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Iichiro Shimomura Selected Research

Adiponectin

10/2008Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages.
05/2008Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha.
04/2008Nocturnal reduction in circulating adiponectin concentrations related to hypoxic stress in severe obstructive sleep apnea-hypopnea syndrome.
04/2008Prognostic value of adiponectin for cardiovascular disease and mortality.
01/2008Association of adiponectin and resistin with cardiovascular events in Korean patients with type 2 diabetes: The Korean atherosclerosis study (KAS) A 42-month prospective study.
01/2008Clinical significance of high-molecular weight form of adiponectin in male patients with coronary artery disease.
09/2007Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice.
11/2006[Metabolic syndrome and adiponectin]
09/2006Effect of adiponectin on murine colitis induced by dextran sulfate sodium.
06/2006Adiponectin replenishment ameliorates obesity-related hypertension.
09/2005Exacerbation of heart failure in adiponectin-deficient mice due to impaired regulation of AMPK and glucose metabolism.
01/2004Adiponectin and metabolic syndrome.
11/2002Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice.
10/2002Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis.
07/2002Diet-induced insulin resistance in mice lacking adiponectin/ACRP30.
07/2002Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome.
05/2002Serum adiponectin and leptin levels in patients with lipodystrophies.

Articles by Research Topic

Disease

7Syndrome
04/2008 - 07/2002
5Obesity
06/2006 - 04/2002
3Atherosclerosis (Atheroma)
10/2008 - 11/2002
2Fibrosis (Cirrhosis)
05/2008 - 09/2007
2Coronary Artery Disease (Coronary Atherosclerosis)
01/2008 - 04/2002
2Hepatocellular Carcinoma (Hepatoma)
10/2006 - 01/2006
2Stomach Neoplasms (Stomach Cancer)
06/2005 - 04/2005
2Lipodystrophy
07/2003 - 05/2002
2Insulin Resistance
07/2002 - 07/2002
1Obstructive Sleep Apnea
04/2008
1Cardiovascular Diseases (Cardiovascular Disease)
04/2008
1Albuminuria
09/2007
1Fistula
01/2007
1Aneurysm (Aneurysms)
01/2007
1Anoxia (Hypoxia)
10/2006
1Colitis
09/2006
1Hypertension (High Blood Pressure)
06/2006
1Breast Neoplasms (Breast Cancer)
03/2006
1Heart Failure
09/2005
1Werner Syndrome (Werner's Syndrome)
04/2005
1Hypertriglyceridemia
06/2003
1Pathologic Constriction (Stenosis)
10/2002

Drug/Important Bio-Agent (IBA)

17AdiponectinIBA
10/2008 - 05/2002
4AdipokinesIBA
06/2004 - 01/2003
2CholesterolIBA
10/2008 - 04/2005
2LeptinIBA
03/2006 - 05/2002
2Epidermal Growth Factor (EGF)IBA
06/2005 - 04/2005
2gefitinib (Iressa)FDA Link
06/2005 - 04/2005
2Interleukin-8 (Interleukin 8)IBA
06/2005 - 04/2005
1PPAR alphaIBA
05/2008
1Angiotensin IIIBA
05/2008
1Insulin (Novolin)FDA Link
03/2008
1ResistinIBA
01/2008
1Sirolimus (Rapamycin)FDA Link
01/2007
1Nicotinamide PhosphoribosyltransferaseIBA
10/2006
1GTP Phosphohydrolases (GTPases)IBA
10/2006
1Dextran SulfateIBA
09/2006
1Leptin ReceptorsIBA
03/2006
1Messenger RNA (mRNA)IBA
03/2006
1pamidronate (APD)FDA LinkGeneric
01/2006
1Glucose (Dextrose)FDA LinkGeneric
09/2005
1Glycerol KinaseIBA
08/2005
1liver X receptorIBA
06/2003
1ApolipoproteinsIBA
11/2002
1HormonesIBA
11/2002
1heparin-binding EGF-like growth factor (HB-EGF)IBA
04/2002

Therapy/Procedure

1Stents
01/2007