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Nava Zisapel Selected Research

Melatonin

3/2015Current Phase II investigational therapies for insomnia.
1/2015Prolonged release melatonin for improving sleep in totally blind subjects: a pilot placebo-controlled multicenter trial.
1/2015Lasting treatment effects in a postmarketing surveillance study of prolonged-release melatonin.
1/2014Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial.
9/2012Drugs for insomnia.
5/2012Effects of prolonged-release melatonin and zolpidem on postural stability in older adults.
4/2012Prolonged-release formulation of melatonin (Circadin) for the treatment of insomnia.
1/2012Efficacy and safety of prolonged-release melatonin for insomnia in middle-aged and elderly patients with hypertension: a combined analysis of controlled clinical trials.
7/2011Prolonged-release melatonin for children with neurodevelopmental disorders.
1/2011Prolonged release melatonin in the treatment of primary insomnia: evaluation of the age cut-off for short- and long-term response.
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Nava Zisapel Research Topics

Disease

19Sleep Initiation and Maintenance Disorders (Insomnia)
03/2015 - 12/2003
5Sleep Disorders
01/2015 - 01/2004
3Substance Withdrawal Syndrome (Withdrawal Symptoms)
01/2015 - 12/2007
3Hypertension (High Blood Pressure)
01/2012 - 10/2006
3Prostatic Neoplasms (Prostate Cancer)
07/2008 - 04/2002
3Carcinoma (Carcinomatosis)
03/2006 - 04/2002
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
03/2010 - 09/2009
2Fatigue
02/2009 - 05/2006
2Ganglion Cysts (Ganglion)
07/2008 - 07/2008
1Chronobiology Disorders (Circadian Rhythm Disorder)
03/2015
1Alzheimer Disease (Alzheimer's Disease)
01/2014
1Psychomotor Disorders
09/2012
1Anoxia (Hypoxia)
03/2010
1Glaucoma
07/2008
1Depressive Disorder (Melancholia)
07/2008
1Hepatocellular Carcinoma (Hepatoma)
07/2008
1Circadian Rhythm Sleep Disorders (Delayed Sleep Phase Syndrome)
07/2008
1Melanoma (Melanoma, Malignant)
07/2008
1Sleep Deprivation
05/2006
1Stroke (Strokes)
02/2002

Drug/Important Bio-Agent (IBA)

29MelatoninIBA
03/2015 - 02/2002
2Serotonin (5 Hydroxytryptamine)IBA
03/2015 - 09/2012
2orexins (orexin)IBA
03/2015 - 09/2012
2GABA-A Receptors (GABA(A) Receptor)IBA
01/2015 - 09/2012
2Malate Dehydrogenase (Dehydrogenase, Malate)IBA
03/2010 - 09/2009
2Retinaldehyde (Retinal)IBA
07/2008 - 07/2008
2Androgen Receptors (Androgen Receptor)IBA
05/2002 - 04/2002
2HormonesIBA
05/2002 - 04/2002
1tasimelteonIBA
03/2015
1Cholinesterase Inhibitors (Anticholinesterases)IBA
01/2014
1Memantine (Namenda)FDA Link
01/2014
1tebufenozide (Mimic)IBA
04/2012
1Hypnotics and Sedatives (Sedatives)IBA
04/2012
1Antihypertensive Agents (Antihypertensives)IBA
01/2012
1Glucose (Dextrose)FDA LinkGeneric
01/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2010
1Aspartic Acid (Aspartate)FDA Link
03/2010
1malic acid (malate)IBA
03/2010
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
07/2008
1Melatonin Receptors (Melatonin Receptor)IBA
07/2008
18-bromocyclic GMPIBA
03/2006
1Protein Kinase CIBA
03/2006
16-sulfatoxymelatoninIBA
01/2004
1Dihydrotestosterone (Androstanolone)IBA
05/2002
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
05/2002
1CreatinineIBA
02/2002

Therapy/Procedure

1Investigational Therapies (Experimental Therapy)
03/2015
1Drug Therapy (Chemotherapy)
09/2012