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Danila Valmori Selected Research

Antigens

07/2008Lentivector immunization induces tumor antigen-specific B and T cell responses in vivo.
08/2007Assessment of CD4+ T cells specific for the tumor antigen SSX-1 in cancer-free individuals.
03/2007Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors.
02/2007Epitope clustering in regions undergoing efficient proteasomal processing defines immunodominant CTL regions of a tumor antigen.
05/2006Processing of tumor-associated antigen by the proteasomes of dendritic cells controls in vivo T-cell responses.
01/2006Expression of synovial sarcoma X (SSX) antigens in epithelial ovarian cancer and identification of SSX-4 epitopes recognized by CD4+ T cells.
10/2005Identification of B cell epitopes recognized by antibodies specific for the tumor antigen NY-ESO-1 in cancer patients with spontaneous immune responses.
05/2005Distinct structural TCR repertoires in naturally occurring versus vaccine-induced CD8+ T-cell responses to the tumor-specific antigen NY-ESO-1.
08/2004The frequent expression of cancer/testis antigens provides opportunities for immunotherapeutic targeting of sarcoma.
10/2003Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine.
10/2003SSX antigens as tumor vaccine targets in human sarcoma.
09/2003Tumor-reactive, SSX-2-specific CD8+ T cells are selectively expanded during immune responses to antigen-expressing tumors in melanoma patients.
05/2003Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen.
02/2003Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1.
11/2002Dissecting TCR-MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: crucial role of interaction kinetics on functional outcomes.
08/2002Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations.
07/2002Functional analysis of HLA-A*0201/Melan-A peptide multimer+ CD8+ T cells isolated from an HLA-A*0201- donor: exploring tumor antigen allorestricted recognition.
02/2002Functional avidity of tumor antigen-specific CTL recognition directly correlates with the stability of MHC/peptide multimer binding to TCR.

Articles by Research Topic

Disease

21Neoplasms (Cancer)
07/2008 - 02/2002
7Melanoma (Melanoma, Malignant)
03/2007 - 02/2002
2Sarcoma (Soft Tissue Sarcoma)
08/2004 - 10/2003
1Vaccinia
09/2006
1Fowlpox
09/2006
1Colorectal Neoplasms (Colorectal Cancer)
09/2006
1Ovarian Neoplasms (Ovarian Cancer)
01/2006
1Synovial Sarcoma (Synovioma)
01/2006
1Testicular Neoplasms (Testicular Cancer)
08/2004
1Dissociative Disorders (Fugue)
05/2003
1Malaria
03/2002

Drug/Important Bio-Agent (IBA)

18AntigensIBA
07/2008 - 02/2002
3PeptidesIBA
11/2004 - 10/2002
3Peptide LibraryIBA
11/2002 - 04/2002
2EpitopesIBA
01/2006 - 10/2003
2HLA-A*0201 antigenIBA
11/2004 - 07/2002
2LigandsIBA
08/2002 - 04/2002
1VaccinesIBA
09/2006
1PerforinIBA
09/2006
1AntibodiesIBA
10/2005
1B-Lymphocyte Epitopes (B-Cell Epitope)IBA
10/2005
1HLA-A2 Antigen (HLA A2 Antigen)IBA
03/2002
1Proteasome Endopeptidase Complex (Proteasome)IBA
02/2002