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Rogier Versteeg Selected Research

Neuroblastoma

11/2015Cyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent Neuroblastoma.
8/2015Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations.
7/2015Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism.
6/2015The role of histone demethylase KDM4B in Myc signaling in neuroblastoma.
2/2015MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis.
1/2015Whole-genome sequencing identifies patient-specific DNA minimal residual disease markers in neuroblastoma.
2/2014Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma.
2/2014Discovery and visualization of miRNA-mRNA functional modules within integrated data using bicluster analysis.
2/2014Newly-derived neuroblastoma cell lines propagated in serum-free media recapitulate the genotype and phenotype of primary neuroblastoma tumours.
1/2014Robust selection of cancer survival signatures from high-throughput genomic data using two-fold subsampling.
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Rogier Versteeg Research Topics

Disease

47Neuroblastoma
11/2015 - 03/2002
37Neoplasms (Cancer)
11/2015 - 03/2002
9Medulloblastoma
07/2014 - 02/2006
3Ganglioneuroma
05/2009 - 04/2008
2Residual Neoplasm
01/2015 - 02/2012
2Breast Neoplasms (Breast Cancer)
06/2014 - 01/2014
2Astrocytoma (Pilocytic Astrocytoma)
08/2013 - 12/2006
2Brain Neoplasms (Brain Tumor)
08/2013 - 07/2012
2Anoxia (Hypoxia)
01/2013 - 01/2010
1Retinoblastoma (Glioblastoma, Retinal)
11/2015
1Wilms Tumor (Wilm's Tumor)
02/2015
1Disease Progression
01/2015
1Kidney Neoplasms (Kidney Cancer)
01/2015
1Osteosarcoma (Osteogenic Sarcoma)
12/2014
1Tics (Tic)
02/2014
1Chromosomal Instability (Chromosome Stability)
08/2013
1Genomic Instability
08/2013
1Rhabdoid Tumor (Rhabdoid Tumors)
12/2012
1Ganglioneuroblastoma
05/2009
1Colorectal Neoplasms (Colorectal Cancer)
04/2008
1Adenoma (Adenomas)
04/2008
1Prostatic Neoplasms (Prostate Cancer)
10/2007
1Endometrial Neoplasms (Endometrial Cancer)
12/2006
1Choriocarcinoma
12/2006
1Primitive Neuroectodermal Tumors (PNET)
04/2002

Drug/Important Bio-Agent (IBA)

18Messenger RNA (mRNA)IBA
06/2014 - 03/2002
7Transcription Factors (Transcription Factor)IBA
07/2013 - 02/2008
6MicroRNAs (MicroRNA)IBA
02/2015 - 12/2011
5Phosphotransferases (Kinase)IBA
11/2015 - 04/2008
5Small Interfering RNA (siRNA)IBA
06/2015 - 04/2005
4Histones (Histone)IBA
06/2015 - 03/2009
3DNA (Deoxyribonucleic Acid)IBA
01/2015 - 05/2011
3beta CateninIBA
04/2008 - 01/2008
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2003 - 04/2002
2Histone DemethylasesIBA
06/2015 - 03/2009
2RNA (Ribonucleic Acid)IBA
01/2015 - 08/2013
2Otx Transcription FactorsIBA
03/2013 - 07/2012
2Lysine (L-Lysine)FDA Link
03/2013 - 03/2009
2OxygenIBA
01/2013 - 01/2010
2Carbon MonoxideIBA
01/2012 - 03/2010
2Tretinoin (Retinoic Acid)FDA LinkGeneric
07/2010 - 04/2009
2Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA
05/2009 - 01/2004
2ChromatinIBA
03/2009 - 04/2008
2Cyclin D1IBA
04/2008 - 03/2003
2TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
11/2003 - 04/2002
1nucleophosminIBA
11/2015
1CyclinsIBA
11/2015
14- (2,6- dichlorobenzoylamino)- 1H- pyrazole- 3- carboxylic acid piperidin-4-ylamideIBA
11/2015
1Cyclin-Dependent Kinase 2IBA
11/2015
1AgarIBA
07/2015
1Complement System Proteins (Complement)IBA
05/2015
13-Iodobenzylguanidine (Iobenguane)IBA
02/2015
1polo-like kinase 1IBA
12/2014
1Estrogens (Estrogen)FDA Link
06/2014
1Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
02/2014
1Serum-Free Culture MediaIBA
02/2014
1Adenocarcinoma of lungIBA
01/2014
1Protein Kinases (Protein Kinase)IBA
08/2013
1Small Nucleolar RibonucleoproteinsIBA
08/2013
1Telomerase (Telomerase Reverse Transcriptase)IBA
08/2013
1Biological Markers (Surrogate Marker)IBA
04/2013
1PI103IBA
04/2013
1ABT 263IBA
11/2012
1Genetic Markers (Genetic Marker)IBA
02/2012
1Alprostadil (Muse)FDA LinkGeneric
01/2012
1Doxycycline (Vibramycin)FDA LinkGeneric
10/2010
1anaplastic lymphoma kinaseIBA
09/2010
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
06/2010
1Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
05/2010
1LigandsIBA
03/2010
1roscovitineIBA
08/2009
1Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA
05/2009
1RetinoidsIBA
04/2009
1Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA
03/2009
1(N- acetylneuraminyl)- galactosylglucosylceramide N-acetylgalactosaminyltransferaseIBA
11/2008
1A-Form DNA (A-DNA)IBA
04/2008
1NBPhox proteinIBA
02/2008
1Annexin A5IBA
11/2007
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
11/2007
1CeruleninIBA
11/2007
1Carrier Proteins (Binding Protein)IBA
10/2007
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
02/2006
1trkB ReceptorIBA
10/2005
1Congenital central hypoventilation syndromeIBA
12/2004
1Proteins (Proteins, Gene)IBA
01/2004
1Caspase 8 (Caspase-8)IBA
07/2003

Therapy/Procedure

9Heterologous Transplantation (Xenotransplantation)
11/2015 - 03/2009
4Drug Therapy (Chemotherapy)
08/2015 - 07/2014
1Aftercare (After-Treatment)
11/2015
1Combined Modality Therapy
11/2015
1Therapeutics
08/2009