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Derek M Yellon Selected Research

Myocardial Reperfusion Injury

5/2009Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.
3/2009The mitochondrial permeability transition pore as a target for preconditioning and postconditioning.
3/2005Atorvastatin and myocardial reperfusion injury: new pleiotropic effect implicating multiple prosurvival signaling.
9/2003Limitation of myocardial reperfusion injury by AMP579, an adenosine A1/A2A receptor agonist: role of A2A receptor and Erk1/2.

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Derek M Yellon Research Topics

Disease

43Reperfusion Injury
12/2015 - 10/2002
32Myocardial Infarction
01/2015 - 03/2003
27Ischemia
10/2015 - 08/2002
14Myocardial Ischemia (Ischemic Heart Diseases)
01/2016 - 01/2005
8Infarction
02/2013 - 10/2002
7Anoxia (Hypoxia)
07/2014 - 07/2005
4Obesity
05/2012 - 04/2009
4Myocardial Reperfusion Injury
05/2009 - 09/2003
4Contracture
05/2008 - 12/2003
3Acute Kidney Injury (Acute Renal Failure)
10/2015 - 12/2010
3Cardiovascular Diseases (Cardiovascular Disease)
01/2015 - 04/2009
3Necrosis
09/2011 - 10/2002
2Atherosclerosis
08/2013 - 09/2009
2Heart Failure
06/2013 - 11/2011
2Acidosis
08/2010 - 09/2007
2Body Weight (Weight, Body)
11/2009 - 01/2007
2Heart Diseases (Heart Disease)
01/2009 - 01/2007
1Insulin Resistance
11/2014
1Hypothermia
06/2013
1Acute Coronary Syndrome
03/2013
1Coronary Artery Disease (Coronary Atherosclerosis)
05/2012
1Hypertension (High Blood Pressure)
05/2012
1Stroke (Strokes)
05/2012
1Cardiomyopathies (Cardiomyopathy)
09/2011
1Metabolic Diseases (Metabolic Disease)
02/2011
1Type 2 Diabetes Mellitus (MODY)
01/2011
1Weight Gain
01/2011
1Weight Loss (Weight Reduction)
11/2009
1Flushing
09/2009

Drug/Important Bio-Agent (IBA)

20Phosphotransferases (Kinase)IBA
08/2012 - 02/2003
151- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
10/2014 - 08/2002
15mitochondrial permeability transition poreIBA
10/2014 - 12/2003
7Protein Kinases (Protein Kinase)IBA
08/2010 - 01/2005
6Insulin (Novolin)FDA Link
11/2014 - 04/2003
5Metformin (Glucophage)FDA LinkGeneric
01/2015 - 05/2008
5Cyclosporine (Ciclosporin)FDA LinkGeneric
06/2013 - 08/2002
5Glucagon-Like Peptide 1 (GLP 1)IBA
01/2013 - 01/2005
5Adenosine Triphosphate (ATP)IBA
09/2007 - 08/2002
570-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
08/2007 - 09/2003
4Glucose (Dextrose)FDA LinkGeneric
02/2013 - 11/2009
4atorvastatin (Lipitor)FDA Link
11/2011 - 02/2003
4ErythropoietinFDA Link
10/2011 - 12/2007
4Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
10/2010 - 02/2003
3Carbon MonoxideIBA
05/2012 - 02/2003
3Cell Surface ReceptorsIBA
07/2009 - 10/2003
3AdenosineFDA LinkGeneric
05/2009 - 09/2003
3Phosphatidylinositol 3-KinasesIBA
12/2007 - 03/2006
3Diazoxide (Hyperstat)FDA Link
08/2007 - 08/2002
3BradykininIBA
08/2007 - 02/2003
2Peptide Hormones (Polypeptide Hormones)IBA
02/2011 - 01/2009
2AdipokinesIBA
02/2011 - 12/2007
2LeptinIBA
10/2010 - 04/2009
2AutacoidsIBA
08/2010 - 10/2003
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2009 - 02/2003
2Purinergic P1 Receptors (Adenosine Receptor)IBA
05/2009 - 09/2003
2UrocortinsIBA
01/2009 - 10/2002
2U 0126 (UO 126)IBA
08/2008 - 09/2007
2apelin-13 peptideIBA
12/2007 - 11/2007
2sanglifehrin AIBA
08/2007 - 12/2003
1Biological Markers (Surrogate Marker)IBA
01/2016
1MicroRNAs (MicroRNA)IBA
01/2016
1NAADP (nicotinic acid adenine dinucleotide phosphate)IBA
12/2015
1Troponin T (T, Troponin)IBA
10/2015
1Insulin ReceptorIBA
11/2014
1Adrenergic Receptors (Adrenergic Receptor)IBA
07/2014
1Contrast MediaIBA
03/2014
1CXCR4 Receptors (CXCR4 Receptor)IBA
09/2013
1SmokeIBA
08/2013
1Mitochondrial DNA (mtDNA)IBA
08/2013
1exenatide (Byetta)FDA Link
06/2013
1Matrix MetalloproteinasesIBA
03/2013
1Blood Glucose (Blood Sugar)IBA
02/2013
1sitagliptin (Januvia)FDA Link
01/2013
1tranilast (N 5')IBA
01/2013
1vildagliptinIBA
01/2013
1Calmodulin (Calcium-Dependent Activator Protein)IBA
03/2012
1cyclophilin DIBA
11/2011
1A 769662IBA
06/2011
1ResistinIBA
03/2011
1LipidsIBA
01/2011
1GadoliniumIBA
01/2011
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
10/2010
1CytokinesIBA
08/2010
1Proteins (Proteins, Gene)IBA
05/2010
1Dynamins (Dynamin)IBA
05/2010
1AICA ribonucleotide (CAIR)IBA
02/2010
1AdiponectinIBA
11/2009
1Doxorubicin (Adriamycin)FDA LinkGeneric
11/2009
1CB1 Cannabinoid Receptor (CB1 Receptor)IBA
11/2009
1rimonabantIBA
11/2009
1Niacin (Nicotinic Acid)FDA LinkGeneric
09/2009
1Lipoproteins (Lipoprotein)IBA
09/2009

Therapy/Procedure

7Ischemic Postconditioning
01/2014 - 08/2004
3Transplants (Transplant)
10/2015 - 06/2010
3Coronary Artery Bypass (Coronary Artery Bypass Surgery)
10/2015 - 06/2010
2Angioplasty (Angioplasty, Transluminal)
09/2007 - 02/2005
2Lasers (Laser)
08/2004 - 12/2003
1Thrombolytic Therapy
06/2013
1Drug Therapy (Chemotherapy)
06/2012
1Transplantation (Transplant Recipients)
06/2010