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Brian R Walker Selected Research

Obesity

04/200811-Beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors in type 2 diabetes mellitus and obesity.
07/2007Can cortisol predict the future in obesity?
05/2007Omental 11beta-hydroxysteroid dehydrogenase 1 correlates with fat cell size independently of obesity.
02/2006Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 in obesity.
03/2005Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone.
04/2004Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice.
02/200411 beta-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome.
01/200411beta-hydroxysteroid dehydrogenase type 1 in obesity.
08/2003Local and systemic impact of transcriptional up-regulation of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue in human obesity.
07/2003Obese Zucker rats have reduced mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type 1 expression in hippocampus-implications for dysregulation of the hypothalamic-pituitary-adrenal axis in obesity.

Articles by Research Topic

Disease

10Obesity
04/2008 - 07/2003
4Insulin Resistance
09/2006 - 05/2002
2Syndrome
05/2008 - 02/2004
2Cardiovascular Diseases (Cardiovascular Disease)
11/2007 - 11/2004
2Fatty Liver
07/2006 - 10/2003
1Type 2 Diabetes Mellitus (MODY)
04/2008
1Body Weight Changes
11/2007
1Metabolic Diseases (Metabolic Disease)
11/2006
1Body Weight (Weight, Body)
09/2006
1Glucose Intolerance
07/2006
1Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
06/2006
1Hyperandrogenism
06/2006
1Hypertension (High Blood Pressure)
11/2004
1Weight Loss (Weight Reduction)
02/2004
1Open-Angle Glaucoma (Glaucoma, Open Angle)
12/2003
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2003
1Fetal Growth Retardation (Intrauterine Growth Retardation)
09/2002

Drug/Important Bio-Agent (IBA)

1111-beta-Hydroxysteroid Dehydrogenase Type 1IBA
04/2008 - 07/2003
7Hydrocortisone (Cortisol)FDA LinkGeneric
11/2007 - 09/2002
5GlucocorticoidsIBA
05/2008 - 01/2003
211-beta-Hydroxysteroid Dehydrogenases (11beta Hydroxysteroid Dehydrogenase)IBA
05/2007 - 04/2004
1Choline (Choline Chloride)IBA
07/2006
1CarbenoxoloneIBA
03/2005
1Potassium Iodide (Pima)FDA Link
11/2004
1CortisoneIBA
10/2003
1Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
07/2003
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
05/2002