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Neng-Yao Shih Selected Research

Phosphopyruvate Hydratase (Enolase)

10/2015Anti-α-enolase is a prognostic marker in postoperative lung cancer patients.
5/2015Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells.
1/2013Surface α-enolase promotes extracellular matrix degradation and tumor metastasis and represents a new therapeutic target.
1/2011Overexpression of α-enolase correlates with poor survival in canine mammary carcinoma.
10/2010Generation and characterization of anti-alpha-enolase single-chain antibodies in chicken.
7/2010Anti-alpha-enolase autoantibodies are down-regulated in advanced cancer patients.
6/2010Increased expression of enolase alpha in human breast cancer confers tamoxifen resistance in human breast cancer cells.
10/2006Identification of alpha-enolase as an autoantigen in lung cancer: its overexpression is associated with clinical outcomes.

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Neng-Yao Shih Research Topics

Disease

12Neoplasms (Cancer)
08/2014 - 10/2006
6Lung Neoplasms (Lung Cancer)
10/2015 - 10/2006
3Breast Neoplasms (Breast Cancer)
01/2011 - 06/2010
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2015 - 07/2010
2Neoplasm Metastasis (Metastasis)
05/2015 - 01/2013
2Disease Progression
07/2010 - 01/2007
2Malignant Pleural Effusion
01/2007 - 10/2006
1B-Cell Lymphoma (Lymphoma, B Cell)
09/2015
1Non-Hodgkin Lymphoma (Lymphosarcoma)
09/2015
1Pancreatic Neoplasms (Pancreatic Cancer)
05/2015
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2013
1Neurodegenerative Diseases (Neurodegenerative Disease)
02/2011
1Carcinoma (Carcinomatosis)
01/2011
1Inflammation
07/2010
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
07/2010
1Head and Neck Neoplasms (Head and Neck Cancer)
06/2010
1Atherosclerosis
01/2009
1Thrombosis (Thrombus)
01/2009

Drug/Important Bio-Agent (IBA)

8Phosphopyruvate Hydratase (Enolase)IBA
10/2015 - 10/2006
3AntibodiesIBA
10/2015 - 10/2006
3Small Interfering RNA (siRNA)IBA
08/2014 - 06/2010
2PlasminogenIBA
05/2015 - 01/2013
2Messenger RNA (mRNA)IBA
08/2014 - 06/2010
2Estrogens (Estrogen)FDA Link
01/2011 - 06/2010
2AntigensIBA
07/2010 - 10/2006
17-hydroxy-6-methoxyphthalide (MA-1)IBA
09/2015
1Complementary DNA (cDNA)IBA
05/2015
1Serine Proteases (Serine Protease)IBA
05/2015
1FibrinolysinFDA Link
05/2015
1Proteins (Proteins, Gene)IBA
01/2013
1imatinib (Gleevec)FDA Link
01/2013
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
01/2013
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2013
1Carbon MonoxideIBA
01/2013
1LithiumIBA
02/2011
1IgYIBA
10/2010
1GoldIBA
07/2010
1Immunoglobulin A (IgA)IBA
07/2010
1AutoantibodiesIBA
07/2010
1Immunoglobulins (Immunoglobulin)IBA
07/2010
1Immunoglobulin G (IgG)IBA
07/2010
1Immunoglobulin M (IgM)IBA
07/2010
1TamoxifenFDA LinkGeneric
06/2010
14-hydroxytamoxifenIBA
06/2010
14,17 beta-dihydroxy-4-androstene-3-oneIBA
06/2010
1Chemokine CCL20IBA
06/2010
1Adenocarcinoma of lungIBA
05/2009
1VaccinesIBA
05/2009
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
01/2009
1Ticlopidine (Ticlid)FDA LinkGeneric
01/2009
1Transforming Growth Factor beta (TGF-beta)IBA
01/2007
1Protein Sorting Signals (Signal Peptide)IBA
01/2007
1Alanine (L-Alanine)FDA Link
01/2007

Therapy/Procedure

1Heterologous Transplantation (Xenotransplantation)
08/2014
1Lasers (Laser)
06/2010