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James N Weiss Selected Research

pamidronate (APD)

10/2015Small-Conductance Calcium-Activated Potassium Current Is Activated During Hypokalemia and Masks Short-Term Cardiac Memory Induced by Ventricular Pacing.
5/2015Targeting the late component of the cardiac L-type Ca2+ current to suppress early afterdepolarizations.
4/2011Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles.
9/2007Influence of channel subunit composition on L-type Ca2+ current kinetics and cardiac wave stability.
2/2005Dissociation of membrane potential and intracellular calcium during ventricular fibrillation.
12/2004Coexistence of two types of ventricular fibrillation during acute regional ischemia in rabbit ventricle.
5/2004Intracellular Ca dynamics in ventricular fibrillation.
7/2002Electrical refractory period restitution and spiral wave reentry in simulated cardiac tissue.
5/2002Action potential duration restitution and ventricular fibrillation due to rapid focal excitation.

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James N Weiss Research Topics

Disease

20Ventricular Fibrillation
10/2015 - 03/2002
11Ischemia
06/2015 - 03/2002
10Ventricular Tachycardia
10/2015 - 05/2002
7Cardiac Arrhythmias (Arrythmia)
03/2015 - 09/2006
6Heart Failure
02/2015 - 06/2009
5Hypokalemia
10/2015 - 08/2010
5Reperfusion Injury
06/2015 - 07/2003
4Heart Diseases (Heart Disease)
10/2015 - 09/2009
4Fibrosis (Cirrhosis)
09/2013 - 08/2008
4Cardiac Sudden Death (Sudden Cardiac Arrest)
08/2008 - 11/2003
3Atrial Fibrillation
09/2013 - 07/2002
2Neoplasms (Cancer)
06/2015 - 01/2015
2Myocardial Infarction
10/2013 - 05/2007
2Torsades de Pointes (Torsade de Pointes)
10/2013 - 04/2013
2Atrioventricular Block
10/2013 - 08/2006
2Bradycardia
07/2011 - 01/2010
2Myocardial Ischemia (Ischemic Heart Diseases)
12/2008 - 07/2003
2Anoxia (Hypoxia)
10/2008 - 03/2002
2Infarction
05/2007 - 03/2005
1Sudden Death
03/2015
1Ventricular Premature Complexes (Premature Ventricular Contraction)
10/2013
1Thrombosis (Thrombus)
09/2013
1Retinoblastoma (Glioblastoma, Retinal)
08/2011
1Necrosis
06/2005
1Long QT Syndrome
10/2004
1Rupture
08/2003

Drug/Important Bio-Agent (IBA)

17CalciumIBA
10/2015 - 10/2004
9pamidronate (APD)FDA LinkGeneric
10/2015 - 05/2002
6Reactive Oxygen Species (Oxygen Radicals)IBA
09/2013 - 08/2003
4ApaminIBA
10/2015 - 04/2013
4Cytochromes c (Cytochrome c)IBA
06/2005 - 03/2002
3Diazoxide (Hyperstat)FDA Link
06/2005 - 03/2002
2PotassiumIBA
10/2015 - 10/2013
2Sodium Channels (Sodium Channel)IBA
10/2015 - 03/2015
2SodiumIBA
03/2015 - 01/2011
2Connexin 43 (Connexin43)IBA
06/2012 - 07/2011
2Polymorphic catecholergic ventricular tachycardiaIBA
04/2011 - 09/2009
2Ion Channels (Ion Channel)IBA
08/2010 - 01/2010
2Isoproterenol (Isoprenaline)FDA LinkGeneric
02/2010 - 08/2006
2Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2008 - 03/2005
2Adenosine Triphosphate (ATP)IBA
06/2005 - 02/2005
2Gallopamil (D600)IBA
10/2004 - 10/2002
1Anti-Arrhythmia AgentsIBA
10/2015
1dofetilide (Tikosyn)FDA Link
10/2015
1KN 92IBA
10/2015
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
10/2015
1KN 93IBA
10/2015
1Calcium-Calmodulin-Dependent Protein KinasesIBA
10/2015
1EnzymesIBA
06/2015
1Glucose (Dextrose)FDA LinkGeneric
01/2015
1Protein Isoforms (Isoforms)IBA
01/2015
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
01/2015
1NADPH Oxidase (NAD(P)H oxidase)IBA
09/2013
1Angiotensin IIIBA
06/2012
1TyramineIBA
04/2012
1Carbon MonoxideIBA
02/2012
1HeterochromatinIBA
08/2011
1Proteins (Proteins, Gene)IBA
08/2011
1E2F Transcription FactorsIBA
08/2011
1heterochromatin-specific nonhistone chromosomal protein HP-1 (heterochromatin protein 1)IBA
08/2011
1SEA 0400IBA
07/2011
1Calcium-Activated Potassium Channels (Calcium-Activated Potassium Channel)IBA
04/2011
1Bidirectional tachycardiaIBA
04/2011
1ranolazineFDA Link
01/2011
1diazenedicarboxylic acid bis(N'-methylpiperazide)IBA
01/2011
1Methyl ester 1,4- dihydro- 2,6- dimethyl- 5- nitro- 4- (2- (trifluoromethyl)phenyl)- 3-Pyridinecarboxylic acidIBA
08/2010
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
08/2010
1salicylhydroxamic acid (SHAM)IBA
06/2009
1Creatine Kinase (Creatine Phosphokinase)IBA
12/2008
1Hydroxyl RadicalIBA
10/2008
1Glutathione (Reduced Glutathione)IBA
10/2008
1NAD (NADH)IBA
10/2008
1Transforming Growth Factor beta1 (TGF beta 1)IBA
08/2008
1Mitochondrial Proteins (Mitochondrial Protein)IBA
06/2008
1Propranolol (Inderal)FDA LinkGeneric
05/2007
1OxygenIBA
07/2005
1Adenosine Diphosphate (ADP)IBA
07/2005
1AntioxidantsIBA
06/2005
1AtractylosideIBA
03/2005
1Nitric Oxide DonorsIBA
03/2005
1ATP Translocases Mitochondrial ADPIBA
03/2005
1Pinacidil (Pindac)FDA Link
02/2005
1Fatty Acids (Saturated Fatty Acids)IBA
07/2003
1AconitineIBA
05/2002
1mitochondrial K(ATP) channelIBA
03/2002
1Amiodarone (Amiodarona)FDA LinkGeneric
03/2002

Therapy/Procedure

4Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
08/2008 - 11/2003
2Drug Therapy (Chemotherapy)
03/2015 - 11/2003
1Cryosurgery
10/2013
1Microelectrodes
06/2012
1Electrodes (Electrode)
10/2008