nifedipine therapy.
2/2006Safety of nifedipine GITS in stable angina: the ACTION trial.
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Sophie de Brouwer Research Topics

Disease

6Heart Failure
05/2011 - 03/2005
5Angina Pectoris
05/2011 - 01/2007
5Stroke (Strokes)
05/2011 - 03/2005
4Coronary Disease (Coronary Heart Disease)
04/2010 - 08/2007
3Myocardial Infarction
05/2011 - 03/2005
3Coronary Artery Disease (Coronary Atherosclerosis)
01/2007 - 03/2005
2Transient Ischemic Attack
07/2007 - 03/2005
1Renal Insufficiency (Renal Failure)
08/2007
1Cardiovascular Diseases (Cardiovascular Disease)
03/2007
1Atherosclerotic Plaque (Atheroma)
01/2007
1Polyuria
02/2006
1Erectile Dysfunction
02/2006
1Skin Neoplasms (Skin Cancer)
02/2006
1Hypotension (Low Blood Pressure)
02/2006
1Melanoma (Melanoma, Malignant)
02/2006
1Asthenia
02/2006
1Constipation
02/2006
1Neoplasms (Cancer)
02/2006
1Muscle Cramp (Cramp)
02/2006
1Hypertension (High Blood Pressure)
03/2005

Drug/Important Bio-Agent (IBA)

11Nifedipine (Adalat)FDA LinkGeneric
04/2010 - 03/2005
3CalciumIBA
05/2011 - 01/2007
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
05/2011
1Vitamin KFDA Link
05/2011
1Angiotensin Receptor AntagonistsIBA
05/2011
1Uric Acid (Urate)IBA
08/2007
1AngiotensinsIBA
07/2007
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
07/2007
1CreatinineIBA
03/2007
1Glucose (Dextrose)FDA LinkGeneric
03/2007

Therapy/Procedure

1Orthopedic Procedures
07/2007