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Kazuhiko Yanai Selected Research

Pyrilamine (Mepyramine)

6/2011Interaction of histamine and calcitonin gene-related peptide in the formalin induced pain perception in rats.
1/2007The physiological and pathophysiological roles of neuronal histamine: an insight from human positron emission tomography studies.
9/2003Effects of endogenous histamine on seizure development of pentylenetetrazole-induced kindling in rats.

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Kazuhiko Yanai Research Topics

Disease

24Alzheimer Disease (Alzheimer's Disease)
11/2014 - 11/2005
14Amyloid Plaque
09/2015 - 03/2004
7Pain (Aches)
11/2011 - 06/2002
6Dementia (Dementias)
01/2013 - 07/2009
6Seizures (Seizure)
01/2007 - 04/2003
3Rhinitis
03/2011 - 11/2003
3Schizophrenia (Dementia Praecox)
01/2007 - 08/2004
3Memory Disorders (Memory Loss)
03/2006 - 10/2002
2Tauopathies
11/2014 - 01/2014
2Disease Progression
11/2014 - 06/2014
2Sarcopenia
02/2014 - 12/2013
2Neoplasms (Cancer)
08/2013 - 11/2012
2Hypersensitivity (Allergy)
06/2013 - 06/2002
2Amyloidosis
01/2012 - 05/2010
2Fatigue
01/2012 - 11/2003
2Hyperalgesia
06/2011 - 01/2002
2Epilepsy (Aura)
03/2006 - 11/2004
1Normal Pressure Hydrocephalus
09/2015
1Weight Loss (Weight Reduction)
12/2013
1Bruxism
12/2013
1Temporomandibular Joint Disorders (Temporomandibular Joint Disorder)
12/2013
1Diabetes Mellitus
01/2013
1Parkinson Disease (Parkinson's Disease)
01/2012
1Neck Pain (Cervicalgia)
11/2011
1Back Pain (Backache)
11/2011
1Sleep Initiation and Maintenance Disorders (Insomnia)
07/2011
1Cough
07/2011
1Acquired Immunodeficiency Syndrome (AIDS)
12/2010
1Multiple System Atrophy
06/2010
1Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
05/2010
1Sleep Deprivation
01/2010
1Proteostasis Deficiencies
11/2009
1Anorexia Nervosa
02/2009
1Cataplexy
02/2009
1Narcolepsy
02/2009
1Psychotic Disorders (Schizoaffective Disorder)
09/2006
1Brain Injuries (Brain Injury)
09/2006
1Birth Injuries (Birth Injury)
09/2006

Drug/Important Bio-Agent (IBA)

21Amyloid (Amyloid Fibrils)IBA
09/2015 - 01/2007
18Histamine (Histamine Dihydrochloride)FDA Link
12/2013 - 01/2002
72- (2- (2- dimethylaminothiazol- 5- yl)ethenyl)- 6- (2- (fluoro)ethoxy)benzoxazoleIBA
08/2013 - 04/2007
6donepezil (Aricept)FDA LinkGeneric
04/2012 - 10/2002
6Histamine H1 Receptors (Histamine H1 Receptor)IBA
01/2012 - 11/2005
6Pentylenetetrazole (Metrazol)IBA
03/2006 - 04/2003
5tau Proteins (tau Protein)IBA
11/2014 - 11/2005
5Histamine Antagonists (Antihistamines)IBA
07/2011 - 11/2003
3AcetylcholinesteraseIBA
01/2012 - 10/2002
3Pyrilamine (Mepyramine)FDA Link
06/2011 - 09/2003
3orexins (orexin)IBA
01/2010 - 11/2005
3Dopamine (Intropin)FDA LinkGeneric
01/2007 - 08/2004
2benzimidazoleIBA
02/2014 - 11/2005
2SynucleinsIBA
01/2014 - 11/2009
2Histamine H1 AntagonistsIBA
12/2013 - 11/2003
2Glucose (Dextrose)FDA LinkGeneric
08/2013 - 11/2011
2alpha-SynucleinIBA
06/2010 - 09/2009
2thioperamideIBA
09/2009 - 03/2006
2Histamine H3 Receptors (Histamine H3 Receptor)IBA
09/2009 - 11/2004
2Doxepin (Mareen)FDA LinkGeneric
02/2009 - 01/2007
2Acetylcholine (Acetylcholine Chloride)FDA Link
01/2007 - 03/2006
2clobenpropitIBA
05/2004 - 09/2003
2Histidine DecarboxylaseIBA
06/2003 - 04/2003
1N- methyl- 2- (4'- methylaminophenyl)- 6- hydroxybenzothiazoleIBA
04/2014
12- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA
04/2014
1CoffeeFDA Link
02/2014
1royal jellyIBA
12/2013
1InterleukinsIBA
12/2013
1PlasticsIBA
12/2013
1HexokinaseIBA
08/2013
1AntibodiesIBA
11/2012
1Prealbumin (Transthyretin)IBA
01/2012
1calcitonin gene-related peptide (8-37)IBA
06/2011
1Ranitidine (Zantac)FDA LinkGeneric
06/2011
1Carbon MonoxideIBA
04/2011
1Loratadine (Alavert)FDA Link
03/2011
1Chlorpheniramine (Chlorphenamine)FDA LinkGeneric
03/2011
1RadiopharmaceuticalsIBA
12/2010
1Biological Markers (Surrogate Marker)IBA
06/2010
1LigandsIBA
11/2009
1Neurotransmitter Agents (Neurotransmitter)IBA
11/2009
1PrionsIBA
11/2009
1Amyloid beta-PeptidesIBA
10/2009
1amyloid beta-protein (1-42)IBA
09/2009
1Morphine (MS Contin)FDA LinkGeneric
09/2009
1GABA-A Receptors (GABA(A) Receptor)IBA
01/2007
1AdenosineFDA LinkGeneric
01/2007
1Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
01/2007
1Phosphotransferases (Kinase)IBA
09/2006
1GTP-Binding Proteins (G-Protein)IBA
09/2006
1Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
09/2006
1Dopamine D4 Receptors (Dopamine D4 Receptor)IBA
09/2006
1Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA
09/2006
1Street Drugs (Illicit Drugs)IBA
09/2006
1Dopamine beta-HydroxylaseIBA
09/2006
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
09/2006
1JNJ-5207852IBA
03/2006

Therapy/Procedure

1Cerebrospinal Fluid Shunts
09/2015
1Therapeutics
06/2014
1Analgesia
06/2013
1Spinal Manipulation
11/2011
1Denervation
01/2007