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Norio Takagi Selected Research

Brain Ischemia (Cerebral Ischemia)

5/2013Injection of neural progenitor cells attenuates decrease in level of connexin 43 in brain capillaries after cerebral ischemia.
3/2013Intravenous injection of neural progenitor cells facilitates angiogenesis after cerebral ischemia.
11/2012Effects of metabotropic glutamate mGlu5 receptor antagonist on tyrosine phosphorylation of NMDA receptor subunits and cell death in the hippocampus after brain ischemia in rats.
4/2012Transient focal cerebral ischemia differentially decreases Homer1a and 1b/c contents in the postsynaptic density.
3/2011NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion.
1/2011Intravenous injection of neural progenitor cells improves cerebral ischemia-induced learning dysfunction.
10/2010Metabotropic glutamate mGlu5 receptor-mediated serine phosphorylation of NMDA receptor subunit NR1 in hippocampal CA1 region after transient global ischemia in rats.
9/2010mGluR1 antagonist decreased NADPH oxidase activity and superoxide production after transient focal cerebral ischemia.
8/2010Prostanoid EP1 receptor antagonist reduces blood-brain barrier leakage after cerebral ischemia.
10/2009[Pathology and strategies for the treatment of ischemic brain injury].
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Norio Takagi Research Topics

Disease

30Brain Ischemia (Cerebral Ischemia)
05/2013 - 01/2002
21Ischemia
01/2014 - 01/2003
16Embolism (Embolus)
05/2013 - 01/2002
5Brain Injuries (Brain Injury)
05/2013 - 02/2004
4Myocardial Infarction
05/2014 - 01/2013
4Neurodegenerative Diseases (Neurodegenerative Disease)
10/2009 - 12/2005
4Wounds and Injuries (Trauma)
11/2007 - 03/2006
3Acute Promyelocytic Leukemia
01/2016 - 03/2014
3Neoplasms (Cancer)
08/2014 - 01/2002
3Cerebral Infarction
08/2010 - 06/2008
2Leukemia
01/2016 - 12/2013
2Necrosis
01/2015 - 07/2003
2Heart Failure
05/2014 - 01/2013
2Shock
01/2013 - 01/2013
2Transient Ischemic Attack
03/2011 - 05/2004
2Hypertrophy
02/2008 - 01/2004
2Intracranial Embolism
11/2007 - 01/2006
2Stroke (Strokes)
02/2005 - 10/2002
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
10/2014
1Hematologic Neoplasms (Hematological Malignancy)
12/2013
1Hypertension (High Blood Pressure)
07/2010
1Cardiomyopathies (Cardiomyopathy)
12/2009
1Dementia (Dementias)
10/2009
1Brain Edema (Cerebral Edema)
12/2008
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
06/2008
1Fibrosis (Cirrhosis)
02/2008
1Multi-Infarct Dementia (Dementia, Multi Infarct)
02/2005

Drug/Important Bio-Agent (IBA)

10Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
10/2009 - 07/2004
8N-Methylaspartate (NMDA)IBA
11/2012 - 01/2003
7Tyrosine (L-Tyrosine)FDA Link
11/2012 - 01/2003
6Proteins (Proteins, Gene)IBA
05/2013 - 01/2006
4Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
10/2010 - 02/2002
4occludinIBA
08/2010 - 01/2006
4glucuronyl glucosamine glycan sulfate (Vessel)IBA
10/2009 - 05/2004
4Brain-Derived Neurotrophic Factor (BDNF)IBA
05/2008 - 05/2002
4Phosphotransferases (Kinase)IBA
03/2006 - 02/2002
4nefiracetamIBA
01/2005 - 10/2002
4Adenylate Cyclase (Adenylyl Cyclase)IBA
03/2003 - 01/2002
3Transcription Factors (Transcription Factor)IBA
01/2013 - 05/2004
3NADPH Oxidase (NAD(P)H oxidase)IBA
03/2011 - 10/2006
3Calmodulin (Calcium-Dependent Activator Protein)IBA
04/2003 - 01/2002
2arseniteIBA
01/2016 - 07/2015
2Small Heat-Shock ProteinsIBA
05/2014 - 01/2013
2HSP72 Heat-Shock ProteinsIBA
01/2013 - 01/2013
2Glutamic Acid (Glutamate)FDA Link
11/2012 - 10/2010
2Nerve Growth Factors (Neurotrophins)IBA
01/2011 - 03/2008
2metabotropic glutamate receptor type 1IBA
09/2010 - 06/2008
2Glutamate Receptors (Glutamate Receptor)IBA
10/2009 - 12/2005
2Dihydrotachysterol (AT 10)IBA
05/2008 - 01/2003
2tanshinone VIIBA
02/2008 - 01/2004
2Apoptosis Inducing FactorIBA
11/2007 - 11/2006
2Bromodeoxyuridine (BrdU)IBA
02/2005 - 05/2004
2acetamideIBA
01/2005 - 10/2002
2salicylhydroxamic acid (SHAM)IBA
05/2004 - 01/2003
2imidodiphosphonic acidIBA
05/2002 - 01/2002
2OF 900IBA
05/2002 - 01/2002
1ArsenicIBA
01/2016
1arsenic trioxide (Trisenox)FDA Link
01/2016
1delphinidinIBA
07/2015
1Neuroprotective AgentsIBA
01/2015
1prolinedithiocarbamate (PDTC)IBA
10/2014
1pyrrolidine dithiocarbamic acidIBA
10/2014
1Cisplatin (Platino)FDA LinkGeneric
10/2014
1p38 Mitogen-Activated Protein KinasesIBA
08/2014
1SB 203580IBA
08/2014
1Histones (Histone)IBA
08/2014
1Heat-Shock Proteins (Heat-Shock Protein)IBA
05/2014
1geranylgeranylacetone (teprenone)IBA
05/2014
1Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
03/2014
1Tretinoin (Retinoic Acid)FDA LinkGeneric
03/2014
1MicroRNAs (MicroRNA)IBA
01/2014
1Liposomes (Liposome)IBA
01/2014
1casticinIBA
12/2013
1Aquaporin 4IBA
05/2013
1Connexin 43 (Connexin43)IBA
05/2013
1Cadherins (E-Cadherin)IBA
05/2013
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2013
1src-Family KinasesIBA
11/2012
1Deoxycholic Acid (Sodium Deoxycholate)IBA
10/2010
1Serine (L-Serine)FDA Link
10/2010
1Superoxides (Superoxide)IBA
09/2010
1SC 51089IBA
08/2010
1Vasopressin Receptors (Arginine Vasopressin Receptor)IBA
07/2010
1Glycoproteins (Glycoprotein)IBA
12/2009
1DystrophinIBA
12/2009
1OxygenIBA
10/2009
1Glucose (Dextrose)FDA LinkGeneric
10/2009
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
06/2008
1alpha-methyl-4-carboxyphenylglycineIBA
06/2008
1Ionotropic Glutamate ReceptorsIBA
05/2007
1PolymersIBA
11/2006
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
11/2006
1Messenger RNA (mRNA)IBA
05/2005
1Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA
01/2005
1Cyclic AMP (AMP, Cyclic)IBA
01/2005
1Synapsins (Synapsin I)IBA
01/2005

Therapy/Procedure

22Microspheres (Microsphere)
05/2013 - 01/2002
3Ligation
05/2014 - 01/2013
3Intravenous Injections
05/2013 - 01/2011
1Transplantation (Transplant Recipients)
03/2013