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Kuslima Shogen Selected Research

Ribonucleases (Ribonuclease)

8/2009Local controlled delivery of anti-neoplastic RNAse to the brain.
4/2009Effect of Onconase on double-stranded RNA in vitro.
10/2008The cytotoxic ribonuclease onconase targets RNA interference (siRNA).
7/2008Mechanisms of enhanced tumoricidal efficacy of multiple small dosages of ranpirnase, the novel cytotoxic ribonuclease, on lung cancer.
7/2008Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines.
12/2007Cytostatic and cytotoxic properties of Amphinase: a novel cytotoxic ribonuclease from Rana pipiens oocytes.
9/2007The therapeutic mechanisms of ranpirnase-induced enhancement of radiation response on A549 human lung cancer.
4/2007Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase.
1/2007Possible mechanisms of improved radiation response by cytotoxic RNase, Onconase, on A549 human lung cancer xenografts of nude mice.
1/2007Antitumor efficacy of the cytotoxic RNase, ranpirnase, on A549 human lung cancer xenografts of nude mice.
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Kuslima Shogen Research Topics

Disease

11Neoplasms (Cancer)
11/2011 - 01/2003
7Mesothelioma
01/2010 - 01/2002
4Lung Neoplasms (Lung Cancer)
07/2008 - 01/2007
1Glioma (Gliomas)
08/2009
1Neuroblastoma
05/2007
1Fever (Fevers)
04/2007
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2007
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
12/2004
1Carcinoma (Carcinomatosis)
01/2003

Drug/Important Bio-Agent (IBA)

15ranpirnase (Pannon)IBA
11/2011 - 01/2002
11Ribonucleases (Ribonuclease)IBA
08/2009 - 12/2004
2RNA (Ribonucleic Acid)IBA
01/2010 - 01/2007
1Pancreatic Ribonuclease (Ribonuclease A)IBA
11/2011
1Interleukin-6 (Interleukin 6)IBA
01/2010
1Proteins (Proteins, Gene)IBA
08/2009
1sebacic acidIBA
08/2009
1Carbon MonoxideIBA
08/2009
1Poly(sebacic acid-co-ricinoleic acid)IBA
08/2009
1CytotoxinsIBA
10/2008
1MicroRNAs (MicroRNA)IBA
10/2008
1P-GlycoproteinIBA
05/2007
1Cisplatin (Platino)FDA LinkGeneric
01/2007
1gefitinib (Iressa)FDA Link
01/2007
1NF-kappa B (NF-kB)IBA
12/2004
1Transcription Factors (Transcription Factor)IBA
12/2004
1TamoxifenFDA LinkGeneric
01/2003

Therapy/Procedure

3Heterologous Transplantation (Xenotransplantation)
05/2007 - 01/2007
1Drug Therapy (Chemotherapy)
10/2008
1Aftercare (After-Treatment)
01/2003
1Lasers (Laser)
01/2003
1Electrodes (Electrode)
01/2003