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Takuji Toyama Selected Research

Nicorandil (SG 75)

4/2015Effects of adding intravenous nicorandil to standard therapy on cardiac sympathetic nerve activity and myocyte dysfunction in patients with acute decompensated heart failure.
1/2014Effects of oral nicorandil therapy on sympathetic nerve activity and cardiac events in patients with chronic heart failure: subanalysis of our previous report using propensity score matching.
10/2007Long-term nicorandil therapy improves cardiac sympathetic nerve activity after reperfusion therapy in patients with first acute myocardial infarction.
9/2005Comparative effects of nicorandil with isosorbide mononitrate on cardiac sympathetic nerve activity and left ventricular function in patients with ischemic cardiomyopathy.
3/2005Effects of nicorandil on cardiac sympathetic nerve activity after reperfusion therapy in patients with first anterior acute myocardial infarction.
10/2002Nicorandil infusion leads to good recovery from ischemia of left ventricular regional work in comparison with nitroglycerin.

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Takuji Toyama Research Topics

Disease

22Heart Failure
04/2015 - 10/2002
14Myocardial Infarction
05/2011 - 05/2003
11Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
02/2009 - 08/2002
5Death (Near-Death Experience)
01/2014 - 06/2008
4Myocardial Ischemia (Ischemic Heart Diseases)
04/2015 - 07/2005
4Ischemia
07/2014 - 10/2002
4Heart Diseases (Heart Disease)
01/2014 - 11/2002
3Fibrosis (Cirrhosis)
01/2012 - 04/2008
3Ventricular Remodeling
12/2007 - 02/2003
2Chest Pain (Chest Pains)
06/2014 - 07/2005
2Cicatrix (Scar)
01/2012 - 03/2009
2Central Sleep Apnea (Central Sleep Apnea Syndrome)
02/2009 - 01/2007
2Hypertrophy
06/2008 - 11/2002
2Atrial Fibrillation
04/2005 - 11/2004
1Diabetes Mellitus
10/2014
1AIDS-Related Complex (ARC)
10/2014
1Spasm (Spasms)
06/2014
1Tachycardia (Tachyarrhythmias)
06/2012
1Hypertension (High Blood Pressure)
01/2012
1Coronary Artery Disease (Coronary Atherosclerosis)
05/2011
1Apnea
02/2009
1Reperfusion Injury
06/2008
1Thrombosis (Thrombus)
01/2008
1Atherosclerotic Plaque (Atheroma)
06/2007
1Cardiomyopathies (Cardiomyopathy)
09/2005
1Sarcoidosis (Schaumann Disease)
12/2004
1Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
11/2002
1Angina Pectoris
10/2002
1Hyperplasia
05/2002

Drug/Important Bio-Agent (IBA)

6Nicorandil (SG 75)IBA
04/2015 - 10/2002
63-Iodobenzylguanidine (Iobenguane)IBA
01/2014 - 01/2007
5Adenosine Triphosphate (ATP)IBA
04/2015 - 09/2005
5Spironolactone (Aldactone)FDA LinkGeneric
07/2013 - 10/2002
4Potassium Channels (Potassium Channel)IBA
04/2015 - 09/2005
4Atrial Natriuretic Factor (ANF)IBA
09/2014 - 07/2004
4carvedilol (Coreg)FDA LinkGeneric
01/2008 - 10/2003
3Glucose (Dextrose)FDA LinkGeneric
10/2014 - 09/2004
3AngiotensinsIBA
12/2007 - 06/2003
3candesartanIBA
12/2007 - 11/2002
3DobutamineFDA LinkGeneric
11/2004 - 08/2002
2AldosteroneIBA
09/2014 - 08/2005
2omega-Chloroacetophenone (Mace)IBA
01/2014 - 01/2011
2Connective Tissue Growth FactorIBA
01/2012 - 04/2008
2OxygenIBA
02/2009 - 01/2007
2Amiodarone (Amiodarona)FDA LinkGeneric
01/2008 - 03/2004
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
08/2005 - 06/2003
2Creatine Kinase (Creatine Phosphokinase)IBA
03/2005 - 11/2003
2Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
12/2004 - 09/2004
2Metoprolol (Lopressor)FDA LinkGeneric
03/2004 - 10/2003
1CalciumIBA
10/2014
1Acetylcholine (Acetylcholine Chloride)FDA Link
06/2014
1Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
07/2013
1olmesartanIBA
01/2012
1Amlodipine (Norvasc)FDA LinkGeneric
01/2012
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
05/2011
1tyramine-deoxysorbitolIBA
05/2011
1Norepinephrine (Noradrenaline)FDA LinkGeneric
10/2007
1isosorbide-5-mononitrate (Ismo)FDA LinkGeneric
09/2005
1PerindoprilFDA LinkGeneric
08/2005
1EnalaprilFDA LinkGeneric
08/2005
1N 30IBA
04/2005
1pentadecanoic acidIBA
03/2005
1iodofiltic acidIBA
03/2005
1technetium Tc 99m 1,2- bis(bis(2- ethoxyethyl)phosphino)ethane (Myoview)FDA Link
11/2004
1Insulin (Novolin)FDA Link
09/2004
1ThalliumIBA
09/2004
1DiureticsIBA
07/2004
1Dopamine (Intropin)FDA LinkGeneric
07/2004
1Technetium (Technetium 99m)IBA
11/2003
1tranilast (N 5')IBA
10/2003
1Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2003
1valsartan (Vals)FDA Link
06/2003
1Brain Natriuretic Peptide (Natrecor)FDA Link
11/2002
1candesartan cilexetil (Amias)FDA Link
11/2002
1Nitroglycerin (Dynamite)FDA LinkGeneric
10/2002

Therapy/Procedure

4Stents
01/2008 - 05/2002
4Angioplasty (Angioplasty, Transluminal)
02/2007 - 10/2002
3Cardiac Resynchronization Therapy
03/2009 - 01/2004
2Cryosurgery
04/2005 - 11/2004
1Sympathectomy (Sympathectomies)
06/2012
1Gamma Cameras (Gamma Camera)
04/2009
1Denervation
06/2008
1Therapeutics
10/2007
1Coronary Atherectomy
06/2007
1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
07/2005
1Thrombectomy
11/2003
1Coronary Balloon Angioplasty (Percutaneous Transluminal Coronary Angioplasty)
05/2003
1Intravenous Infusions
10/2002
1Aftercare (After-Treatment)
08/2002