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Weihai Ying Selected Research

NAD (NADH)

4/2015NAD+ treatment can prevent rotenone-induced increases in DNA damage, Bax levels and nuclear translocation of apoptosis-inducing factor in differentiated PC12 cells.
1/2015NAD⁺/NADH metabolism and NAD⁺-dependent enzymes in cell death and ischemic brain injury: current advances and therapeutic implications.
4/2014NAD(+) administration decreases doxorubicin-induced liver damage of mice by enhancing antioxidation capacity and decreasing DNA damage.
2/2014NAD(+) treatment prevents rotenone-induced apoptosis and necrosis of differentiated PC12 cells.
1/2013Roles of NAD (+) , PARP-1, and Sirtuins in Cell Death, Ischemic Brain Injury, and Synchrotron Radiation X-Ray-Induced Tissue Injury.
5/2012Prevention of traumatic brain injury-induced neuron death by intranasal delivery of nicotinamide adenine dinucleotide.
3/2012NAD(+) administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia.
2/2012NAD+ metabolism and NAD(+)-dependent enzymes: promising therapeutic targets for neurological diseases.
12/2011NAD+ treatment induces delayed autophagy in Neuro2a cells partially by increasing oxidative stress.
1/2011Oxidative stress and PARP activation mediate the NADH-induced decrease in glioma cell survival.
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Weihai Ying Research Topics

Disease

10Brain Injuries (Brain Injury)
04/2015 - 01/2007
8Ischemia
01/2013 - 07/2002
7Neoplasms (Cancer)
07/2014 - 01/2011
6Necrosis
04/2015 - 01/2011
5Inflammation
01/2015 - 04/2004
4Brain Ischemia (Cerebral Ischemia)
01/2015 - 01/2008
4Nervous System Diseases (Neurological Disorders)
01/2015 - 01/2014
4Glioma (Gliomas)
05/2014 - 01/2011
3Parkinson Disease (Parkinson's Disease)
01/2015 - 01/2011
2Wounds and Injuries (Trauma)
01/2015 - 01/2009
2Brain Edema (Cerebral Edema)
01/2013 - 03/2004
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2013 - 03/2012
2Stroke (Strokes)
02/2012 - 03/2004
1Huntington Disease (Huntington's Disease)
01/2015
1Craniocerebral Trauma (Head Injury)
01/2015
1Radiation Injuries (Radiation Sickness)
01/2013
1Edema
03/2012
1Alzheimer Disease (Alzheimer's Disease)
02/2012
1Brain Diseases (Brain Disorder)
01/2007
1Acidosis
03/2004

Drug/Important Bio-Agent (IBA)

12NAD (NADH)IBA
04/2015 - 01/2007
5Poly Adenosine Diphosphate RiboseIBA
02/2012 - 07/2002
3Adenosine Triphosphate (ATP)IBA
04/2015 - 06/2013
3Small Interfering RNA (siRNA)IBA
05/2014 - 01/2012
3CalciumIBA
02/2012 - 01/2008
2RotenoneIBA
04/2015 - 02/2014
2EnzymesIBA
01/2015 - 02/2012
2AntioxidantsIBA
04/2014 - 01/2011
2Annexin A5IBA
02/2014 - 01/2012
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2014 - 01/2011
2SirtuinsIBA
01/2013 - 02/2012
1DNA (Deoxyribonucleic Acid)IBA
04/2015
1Apoptosis Inducing FactorIBA
04/2015
1Sirtuin 2IBA
01/2015
1Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
05/2014
18-bromo-cyclic-ADP-riboseIBA
05/2014
1Doxorubicin (Adriamycin)FDA LinkGeneric
04/2014
1Dihydrotachysterol (AT 10)IBA
06/2013
11- (2,4- dichlorobenzyl)indazole- 3- carbohydrazide (adjudin)IBA
01/2013
1polylactic acid-polyglycolic acid copolymer (PLGA)IBA
05/2012
13-methyladenineIBA
03/2012
1Niacinamide (Nicotinamide)FDA LinkGeneric
02/2012
1Caspase 3 (Caspase-3)IBA
01/2012
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2011
16- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA
01/2011
1Oxidopamine (6 Hydroxydopamine)IBA
01/2011
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2011
1Simvastatin (Zocor)FDA LinkGeneric
01/2011
1N-Methylaspartate (NMDA)IBA
01/2011
1NADP (NADPH)IBA
01/2011
1NADPH Oxidase (NAD(P)H oxidase)IBA
01/2011
1Cysteine (L-Cysteine)FDA Link
01/2011
1Glutathione (Reduced Glutathione)IBA
03/2004
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2004
1Matrix MetalloproteinasesIBA
03/2004
1harpin (messenger)IBA
03/2004
1Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2004
1Glutamic Acid (Glutamate)FDA Link
03/2004
1ErythropoietinFDA Link
03/2004
1Nerve Growth Factors (Neurotrophins)IBA
03/2004
1Glucose (Dextrose)FDA LinkGeneric
09/2003
1aspartyl-glutamyl-valyl-aspartalIBA
09/2003
1Deoxyglucose (2 Deoxy D glucose)IBA
09/2003

Therapy/Procedure

4Synchrotrons
07/2014 - 01/2012
3Intranasal Administration
03/2012 - 01/2007
1Microspheres (Microsphere)
05/2012