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Harukuni Tokuda Selected Research

Neoplasms (Cancer)

02/2008Cancer chemopreventive activity of terpenoid coumarins from Ferula species.
01/2008Anti-tumor-Promoting activity of tibolone and its metabolites.
08/2007Cucurbitane-type triterpenoids from the fruits of Momordica charantia and their cancer chemopreventive effects.
06/2007Cancer chemopreventive effects of cycloartane-type and related triterpenoids in in vitro and in vivo models.
06/2007Triterpene acids from Poria cocos and their anti-tumor-promoting effects.
02/2007Anti-inflammatory and anti-tumor-promoting effects of triterpene acids and sterols from the fungus Ganoderma lucidum.
01/2007Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus.
09/2006Cancer chemopreventive effects and cytotoxic activities of the triterpene acids from the resin of Boswellia carteri.
08/2006Cancer chemopreventive effect of orally administrated lupane-type triterpenoid on ultraviolet light B induced photocarcinogenesis of hairless mouse.
05/2006Acerogenin M, a cyclic diarylheptanoid, and other phenolic compounds from Acer nikoense and their anti-inflammatory and anti-tumor-promoting effects.
01/2006Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects.
01/2006Potential cancer chemopreventive activity of simple isoquinolines, 1-benzylisoquinolines, and protoberberines.
10/2005Anti-tumor-initiating effects of monascin, an azaphilonoid pigment from the extract of Monascus pilosus fermented rice (red-mold rice).
07/2005Cancer preventive agents, Part 2: Synthesis and evaluation of 2-phenyl-4-quinolone and 9-oxo-9,10-dihydroacridine derivatives as novel antitumor promoters.
03/2005Chemical constituents of Murraya siamensis: three coumarins and their anti-tumor promoting effect.
03/2005Cancer chemopreventive activity of lupane- and oleanane-type triterpenoids from the cones of Liquidamber styraciflua.
12/2004Potential anti-tumor promoting activity of lupane-type triterpenoids from the stem bark of Glochidion zeylanicum and Phyllanthus flexuosus.
10/2004Cancer chemopreventive activity of 3beta-methoxyserrat-14-en-21beta-ol and several serratane analogs on two-stage mouse skin carcinogenesis.
09/2004Multidrug-resistant cancer cell susceptibility to cytotoxic quassinoids, and cancer chemopreventive effects of quassinoids and canthin alkaloids.
03/2004Cancer chemopreventive effects of polyunsaturated fatty acids.
02/2004Cancer chemopreventive effect of phenothiazines and related tri-heterocyclic analogues in the 12-O-tetradecanoylphorbol-13-acetate promoted Epstein-Barr virus early antigen activation and the mouse skin two-stage carcinogenesis models.
01/2004Cancer prevention by antioxidants.
07/2003Cancer chemopreventive effects of oral feeding alpha-tocopherol on ultraviolet light B induced photocarcinogenesis of hairless mouse.
06/2003H-ras mutations at codon 61 or 13 in tumors initiated with a NO donor in mouse skin.
06/2003Cancer preventive potential of trichothecenes from Trichothecium roseum.
05/2003Isolation, structural elucidation, and inhibitory effects of terpenoid and lipid constituents from sunflower pollen on Epstein-Barr virus early antigen induced by tumor promoter, TPA.
04/2003Cancer chemopreventive activity of acridone alkaloids on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
03/2003Synthesis and anti-tumor-promoting activity of glycoglycerolipid analogues lacking the glycerol backbone.
03/2003Chemical constituents of Calophyllum brasiliense. 2. Structure of three new coumarins and cancer chemopreventive activity of 4-substituted coumarins.
02/2003Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot.
02/2003Polyprenylated benzophenones from Garcinia assigu and their potential cancer chemopreventive activities.
02/2003Chemical constituents of Garcinia fusca: structure elucidation of eight new xanthones and their cancer chemopreventive activity.
02/2003Anti-tumor promoting effect of glycosides from Prunus persica seeds.
11/2002Inhibitory effects of cucurbitane glycosides and other triterpenoids from the fruit of Momordica grosvenori on epstein-barr virus early antigen induced by tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
06/2002Cancer chemopreventive effects of a Brazilian folk medicine, Juca, on in vivo two-stage skin carcinogenesis.
04/2002Inhibition of tumor-promoting effects by poricoic acids G and H and other lanostane-type triterpenes and cytotoxic activity of poricoic acids A and G from Poria cocos.
03/2002Microbial transformations of two lupane-type triterpenes and anti-tumor-promoting effects of the transformation products.
03/2002Chemical constituents of Calophyllum brasiliensis: structure elucidation of seven new xanthones and their cancer chemopreventive activity.
02/2002Cancer chemopreventive activity of flavanones on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
02/2002Anti-inflammatory and anti-tumor-promoting effects of cucurbitane glycosides from the roots of Bryonia dioica.
02/2002Studies on cancer chemoprevention by traditional folk medicines XXIV. Inhibitory effect of a coumarin derivative, 7-isopentenyloxycoumarin, against tumor-promotion.

Articles by Research Topic

Disease

41Neoplasms (Cancer)
02/2008 - 02/2002
1Leukemia
09/2003

Drug/Important Bio-Agent (IBA)

4AcidsIBA
06/2007 - 04/2002
4lupaneIBA
08/2006 - 03/2002
3CoumarinsIBA
02/2008 - 03/2003
3cucurbitaneIBA
08/2007 - 02/2002
3Epstein-Barr virus early antigenIBA
02/2004 - 11/2002
3GlycosidesIBA
02/2003 - 02/2002
2AlkaloidsIBA
09/2004 - 04/2003
2XanthonesIBA
02/2003 - 03/2002
2TriterpenesIBA
04/2002 - 03/2002
1tiboloneIBA
01/2008
1cycloartaneIBA
06/2007
1SterolsIBA
02/2007
1inotodiolIBA
01/2007
1acerogenin MIBA
05/2006
1IsoquinolinesIBA
01/2006
1ChalconesIBA
01/2006
1monascinIBA
10/2005
12-phenyl-4-oxohydroquinolineIBA
07/2005
19-oxo-9,10-dihydroacridineIBA
07/2005
1oleananeIBA
03/2005
13beta-methoxyserrat-14-en-21beta-olIBA
10/2004
1QuassinsIBA
09/2004
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
03/2004
1PhenothiazinesIBA
02/2004
1AntioxidantsIBA
01/2004
1zoledronic acid (zoledronate)FDA Link
09/2003
1imatinib (Gleevec)FDA Link
09/2003
1alpha-TocopherolFDA Link
07/2003
1Codon (Codons)IBA
06/2003
1TrichothecenesIBA
06/2003
1acridoneIBA
04/2003
1Glycerol (Glycerine)FDA LinkGeneric
03/2003
1glycerolglycolipidsIBA
03/2003
1BenzophenonesIBA
02/2003
19,10-Dimethyl-1,2-benzanthracene (DMBA)IBA
02/2003
1Phenobarbital (Luminal)FDA Link
02/2003
1FlavanonesIBA
02/2002
17-isopentenyloxycoumarinIBA
02/2002
1coumarinIBA
02/2002

Therapy/Procedure

2Chemoprevention
02/2003 - 02/2002
1Traditional Medicine (Folk Remedies)
06/2002