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S Yamagishi Selected Research

Nifedipine (Adalat)

11/2007Bay w 9798, a dihydropyridine structurally related to nifedipine with no calcium channel-blocking properties, inhibits tumour necrosis factor-alpha-induced vascular cell adhesion molecule-1 expression in endothelial cells by suppressing reactive oxygen species generation.
1/2007Revival of nifedipine, a dihydropyridine-based calcium blocker.
1/2007Nifedipine, a calcium-channel blocker, inhibits advanced glycation end-product-induced expression of monocyte chemoattractant protein-1 in human cultured mesangial cells.
1/2007Prevention of diabetic vascular calcification by nifedipine, a dihydropyridine-based calcium channel blocker.
1/2005Atheroprotective properties of nifedipine.
1/2005Potential therapeutic implication of nifedipine, a dihydropyridine-based calcium antagonist, in advanced glycation end product (AGE)-related disorders.
1/2004Nifedipine inhibits gene expression of receptor for advanced glycation end products (RAGE) in endothelial cells by suppressing reactive oxygen species generation.
1/2004Nifedipine inhibits tumor necrosis factor-alpha-induced leukocyte adhesion to endothelial cells by suppressing vascular cell adhesion molecule-1 (VCAM-1) expression.
1/2003Nifedipine inhibits apoptotic cell death of cultured endothelial cells induced by tumor necrosis factor-alpha.
1/2003Nifedipine inhibits tumor necrosis factor-alpha-induced monocyte chemoattractant protein-1 overexpression by blocking NADPH oxidase-mediated reactive oxygen species generation.

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S Yamagishi Research Topics

Disease

19Atherosclerosis
08/2011 - 01/2003
15Insulin Resistance
05/2015 - 01/2005
14Diabetic Retinopathy (Retinopathy, Diabetic)
01/2006 - 01/2002
12Diabetic Nephropathies (Diabetic Nephropathy)
08/2015 - 01/2001
12Hypertension (High Blood Pressure)
05/2015 - 01/2005
9Hyperglycemia
08/2015 - 01/2002
9Cardiovascular Diseases (Cardiovascular Disease)
05/2015 - 01/2004
9Diabetic Angiopathies (Diabetic Angiopathy)
01/2007 - 08/2000
8Inflammation
11/2008 - 07/2000
7Diabetes Mellitus
01/2007 - 01/2005
6Hepatocellular Carcinoma (Hepatoma)
05/2015 - 12/2006
6Neoplasm Metastasis (Metastasis)
08/2008 - 03/2003
5Melanoma (Melanoma, Malignant)
05/2013 - 01/2004
5Alzheimer Disease (Alzheimer's Disease)
01/2007 - 01/2004
4Obesity
05/2015 - 01/2005
4Liver Diseases (Liver Disease)
05/2015 - 01/2005
4Body Weight (Weight, Body)
04/2015 - 01/2002
4Neoplasms (Cancer)
05/2013 - 03/2003
3Fatty Liver
05/2015 - 01/2005
3Vascular System Injuries
09/2011 - 12/2006
3Coronary Artery Disease (Coronary Atherosclerosis)
01/2011 - 01/2006
3Neurodegenerative Diseases (Neurodegenerative Disease)
01/2007 - 01/2004
3Dehydration (Water Stress)
01/2007 - 01/2004
3Type 2 Diabetes Mellitus (MODY)
01/2005 - 01/2002
2Albuminuria
08/2015 - 07/2001
2Dyslipidemias (Dyslipidemia)
05/2015 - 01/2005
2Liver Cirrhosis (Hepatic Cirrhosis)
05/2015 - 01/2009
2Infection
01/2015 - 01/2009
2Pancreatic Neoplasms (Pancreatic Cancer)
05/2013 - 01/2005
2Uveitis
01/2008 - 11/2007
2Necrosis
11/2007 - 11/2006
2Rhinitis
03/2007 - 09/2000
2Osteoporosis
01/2006 - 01/2005
2Disease Progression
01/2005 - 01/2005
2Myocardial Infarction
01/2005 - 01/2005
1Fibrosis (Cirrhosis)
05/2015
1Hyperlipidemias (Hyperlipidemia)
05/2015
1Peritonitis
01/2015
1Breast Neoplasms (Breast Cancer)
05/2013
1Kidney Diseases (Kidney Disease)
01/2011
1Hypertriglyceridemia
09/2010
1Thrombosis (Thrombus)
03/2009

Drug/Important Bio-Agent (IBA)

39Advanced Glycosylation End ProductsIBA
08/2015 - 08/2000
12pigment epithelium-derived factorIBA
01/2011 - 01/2002
11Insulin (Novolin)FDA Link
04/2015 - 01/2002
10Nifedipine (Adalat)FDA LinkGeneric
11/2007 - 01/2003
8Glucose (Dextrose)FDA LinkGeneric
08/2015 - 01/2002
81,4-dihydropyridine (dihydropyridine)IBA
11/2007 - 01/2003
8CalciumIBA
11/2007 - 01/2003
7telmisartan (Micardis)FDA Link
03/2011 - 01/2005
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2009 - 01/2004
7Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2008 - 02/2003
6Proteins (Proteins, Gene)IBA
09/2008 - 01/2004
6Reactive Oxygen Species (Oxygen Radicals)IBA
11/2007 - 01/2003
6Retinaldehyde (Retinal)IBA
01/2005 - 01/2002
5Angiotensin IIIBA
12/2006 - 01/2003
4Metformin (Glucophage)FDA LinkGeneric
05/2013 - 01/2005
4GlyceraldehydeIBA
09/2008 - 01/2002
4PPAR gammaIBA
03/2008 - 01/2005
4CytokinesIBA
06/2007 - 01/2004
4azelnidipineIBA
11/2006 - 01/2005
4AcarboseFDA LinkGeneric
09/2006 - 01/2005
4alpha-Glucosidases (Acid Maltase)IBA
09/2006 - 01/2005
4CarbohydratesIBA
09/2006 - 01/2005
4PyridoxamineIBA
01/2006 - 01/2005
3atorvastatin (Lipitor)FDA Link
05/2015 - 01/2007
3FructoseIBA
04/2015 - 01/2005
3nateglinide (Starlix)FDA LinkGeneric
03/2011 - 12/2007
3N,N-dimethylarginine (asymmetric dimethylarginine)IBA
01/2008 - 01/2007
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
06/2007 - 01/2004
2Non-alcoholic Fatty Liver DiseaseIBA
05/2015 - 01/2009
2Blood Glucose (Blood Sugar)IBA
04/2015 - 01/2004
2DNA (Deoxyribonucleic Acid)IBA
04/2015 - 03/2003
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2013 - 01/2002
2CholesterolIBA
08/2011 - 01/2006
2Glycoproteins (Glycoprotein)IBA
03/2009 - 01/2005
2Serine (L-Serine)FDA Link
09/2008 - 03/2008
2Type 1 Angiotensin ReceptorIBA
03/2008 - 01/2006
2Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
11/2007 - 09/2000
2Calcium Channels (Calcium Channel)IBA
11/2007 - 11/2006
2polyolIBA
06/2007 - 04/2003
2Protein Kinase CIBA
06/2007 - 01/2004
2C-Reactive ProteinIBA
01/2007 - 12/2006
2Coenzyme A (CoA)IBA
01/2006 - 01/2006
2OxidoreductasesIBA
01/2006 - 01/2006
2YM 529IBA
01/2006 - 01/2005
1Carrier Proteins (Binding Protein)IBA
08/2015
18-hydroxy-2'-deoxyguanosineIBA
08/2015
1SodiumIBA
08/2015
1olmesartanIBA
06/2014
1AMP-Activated Protein KinasesIBA
05/2013
1sitagliptin (Januvia)FDA Link
09/2011
1rosuvastatin (Crestor)FDA Link
08/2011
1Adenosine Triphosphate (ATP)IBA
08/2011
1N-acetyltalosaminuronic acid (NAT)IBA
03/2011
1vildagliptinIBA
09/2010
1Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA
09/2010
1Branched-Chain Amino AcidsIBA
01/2009

Therapy/Procedure

1Catheters
01/2015
1Total Parenteral Nutrition
01/2015