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J Sieper Selected Research

infliximab (Remicade)

03/2008Multicenter open-label study with infliximab in active ankylosing spondylitis over 28 weeks in daily practice.
03/2008Persistent clinical efficacy and safety of anti-tumour necrosis factor alpha therapy with infliximab in patients with ankylosing spondylitis over 5 years: evidence for different types of response.
09/2007Radiographic progression in patients with ankylosing spondylitis after 4 yrs of treatment with the anti-TNF-alpha antibody infliximab.
02/2006Markov model into the cost-utility over five years of etanercept and infliximab compared with usual care in patients with active ankylosing spondylitis.
12/2005Persistent reduction of spinal inflammation as assessed by magnetic resonance imaging in patients with ankylosing spondylitis after 2 yrs of treatment with the anti-tumour necrosis factor agent infliximab.
10/2005Radiographic progression in patients with ankylosing spondylitis after 2 years of treatment with the tumour necrosis factor alpha antibody infliximab.
08/2005Decreased incidence of anterior uveitis in patients with ankylosing spondylitis treated with the anti-tumor necrosis factor agents infliximab and etanercept.
08/2005Infliximab for the treatment of ankylosing spondylitis.
05/2005Persistent clinical response to the anti-TNF-alpha antibody infliximab in patients with ankylosing spondylitis over 3 years.
02/2005Two year maintenance of efficacy and safety of infliximab in the treatment of ankylosing spondylitis.
10/2004[Measurement of quality of life in patients with active ankylosing spondylitis being treated with infliximab-a comparison of SF-36 and SF-12]
08/2003Long-term efficacy and safety of infliximab in the treatment of ankylosing spondylitis: an open, observational, extension study of a three-month, randomized, placebo-controlled trial.
04/2003Magnetic resonance imaging examinations of the spine in patients with ankylosing spondylitis, before and after successful therapy with infliximab: evaluation of a new scoring system.
11/2002Infliximab in the treatment of active and severe ankylosing spondylitis.
04/2002Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial.
12/2001Infliximab treatment of severe ankylosing spondylitis: one-year followup.
06/2000Successful treatment of active ankylosing spondylitis with the anti-tumor necrosis factor alpha monoclonal antibody infliximab.

Articles by Research Topic

Disease

41Ankylosing Spondylitis
03/2008 - 06/2000
7Necrosis
03/2008 - 04/2000
4Rheumatoid Arthritis
07/2003 - 04/2000
3Reactive Arthritis (Reiter Disease)
06/2002 - 02/2000
2Osteoarthritis
06/2002 - 11/2000
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
05/2007
1Back Pain (Backache)
09/2006
1Inflammation
12/2005
1Anterior Uveitis
08/2005
1Connective Tissue Diseases (Connective Tissue Disease)
01/2002
1Mixed Connective Tissue Disease (MCTD)
01/2002
1Syndrome
01/2002

Drug/Important Bio-Agent (IBA)

17infliximab (Remicade)FDA Link
03/2008 - 06/2000
9TNFR-Fc fusion protein (etanercept)FDA Link
12/2006 - 06/2003
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2007 - 06/2000
3Methotrexate (Mexate)FDA LinkGeneric
03/2007 - 04/2000
3AntigensIBA
06/2002 - 12/2000
2Sulfasalazine (Azulfidine)FDA LinkGeneric
09/2006 - 04/2002
2Aggrecans (Aggrecan)IBA
05/2005 - 07/2003
1celecoxib (Celebrex)FDA Link
03/2008
1Diclofenac (SR 38)FDA LinkGeneric
03/2008
1Transforming Growth Factor beta (TGF-beta)IBA
06/2006
1Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
02/2005
1leflunomide (Arava)FDA LinkGeneric
01/2005
1pamidronate (APD)FDA LinkGeneric
08/2003
1Interferon-gamma (Interferon, gamma)IBA
06/2003
1HLA-DRB1 antigen (HLA DRB1)IBA
06/2002
1Prednisolone (Predate)FDA LinkGeneric
01/2002
1Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2002
1Carbon MonoxideIBA
01/2002
1RadiumIBA
04/2001
1HLA-B27 Antigen (HLA B27 Antigen)IBA
01/2001
1Interleukin-1 (Interleukin 1)IBA
11/2000
1Interleukin-1beta (Interleukin 1 beta)IBA
11/2000
1AntibodiesIBA
11/2000
1Interleukin-10 (Interleukin 10)IBA
04/2000
1Interleukin-4 (Interleukin 4)IBA
04/2000
1Chaperonin 60IBA
02/2000