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Thomas Unger Selected Research

telmisartan (Micardis)

3/2015Systolic blood pressure variation and mean heart rate is associated with cognitive dysfunction in patients with high cardiovascular risk.
6/2014Impact of telmisartan on cardiovascular outcome in hypertensive patients at high risk: a Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease subanalysis.
6/2013An update on telmisartan/hydrochlorothiazide combinations for the management of hypertensive patients with additional cardiovascular risk factors.
8/2012Impact of sex on cardiovascular outcome in patients at high cardiovascular risk: analysis of the Telmisartan Randomized Assessment Study in ACE-Intolerant Subjects With Cardiovascular Disease (TRANSCEND) and the Ongoing Telmisartan Alone and in Combination With Ramipril Global End Point Trial (ONTARGET).
1/2011Prevention and intervention studies with telmisartan, ramipril and their combination in different rat stroke models.
4/2010Telmisartan and hydrochlorothiazide combination therapy for the treatment of hypertension.
1/2010PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice.
12/2008Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation.
5/2008Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan.
10/2007Pharmacoeconomics and quality of life analysis of telmisartan in hypertension treatment.
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Thomas Unger Research Topics

Disease

29Hypertension (High Blood Pressure)
02/2014 - 01/2002
14Stroke (Strokes)
06/2014 - 06/2004
13Cardiovascular Diseases (Cardiovascular Disease)
03/2015 - 01/2002
13Heart Failure
02/2014 - 01/2002
12Inflammation
05/2015 - 03/2002
11Myocardial Infarction
07/2013 - 10/2002
8Fibrosis (Cirrhosis)
05/2015 - 01/2003
6Brain Ischemia (Cerebral Ischemia)
06/2014 - 04/2005
5Diabetic Nephropathies (Diabetic Nephropathy)
05/2015 - 03/2003
5Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
06/2014 - 03/2008
5Obesity
06/2013 - 04/2007
4Insulin Resistance
12/2014 - 06/2007
4Leukemia
04/2014 - 01/2011
4Atherosclerosis
02/2014 - 05/2003
4Ischemia
01/2010 - 10/2002
4Body Weight (Weight, Body)
06/2008 - 06/2004
3Albuminuria
05/2015 - 12/2005
3Type 2 Diabetes Mellitus (MODY)
12/2014 - 05/2004
3Weight Gain
07/2013 - 12/2005
3Neoplasms (Cancer)
12/2012 - 12/2011
3Aneurysm (Aneurysms)
01/2010 - 09/2004
3Cardiomegaly (Heart Hypertrophy)
07/2004 - 01/2002
3Infarction
11/2003 - 10/2002
2Diabetes Mellitus
05/2015 - 06/2013
2Cardiomyopathies (Cardiomyopathy)
10/2012 - 05/2006
2Disease Progression
10/2010 - 01/2008
2Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
09/2010 - 12/2003
2Coronary Artery Disease (Coronary Atherosclerosis)
09/2010 - 07/2008
2Abdominal Aortic Aneurysm
01/2010 - 12/2008
2Glucose Intolerance
01/2010 - 06/2008
2Necrosis
12/2008 - 03/2005
2Brain Injuries (Brain Injury)
05/2008 - 04/2005
2Abdominal Obesity
04/2007 - 01/2007
2Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
05/2006 - 09/2004
1Diabetes Complications
05/2015
1Leiomyosarcoma
05/2015
1Demyelinating Diseases (Demyelinating Disease)
01/2015
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2015
1Multiple Sclerosis
01/2015
1Kidney Diseases (Kidney Disease)
06/2013

Drug/Important Bio-Agent (IBA)

15Angiotensin IIIBA
05/2015 - 01/2002
15telmisartan (Micardis)FDA Link
03/2015 - 05/2003
12AngiotensinsIBA
05/2015 - 07/2004
11Type 2 Angiotensin ReceptorIBA
05/2015 - 04/2005
10Type 1 Angiotensin ReceptorIBA
05/2015 - 05/2004
10Ramipril (Altace)FDA LinkGeneric
03/2015 - 03/2003
10Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
08/2010 - 01/2002
9ReninIBA
01/2013 - 01/2002
6Insulin (Novolin)FDA Link
12/2014 - 03/2003
6Glucose (Dextrose)FDA LinkGeneric
12/2014 - 01/2007
6CollagenIBA
07/2013 - 12/2003
5candesartanIBA
01/2010 - 11/2003
5Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
07/2008 - 01/2004
4Interleukin-6 (Interleukin 6)IBA
12/2011 - 03/2005
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2011 - 03/2005
4PPAR gammaIBA
01/2010 - 09/2005
4Angiotensin Receptor AntagonistsIBA
01/2010 - 01/2003
3Proteins (Proteins, Gene)IBA
05/2015 - 12/2008
3Losartan (Cozaar)FDA LinkGeneric
11/2014 - 02/2005
3Hydrochlorothiazide (Esidrix)FDA LinkGeneric
06/2013 - 04/2007
3Brain-Derived Neurotrophic Factor (BDNF)IBA
03/2013 - 03/2005
3Transcription Factors (Transcription Factor)IBA
01/2013 - 01/2011
3olmesartanIBA
02/2012 - 01/2004
3Endothelins (Endothelin)IBA
11/2011 - 11/2006
3Messenger RNA (mRNA)IBA
01/2011 - 10/2002
2Matrix Metalloproteinase 9 (Gelatinase B)IBA
03/2014 - 02/2012
2Antihypertensive Agents (Antihypertensives)IBA
01/2013 - 03/2006
2olmesartan medoxomil (Votum)FDA Link
02/2012 - 01/2004
2CytokinesIBA
12/2011 - 03/2007
2Neprilysin (Neutral Endopeptidase)IBA
03/2011 - 08/2010
2valsartan (Vals)FDA Link
09/2010 - 07/2008
2aliskirenFDA Link
02/2010 - 01/2010
2Kininogens (Kininogen)IBA
01/2010 - 09/2004
2Nerve Growth Factors (Neurotrophins)IBA
12/2008 - 03/2008
2Captopril (Capoten)FDA LinkGeneric
07/2008 - 12/2005
2ThiazolidinedionesIBA
05/2008 - 08/2007
2PPAR alphaIBA
05/2008 - 05/2006
2Nerve Growth Factor (NGF)IBA
09/2007 - 03/2005
2Nitric Oxide (Nitrogen Monoxide)FDA Link
06/2007 - 03/2002
2LDL CholesterolIBA
06/2007 - 05/2003
2Metoprolol (Lopressor)FDA LinkGeneric
04/2007 - 12/2003
2Transforming Growth Factor beta (TGF-beta)IBA
03/2007 - 01/2004
2irbesartanFDA LinkGeneric
03/2007 - 01/2007
2MibefradilIBA
06/2004 - 10/2002
2icatibantIBA
03/2003 - 01/2003
2EnzymesIBA
10/2002 - 01/2002
1Cystatin CIBA
05/2015
1InterferonsIBA
01/2015
1Immunoglobulin M (IgM)IBA
12/2014
1Blood Glucose (Blood Sugar)IBA
11/2014
1nephrinIBA
11/2014
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
06/2014
1Endothelin-1 (Endothelin 1)IBA
06/2014
1Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
03/2014
1Transforming Growth Factors (Transforming Growth Factor)IBA
03/2014
1AldosteroneIBA
02/2014
1Cannabinoid Receptors (Cannabinoid Receptor)IBA
07/2013
1rimonabantIBA
07/2013

Therapy/Procedure

3Ligation
12/2008 - 10/2002
2Denervation
05/2012 - 08/2010