HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Frank Speleman Selected Research

Neuroblastoma

11/2015Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma.
9/2015MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma.
8/2015Mutational dynamics between primary and relapse neuroblastomas.
3/2015miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin.
3/2015MYCN-targeting miRNAs are predominantly downregulated during MYCN‑driven neuroblastoma tumor formation.
1/2015Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma.
1/2015Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma.
9/2014Emergence of new ALK mutations at relapse of neuroblastoma.
5/2014Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma.
2/2014Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma.
For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password:


Frank Speleman Research Topics

Disease

48Neuroblastoma
11/2015 - 01/2003
44Neoplasms (Cancer)
08/2015 - 07/2003
10Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
08/2015 - 04/2010
8Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2015 - 11/2010
6Leukemia
08/2015 - 04/2010
3Medulloblastoma
05/2015 - 07/2012
3Neoplasm Metastasis (Metastasis)
01/2013 - 03/2010
2Chromosome Aberrations (Chromosome Abnormalities)
07/2012 - 10/2009
2Hodgkin Disease (Hodgkin's Disease)
12/2009 - 07/2007
1Pathologic Processes
05/2015
1Colonic Neoplasms (Colon Cancer)
09/2013
1Retinoblastoma (Glioblastoma, Retinal)
09/2012
1T-Cell Leukemia (Leukemia, T Cell)
11/2010
1Breast Neoplasms (Breast Cancer)
03/2010
1Lymphoma (Lymphomas)
12/2009
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
10/2009
1Glioma (Gliomas)
01/2008
1Anoxia (Hypoxia)
08/2006
1Trisomy (Trisomies)
07/2005
1Melorheostosis
11/2004
1Osteopoikilosis
11/2004
1Paraganglioma (Paragangliomas)
08/2004
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2004
1B-Cell Lymphoma (Lymphoma, B Cell)
10/2003
1Merkel Cell Carcinoma
09/2002

Drug/Important Bio-Agent (IBA)

21MicroRNAs (MicroRNA)IBA
09/2015 - 12/2008
14Messenger RNA (mRNA)IBA
08/2015 - 08/2006
11DNA (Deoxyribonucleic Acid)IBA
10/2015 - 02/2004
8Transcription Factors (Transcription Factor)IBA
03/2015 - 09/2002
7Phosphotransferases (Kinase)IBA
01/2015 - 03/2006
6anaplastic lymphoma kinaseIBA
05/2014 - 10/2003
5Histones (Histone)IBA
11/2015 - 09/2013
5RNA (Ribonucleic Acid)IBA
12/2014 - 01/2009
5nutlin 3IBA
01/2013 - 10/2006
4Small Interfering RNA (siRNA)IBA
03/2015 - 07/2012
3ChromatinIBA
11/2015 - 08/2014
3tyrosine receptor (receptor, tyrosine)IBA
09/2014 - 07/2010
3First StepIBA
06/2009 - 02/2004
2Complementary DNA (cDNA)IBA
03/2015 - 02/2004
2Proteins (Proteins, Gene)IBA
08/2014 - 01/2008
2Carbon MonoxideIBA
09/2012 - 01/2012
2Biological Markers (Surrogate Marker)IBA
01/2012 - 11/2010
2Cadherins (E-Cadherin)IBA
01/2012 - 03/2010
1CyclinsIBA
01/2015
16- acetyl- 8- cyclopentyl- 5- methyl- 2- (5- piperazin- 1- ylpyridin- 2- ylamino)- 8H- pyrido(2,3- d)pyrimidin- 7- oneIBA
01/2015
1Cyclin D1IBA
01/2015
1Untranslated RNA (Noncoding RNA)IBA
12/2014
1N- (4- bromo- 2- fluorophenyl)- 6- methoxy- 7- ((1- methylpiperidin- 4- yl)methoxy)quinazolin- 4- amine (ZD6474)IBA
05/2014
1Kabuki syndromeIBA
05/2014
1Lysine (L-Lysine)FDA Link
09/2013
1GTP-Binding Proteins (G-Protein)IBA
01/2013
1Retinaldehyde (Retinal)IBA
09/2012
1Oncogene Proteins (Oncogene Protein)IBA
07/2012
1N-Ac-CHAVC-NH2IBA
01/2012
1A-Form DNA (A-DNA)IBA
01/2012
1Genetic Markers (Genetic Marker)IBA
10/2011
1Caspase 8 (Caspase-8)IBA
08/2011
1Tumor Suppressor Protein p14ARF (p14ARF)IBA
06/2011
1CI1033 (CI 1033)IBA
07/2010
1erlotinib (CP 358,774)FDA Link
07/2010
1tranilast (N 5')IBA
11/2009
1Interleukin-2 (IL2)IBA
10/2009
1CPG-oligonucleotideIBA
10/2009
1Polyribonucleotide Nucleotidyltransferase (Polynucleotide Phosphorylase)IBA
06/2009
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2008
1Indicators and Reagents (Reagents)IBA
09/2008
15' Untranslated Regions (5' UTR)IBA
03/2008
1Protein Tyrosine PhosphatasesIBA
03/2008
1decitabine (5-aza-2'-deoxycytidine)FDA Link
01/2008
1Protein Isoforms (Isoforms)IBA
01/2008
1OxygenIBA
08/2006
1Neurofibromin 1 (Neurofibromin)IBA
03/2006
1Pyridinolcarbamate (P23)IBA
07/2005
1Buschke-Ollendorff syndromeIBA
11/2004
1Nonsense Codon (Nonsense Mutation)IBA
08/2004
1PlasticsIBA
01/2004
1ProteomeIBA
07/2003

Therapy/Procedure

6Heterologous Transplantation (Xenotransplantation)
03/2015 - 11/2009
5Drug Therapy (Chemotherapy)
11/2015 - 01/2013
2Hematopoietic Stem Cell Transplantation
08/2015 - 01/2015
2Lasers (Laser)
03/2012 - 07/2003
2Ligation
02/2011 - 01/2010
1Salvage Therapy
08/2015
1Oral Administration
11/2009