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Yoshiki Tokura Selected Research

Ketoprofen (Orudis)

8/2012Addition of UVA-absorber butyl methoxy dibenzoylmethane to topical ketoprofen formulation reduces ketoprofen-photoallergic reaction.
3/2009Skin application of ketoprofen systemically suppresses contact hypersensitivity by inducing CD4(+) CD25(+) regulatory T cells.
11/2008Photocontact dermatitis to ketoprofen presenting with erythema multiforme.
8/2007Stimulation of Langerhans cells with ketoprofen plus UVA in murine photocontact dermatitis to ketoprofen.
2/2006Establishment of murine model of allergic photocontact dermatitis to ketoprofen and characterization of pathogenic T cells.

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Yoshiki Tokura Research Topics

Disease

13Atopic Dermatitis (Atopic Eczema)
12/2015 - 11/2002
12Neoplasms (Cancer)
01/2015 - 08/2002
10Skin Diseases
04/2015 - 04/2002
10Hypersensitivity (Allergy)
12/2013 - 05/2002
10Contact Dermatitis (Eczema, Contact)
07/2013 - 04/2002
8Drug Eruptions (Drug Eruption)
07/2015 - 09/2006
7Psoriasis (Pustulosis Palmaris et Plantaris)
09/2014 - 11/2008
7Photoallergic Dermatitis (Photoallergy)
08/2012 - 08/2003
6Acne Vulgaris
08/2013 - 08/2003
5Mycosis Fungoides
01/2014 - 06/2005
4Inflammation
11/2014 - 01/2007
4Alopecia Areata
11/2014 - 02/2004
3Pemphigus (Pemphigus Vulgaris)
06/2015 - 04/2009
3Infection
11/2014 - 12/2003
3Dermatitis
07/2014 - 05/2012
3Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
03/2013 - 03/2005
3Neoplasm Metastasis (Metastasis)
01/2013 - 06/2010
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/2012 - 01/2011
3Alopecia (Baldness)
12/2011 - 08/2007
3Necrosis
07/2010 - 02/2007
2Bullous Pemphigoid (Pemphigoid)
04/2015 - 06/2011
2Hyperhidrosis
01/2015 - 08/2008
2Wounds and Injuries (Trauma)
11/2014 - 12/2012
2Urticaria (Hives)
01/2014 - 09/2012
2Palmoplantar Keratoderma (Keratosis Palmaris et Plantaris)
11/2013 - 05/2009
2Acute Generalized Exanthematous Pustulosis
05/2013 - 12/2010
2Primary Cutaneous Anaplastic Large Cell Lymphoma
01/2013 - 11/2007
2Ichthyosis (Xeroderma)
09/2012 - 04/2010
2Dermatomycoses (Dermatophytosis)
07/2012 - 01/2008
2Pruritus (Itching)
07/2012 - 02/2011
2B-Cell Lymphoma (Lymphoma, B Cell)
03/2012 - 11/2009
2Erythema
05/2011 - 03/2009
2Immune System Diseases (Immune Disorders)
12/2010 - 09/2007
2Eosinophilia
10/2010 - 11/2009
2Diabetes Mellitus
01/2010 - 11/2003
2Erythema Multiforme
11/2008 - 09/2006
2Eczema
02/2008 - 08/2007
1Cellulitis
07/2015
1Acantholysis
06/2015
1Leg Ulcer
05/2015
1Primary Hypertrophic Osteoarthropathy (Hypertrophic Osteoarthropathy, Primary)
05/2015
1Vasculitis (Vasculitides)
02/2015
1Actinic Keratosis
01/2015
1Thrombosis (Thrombus)
01/2015
1Warts (Wart)
01/2015

Drug/Important Bio-Agent (IBA)

11ChemokinesIBA
11/2014 - 04/2002
7AntigensIBA
01/2013 - 04/2002
6Immunoglobulin E (IgE)IBA
04/2015 - 11/2009
6CytokinesIBA
11/2014 - 08/2002
6Interleukin-17 (Interleukin 27)IBA
07/2014 - 11/2008
6Interferon-gamma (Interferon, gamma)IBA
01/2014 - 04/2002
5interleukin-22 (IL-22)IBA
07/2014 - 12/2010
5Ketoprofen (Orudis)FDA LinkGeneric
08/2012 - 02/2006
4Interleukin-4 (Interleukin 4)IBA
12/2015 - 08/2007
4Immunoglobulin G (IgG)IBA
06/2015 - 04/2002
4DNA (Deoxyribonucleic Acid)IBA
09/2014 - 09/2004
4Prednisolone (Predate)FDA LinkGeneric
03/2013 - 02/2006
3NickelIBA
07/2015 - 03/2012
3AutoantibodiesIBA
06/2015 - 04/2009
3Immunoglobulins (Immunoglobulin)IBA
06/2015 - 04/2009
3olopatadine (Patanol)FDA Link
04/2015 - 07/2003
3InterleukinsIBA
09/2014 - 07/2010
3PeptidesIBA
07/2014 - 12/2003
3nadifloxacinIBA
08/2013 - 05/2006
3Methotrexate (Mexate)FDA LinkGeneric
05/2012 - 12/2003
2DesmogleinsIBA
06/2015 - 04/2009
2AntibodiesIBA
06/2015 - 12/2010
2Dinoprostone (PGE2)FDA Link
05/2015 - 01/2007
2Immunoglobulin A (IgA)IBA
02/2015 - 11/2012
2InterferonsIBA
09/2014 - 01/2014
2Calcitriol (Calcijex)FDA LinkGeneric
09/2014 - 05/2013
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2014 - 10/2013
2filaggrinIBA
03/2014 - 05/2010
2CalciumIBA
10/2013 - 05/2013
2adapalene (Differin)FDA LinkGeneric
08/2013 - 12/2011
2Interleukin-8 (Interleukin 8)IBA
05/2013 - 12/2010
2Chemokine ReceptorsIBA
10/2012 - 03/2012
2Interleukin-10 (Interleukin 10)IBA
07/2012 - 08/2007
2Substance PIBA
07/2012 - 10/2005
2ProstaglandinsIBA
12/2010 - 09/2007
2fingolimod (FTY720)FDA Link
10/2010 - 12/2008
2Insulin (Novolin)FDA Link
09/2010 - 01/2010
2Cisplatin (Platino)FDA LinkGeneric
06/2010 - 03/2009
2MacrolidesIBA
07/2009 - 03/2007
2Picryl Chloride (Trinitrochlorobenzene)IBA
03/2009 - 12/2003
2sparfloxacin (AT 4140)FDA Link
02/2007 - 12/2005
1thymic stromal lymphopoietinIBA
12/2015
1Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric
07/2015
1Desmoglein 3IBA
06/2015
1Local AnestheticsIBA
01/2015
1AutoantigensIBA
11/2014
1HormonesIBA
11/2014
1ProteomeIBA
10/2014

Therapy/Procedure

3Radiotherapy
06/2010 - 04/2005
2Phototherapy (Light Therapy)
03/2013 - 02/2006
2Immunotherapy
04/2010 - 04/2005
2Aftercare (After-Treatment)
07/2009 - 10/2005
1Blood Component Removal (Apheresis)
04/2015
1Cryosurgery
01/2015
1Cryotherapy (Therapy, Cold)
01/2015