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Robert H Silverman Selected Research

Ribonucleases (Ribonuclease)

4/2014Ribonuclease L and metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs.
9/2013Role of ribonuclease L in viral pathogen-associated molecular pattern/influenza virus and cigarette smoke-induced inflammation and remodeling.
8/2013Ribonuclease L is not critical for innate restriction and adaptive immunity against Friend retrovirus infection.
5/2013RNase-L deficiency exacerbates experimental colitis and colitis-associated cancer.
12/2007Hepatitis C virus RNA: dinucleotide frequencies and cleavage by RNase L.
10/2003Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates.

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Robert H Silverman Research Topics

Disease

50Infection
04/2015 - 01/2002
18Neoplasms (Cancer)
04/2014 - 01/2002
15Prostatic Neoplasms (Prostate Cancer)
01/2012 - 02/2003
5Vesicular Stomatitis
09/2013 - 05/2003
4Melanoma (Melanoma, Malignant)
10/2014 - 01/2003
2Inflammation
10/2014 - 09/2013
2Ovarian Neoplasms (Ovarian Cancer)
04/2014 - 01/2002
2Demyelinating Diseases (Demyelinating Disease)
01/2011 - 10/2009
2Contagious Ecthyma (Orf)
12/2007 - 06/2007
2Herpes Genitalis (Genital Herpes)
08/2006 - 07/2005
2Carcinoma (Carcinomatosis)
01/2004 - 01/2002
1Genomic Instability
04/2014
1Chronic Obstructive Pulmonary Disease (COPD)
09/2013
1Viremia
08/2013
1Retroviridae Infections (Infection, Retrovirus)
08/2013
1Colitis
05/2013
1Hepatitis
06/2012
1Paramyxoviridae Infections (Parainfluenza)
02/2011
1Leukemia
01/2011
1Bacterial Infections (Bacterial Infection)
01/2011
1Encephalomyelitis (Myeloencephalitis)
10/2009
1T-Cell Leukemia (Leukemia, T Cell)
10/2008
1Multiple Sclerosis
12/2007
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell)
10/2005
1Herpetic Keratitis
07/2005
1Reoviridae Infections
02/2005

Drug/Important Bio-Agent (IBA)

43pppA(2'p5'A)n-dependent ribonuclease (RNase L)IBA
04/2015 - 01/2002
16RNA (Ribonucleic Acid)IBA
04/2015 - 02/2003
16InterferonsIBA
03/2015 - 01/2002
8LigasesIBA
06/2014 - 01/2003
6Ribonucleases (Ribonuclease)IBA
04/2014 - 10/2003
52',5'-oligoadenylate (PAPAPA)IBA
06/2014 - 01/2003
5eIF-2 Kinase (eIF 2 Kinase)IBA
09/2013 - 02/2005
52',5'-Oligoadenylate Synthetase (2',5' Oligoadenylate Synthetase)IBA
06/2012 - 02/2005
5DNA (Deoxyribonucleic Acid)IBA
01/2012 - 01/2003
5Messenger RNA (mRNA)IBA
02/2011 - 01/2003
4Proteins (Proteins, Gene)IBA
12/2011 - 05/2003
4Double-Stranded RNA (RNA, Double Stranded)IBA
09/2008 - 01/2003
4Interferon-betaIBA
01/2006 - 05/2002
3Adenosine Triphosphate (ATP)IBA
10/2014 - 06/2007
3Small Interfering RNA (siRNA)IBA
04/2014 - 09/2004
3Interferon Type IIBA
01/2014 - 01/2009
2Poly I-CIBA
10/2014 - 01/2014
2CytokinesIBA
10/2014 - 01/2014
2sunitinib (Sutent)FDA Link
09/2013 - 07/2011
2RNA Helicases (RNA Helicase)IBA
02/2011 - 08/2007
2Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2011 - 01/2009
2familial Prostate cancerIBA
01/2011 - 06/2007
2Androgen Receptors (Androgen Receptor)IBA
11/2010 - 01/2007
2Antiviral Agents (Antivirals)IBA
02/2008 - 12/2007
2Carrier Proteins (Binding Protein)IBA
01/2006 - 09/2005
2Complementary DNA (cDNA)IBA
10/2005 - 01/2002
1marenostrin (pyrin)IBA
10/2014
1Interleukin-18 (Interleukin 18)IBA
10/2014
1NigericinIBA
10/2014
1Particulate MatterIBA
10/2014
1Retroelements (Retrotransposon)IBA
04/2014
1Peptide Initiation Factors (Initiation Factor)IBA
09/2013
1SmokeIBA
09/2013
1Immunoglobulin G (IgG)IBA
08/2013
1AzoxymethaneIBA
05/2013
1Bacterial RNAIBA
05/2013
1Dextran SulfateIBA
05/2013
1Neutralizing AntibodiesIBA
01/2012
1Protein Isoforms (Isoforms)IBA
12/2011
1EnzymesIBA
11/2011
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
07/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2011
1phytoalexinsIBA
11/2010
1resveratrolIBA
11/2010
1HormonesIBA
11/2010
1tensins (tensin)IBA
11/2010
1PTEN Phosphohydrolase (PTEN Phosphatase)IBA
11/2010
1Integrase InhibitorsIBA
02/2010
1Dihydrotestosterone (Androstanolone)IBA
02/2010
1AndrogensIBA
02/2010
1AntibodiesIBA
01/2010
1Capsid Proteins (Capsid Protein)IBA
01/2010
1xenotropic and polytropic retrovirus receptorIBA
07/2009
1prostatic acid phosphataseIBA
07/2009
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2009
1MicroRNAs (MicroRNA)IBA
10/2008
1Deoxyribonucleases (DNase)IBA
10/2008
1Interleukin-10 (Interleukin 10)IBA
09/2008
1VaccinesIBA
02/2008
1Carbon MonoxideIBA
01/2008
1Complement System Proteins (Complement)IBA
01/2008
1Immunologic Factors (Immunomodulators)IBA
12/2007
1Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
08/2007
1Transcription Factors (Transcription Factor)IBA
01/2007
1transcription factor NF-AT c3IBA
01/2007
1LigandsIBA
01/2007
1Viral RNAIBA
03/2006
1Phosphatidylethanolamine Binding ProteinIBA
01/2006
1Growth Differentiation Factor 15IBA
10/2005
1Transforming Growth Factor beta (TGF-beta)IBA
10/2005
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2004
1Topoisomerase I InhibitorsIBA
12/2004

Therapy/Procedure

2Heterologous Transplantation (Xenotransplantation)
01/2012 - 01/2012
1Oncolytic Virotherapy
09/2013