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J Sieper Selected Research

TNFR-Fc fusion protein (etanercept)

12/2006Etanercept 50 mg once weekly is as effective as 25 mg twice weekly in patients with ankylosing spondylitis.
02/2006Markov model into the cost-utility over five years of etanercept and infliximab compared with usual care in patients with active ankylosing spondylitis.
12/2005Outcome of patients with active ankylosing spondylitis after two years of therapy with etanercept: clinical and magnetic resonance imaging data.
09/2005Magnetic resonance imaging of the spine and the sacroiliac joints in ankylosing spondylitis and undifferentiated spondyloarthritis during treatment with etanercept.
08/2005Decreased incidence of anterior uveitis in patients with ankylosing spondylitis treated with the anti-tumor necrosis factor agents infliximab and etanercept.
03/2005Long-term efficacy and safety of etanercept after readministration in patients with active ankylosing spondylitis.
12/2004Outcomes of a multicentre randomised clinical trial of etanercept to treat ankylosing spondylitis.
06/2003Up regulation of the production of tumour necrosis factor alpha and interferon gamma by T cells in ankylosing spondylitis during treatment with etanercept.
06/2003Six-month results of a double-blind, placebo-controlled trial of etanercept treatment in patients with active ankylosing spondylitis.

Articles by Research Topic

Disease

41Ankylosing Spondylitis
03/2008 - 06/2000
7Necrosis
03/2008 - 04/2000
4Rheumatoid Arthritis
07/2003 - 04/2000
3Reactive Arthritis (Reiter Disease)
06/2002 - 02/2000
2Osteoarthritis
06/2002 - 11/2000
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
05/2007
1Back Pain (Backache)
09/2006
1Inflammation
12/2005
1Anterior Uveitis
08/2005
1Connective Tissue Diseases (Connective Tissue Disease)
01/2002
1Mixed Connective Tissue Disease (MCTD)
01/2002
1Syndrome
01/2002

Drug/Important Bio-Agent (IBA)

17infliximab (Remicade)FDA Link
03/2008 - 06/2000
9TNFR-Fc fusion protein (etanercept)FDA Link
12/2006 - 06/2003
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2007 - 06/2000
3Methotrexate (Mexate)FDA LinkGeneric
03/2007 - 04/2000
3AntigensIBA
06/2002 - 12/2000
2Sulfasalazine (Azulfidine)FDA LinkGeneric
09/2006 - 04/2002
2Aggrecans (Aggrecan)IBA
05/2005 - 07/2003
1celecoxib (Celebrex)FDA Link
03/2008
1Diclofenac (SR 38)FDA LinkGeneric
03/2008
1Transforming Growth Factor beta (TGF-beta)IBA
06/2006
1Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
02/2005
1leflunomide (Arava)FDA LinkGeneric
01/2005
1pamidronate (APD)FDA LinkGeneric
08/2003
1Interferon-gamma (Interferon, gamma)IBA
06/2003
1HLA-DRB1 antigen (HLA DRB1)IBA
06/2002
1Prednisolone (Predate)FDA LinkGeneric
01/2002
1Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2002
1Carbon MonoxideIBA
01/2002
1RadiumIBA
04/2001
1HLA-B27 Antigen (HLA B27 Antigen)IBA
01/2001
1Interleukin-1 (Interleukin 1)IBA
11/2000
1Interleukin-1beta (Interleukin 1 beta)IBA
11/2000
1AntibodiesIBA
11/2000
1Interleukin-10 (Interleukin 10)IBA
04/2000
1Interleukin-4 (Interleukin 4)IBA
04/2000
1Chaperonin 60IBA
02/2000