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Anas Younes Selected Research

N- (2- aminophenyl)- 4- ((4- pyridin- 3- ylpyrimidin- 2- ylamino)methyl)benzamide

6/2011Mocetinostat (MGCD0103): a review of an isotype-specific histone deacetylase inhibitor.
11/2010The class-I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6-independent mechanism.

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Anas Younes Research Topics

Disease

60Hodgkin Disease (Hodgkin's Disease)
02/2014 - 01/2002
42Neoplasms (Cancer)
04/2013 - 03/2002
37Lymphoma (Lymphomas)
12/2013 - 12/2002
25Non-Hodgkin Lymphoma (Lymphosarcoma)
12/2013 - 09/2003
11Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
07/2012 - 12/2003
7Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
08/2012 - 12/2003
6Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
05/2012 - 03/2003
5B-Cell Lymphoma (Lymphoma, B Cell)
08/2012 - 08/2003
5Disease Progression
07/2012 - 03/2004
5Necrosis
03/2011 - 08/2003
4Infection
12/2013 - 04/2005
3Neutropenia
12/2013 - 07/2005
3Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell)
12/2013 - 11/2010
3Hematologic Neoplasms (Hematological Malignancy)
11/2012 - 02/2008
3B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
02/2012 - 10/2004
3Leukemia
02/2012 - 10/2004
2Anemia
12/2013 - 07/2005
2Thrombocytopenia (Thrombopenia)
12/2013 - 11/2010
2Fatigue
12/2013 - 12/2013
2Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
07/2013 - 05/2012
2Testicular Neoplasms (Testicular Cancer)
11/2011 - 10/2011
2Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
11/2010 - 09/2010
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
08/2004 - 08/2004
1Dyspnea (Shortness of Breath)
12/2013
1Syncope (Fainting)
12/2013
1Pulmonary Embolism
12/2013

Drug/Important Bio-Agent (IBA)

15rituximab (Mabthera)FDA Link
12/2013 - 07/2003
10Doxorubicin (Adriamycin)FDA LinkGeneric
12/2013 - 12/2004
9cAC10-vcMMAEIBA
02/2014 - 11/2010
6fludarabineIBA
03/2012 - 12/2002
6Histone Deacetylase InhibitorsIBA
12/2011 - 09/2010
5LBH589IBA
12/2013 - 09/2010
5Bleomycin (Blenoxane)FDA LinkGeneric
12/2013 - 11/2006
5Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2013 - 12/2004
5Prednisone (Sone)FDA LinkGeneric
12/2013 - 12/2004
5Vincristine (Oncovin)FDA LinkGeneric
12/2013 - 12/2004
5vorinostat (suberoylanilide hydroxamic acid)FDA Link
07/2013 - 04/2008
5Monoclonal AntibodiesIBA
09/2012 - 08/2005
517-(allylamino)-17-demethoxygeldanamycin (17AAG)IBA
05/2012 - 04/2005
5bortezomib (Velcade)FDA Link
07/2011 - 05/2004
5Proteins (Proteins, Gene)IBA
11/2010 - 08/2003
5Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2007 - 04/2005
4Methotrexate (Mexate)FDA LinkGeneric
12/2013 - 12/2003
4Cytarabine (Cytosar-U)FDA LinkGeneric
12/2013 - 04/2005
4AntigensIBA
08/2012 - 01/2007
4Dacarbazine (DIC)FDA LinkGeneric
05/2012 - 11/2006
4Vinblastine (Vinblastine Sulfate)FDA Link
05/2012 - 11/2006
4CytokinesIBA
10/2011 - 01/2005
4Sirolimus (Rapamycin)FDA Link
11/2010 - 01/2006
4Proteasome Endopeptidase Complex (Proteasome)IBA
11/2010 - 05/2004
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2008 - 08/2003
4AntibodiesIBA
01/2007 - 08/2005
4Phosphotransferases (Kinase)IBA
02/2006 - 08/2003
3Dexamethasone (Maxidex)FDA LinkGeneric
12/2013 - 12/2002
3InterferonsIBA
05/2012 - 07/2005
3gemcitabineFDA Link
03/2012 - 02/2008
3Melphalan (Alkeran)FDA LinkGeneric
03/2012 - 04/2005
3temsirolimusFDA Link
11/2010 - 04/2008
3galiximabIBA
01/2007 - 03/2003
3NF-kappa B (NF-kB)IBA
05/2004 - 01/2002
2everolimusFDA Link
12/2013 - 04/2012
2Immunoconjugates (Immunoconjugate)IBA
08/2012 - 01/2007
2Adenosine Triphosphate (ATP)IBA
07/2012 - 01/2012
2A-factor (Streptomyces)IBA
07/2012 - 08/2003
2N 30IBA
10/2011 - 03/2002
2N- (2- aminophenyl)- 4- (N- (pyridin- 3- ylmethoxycarbonyl)aminomethyl)benzamide (MS 275)IBA
10/2011 - 09/2010
2Interleukin-12 (IL 12)IBA
10/2011 - 08/2004
2N- (2- aminophenyl)- 4- ((4- pyridin- 3- ylpyrimidin- 2- ylamino)methyl)benzamideIBA
06/2011 - 11/2010
2Interleukin-10 (Interleukin 10)IBA
03/2011 - 08/2008
2romidepsin (FK228)FDA Link
11/2010 - 09/2010
2Cyclin D1IBA
04/2008 - 10/2006
2Etoposide (VP 16)FDA LinkGeneric
12/2007 - 04/2005
2RANK LigandIBA
10/2007 - 09/2003
2VaccinesIBA
01/2007 - 08/2004
2anaplastic lymphoma kinaseIBA
12/2006 - 12/2003
2U 0126 (UO 126)IBA
12/2006 - 08/2003
2pegfilgrastim (Neulasta)FDA Link
11/2006 - 03/2006
2Paclitaxel (Taxol)FDA LinkGeneric
09/2006 - 03/2006
2TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
03/2006 - 09/2003
2TNF-Related Apoptosis-Inducing LigandIBA
03/2006 - 09/2003
2Caspase 8 (Caspase-8)IBA
08/2005 - 08/2003
2Mitoxantrone (Novantrone)FDA LinkGeneric
07/2005 - 12/2002
2LigandsIBA
10/2004 - 09/2003
2CD40 Ligand (CD40L)IBA
09/2003 - 01/2002
1DNA (Deoxyribonucleic Acid)IBA
10/2013
1Liposomes (Liposome)IBA
09/2013
1MicroRNAs (MicroRNA)IBA
08/2013
1BI 2536IBA
04/2013
1polo-like kinase 1IBA
04/2013
1Janus Kinase 2IBA
11/2012

Therapy/Procedure

25Drug Therapy (Chemotherapy)
12/2013 - 03/2002
17Stem Cell Transplantation
12/2013 - 12/2002
7Transplants (Transplant)
11/2013 - 02/2008
4Aftercare (After-Treatment)
12/2013 - 07/2005
3Radiotherapy
01/2003 - 03/2002
2Intravenous Infusions
08/2012 - 08/2005
2Homologous Transplantation (Allograft)
02/2008 - 12/2003
2Combination Drug Therapy (Combination Chemotherapy)
05/2007 - 09/2003
2Investigational Therapies (Experimental Therapy)
10/2005 - 08/2004
1Therapeutics
11/2013