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Koichi Shudo Selected Research

Retinoids

10/2012Retinoids ameliorate insulin resistance in a leptin-dependent manner in mice.
5/2012Natural and synthetic retinoids afford therapeutic effects on intracerebral hemorrhage in mice.
1/2011A retinoic acid receptor agonist Am80 rescues neurons, attenuates inflammatory reactions, and improves behavioral recovery after intracerebral hemorrhage in mice.
6/2006[Retinoid therapy for autoimmune diseases].
11/2004A synthetic retinoid Am80 (tamibarotene) rescues the memory deficit caused by scopolamine in a passive avoidance paradigm.
3/2004Modifying effects of 1'-acetoxychavicol acetate (ACA) and the novel synthetic retinoids Re-80, Am-580 and Am-55P in a two-stage carcinogenesis model in female rats.
1/2003Effect of synthetic retinoid, TAC-101, on experimental autoimmune disease.
1/2003Clinically potential subclasses of retinoid synergists revealed by gene expression profiling.

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Koichi Shudo Research Topics

Disease

6Acute Promyelocytic Leukemia
03/2013 - 07/2009
4Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
08/2015 - 01/2003
4Alzheimer Disease (Alzheimer's Disease)
01/2014 - 07/2009
4Neoplasms (Cancer)
02/2013 - 01/2003
3Cerebral Hemorrhage
08/2014 - 01/2011
3Neuralgia (Stump Neuralgia)
07/2014 - 12/2012
3Memory Disorders (Memory Loss)
01/2014 - 11/2004
2Dizziness (Lightheadedness)
07/2014 - 01/2014
2Pain (Aches)
01/2014 - 12/2012
2Leukemia
01/2014 - 01/2003
2Insulin Resistance
01/2013 - 10/2012
2Hematoma
05/2012 - 01/2011
2Neurodegenerative Diseases (Neurodegenerative Disease)
07/2009 - 02/2009
2Atherosclerosis
07/2007 - 05/2006
2Autoimmune Diseases (Autoimmune Disease)
06/2006 - 01/2003
1Neuroblastoma
10/2015
1Optic Neuritis (Retrobulbar Neuritis)
08/2015
1Pulmonary Emphysema
12/2014
1Chronic Obstructive Pulmonary Disease (COPD)
12/2014
1Infection
11/2013
1Dementia (Dementias)
09/2013
1Neutropenia
02/2013
1Vasculitis (Vasculitides)
02/2013
1Iron Overload
01/2013
1Fatty Liver
10/2012
1Hemorrhage
01/2011
1Edema
01/2011
1Multiple Sclerosis
06/2009
1Spinal Cord Injuries (Spinal Cord Injury)
02/2009
1Hyperplasia
11/2006
1Psoriasis (Pustulosis Palmaris et Plantaris)
06/2006
1Body Weight (Weight, Body)
05/2006
1Vascular System Injuries
11/2005
1Neointima
11/2005
1Dyskinesias (Dyskinesia)
10/2004
1Movement Disorders (Movement Disorder)
10/2004
1Schizophrenia (Dementia Praecox)
10/2004
1Wilms Tumor (Wilm's Tumor)
03/2004
1Hypersensitivity (Allergy)
01/2003
1Experimental Arthritis
01/2003

Drug/Important Bio-Agent (IBA)

24Am 80 (tamibarotene)IBA
08/2015 - 01/2003
10Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
10/2015 - 07/2007
8RetinoidsIBA
10/2012 - 01/2003
7Tretinoin (Retinoic Acid)FDA LinkGeneric
08/2015 - 10/2002
4HX 630IBA
01/2014 - 01/2003
3gamma-Aminobutyric Acid (GABA)IBA
07/2014 - 12/2012
3pregabalin (Lyrica)FDA Link
07/2014 - 12/2012
3LigandsIBA
01/2014 - 10/2004
2Amyloid (Amyloid Fibrils)IBA
01/2014 - 07/2009
2Retinoid X Receptors (Retinoid X Receptor)IBA
01/2014 - 10/2004
2glucuronyl glucosamine glycan sulfate (Vessel)IBA
02/2013 - 11/2005
2AcidsIBA
12/2012 - 10/2002
2Collagenases (Collagenase)FDA Link
05/2012 - 01/2011
2Scopolamine (Hyoscine)FDA Link
01/2012 - 11/2004
2Benzoic Acid (Ucephan)FDA Link
02/2009 - 01/2003
2TAC 101IBA
11/2004 - 01/2003
1Mitogen-Activated Protein KinasesIBA
10/2015
1Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA
10/2015
1Pancreatic Elastase (Elastase)IBA
12/2014
1SiliconIBA
07/2014
1Carbon MonoxideIBA
01/2014
1linezolid (Zyvox)FDA Link
11/2013
1Vitamin A (Retinol)FDA LinkGeneric
09/2013
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
02/2013
1Recombinant Granulocyte Colony Stimulating Factor (Recombinant G CSF)IBA
02/2013
1IronIBA
01/2013
1Anticonvulsants (Antiepileptic Drugs)IBA
12/2012
1gabapentin (Neurontin)FDA LinkGeneric
12/2012
1Aminobutyric Acids (Aminobutyric Acid)IBA
12/2012
1Insulin (Novolin)FDA Link
10/2012
1LeptinIBA
10/2012
1Non-alcoholic Fatty Liver DiseaseIBA
10/2012
1CytokinesIBA
01/2012
1Heme Oxygenase-1IBA
01/2011
13-nitrotyrosineIBA
01/2011
1IT-M-07000IBA
12/2009
1cryptoxanthin (beta-cryptoxanthin)IBA
07/2007
1Apolipoproteins E (ApoE)IBA
05/2006
1ApolipoproteinsIBA
05/2006
1Lipoproteins (Lipoprotein)IBA
05/2006
1Interleukin-10 (Interleukin 10)IBA
05/2006
1Interleukin-6 (Interleukin 6)IBA
05/2006
1Scavenger Receptors (Scavenger Receptor)IBA
05/2006
1Small Interfering RNA (siRNA)IBA
11/2005
1retinoic acid receptor alphaIBA
11/2005
1Transcription Factors (Transcription Factor)IBA
11/2005
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
10/2004
1Antipsychotic Agents (Antipsychotics)IBA
10/2004
1Haloperidol (Haldol)FDA LinkGeneric
10/2004
1Dichlorodiphenyldichloroethane (DDD)IBA
03/2004
1Am 580 (Am580)IBA
03/2004
1Collagen Type II (Type II Collagen)IBA
01/2003
1Immunoglobulin G (IgG)IBA
01/2003

Therapy/Procedure

4Oral Administration
05/2012 - 11/2005
3Drug Therapy (Chemotherapy)
12/2014 - 10/2004
1Cutaneous Administration
01/2014
1Intraperitoneal Injections
02/2013
1Therapeutics
07/2009
1Drug-Eluting Stents
11/2005
1Stents
11/2005