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Jean C Shih Selected Research

Monoamine Oxidase (MAO)

2/2015Monoamine oxidase A inhibitor-near-infrared dye conjugate reduces prostate tumor growth.
7/2014Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis.
1/2014Monoamine oxidase B prompts mitochondrial and cardiac dysfunction in pressure overloaded hearts.
6/2012NMDARs mediate the role of monoamine oxidase A in pathological aggression.
5/2012De novo microdeletion of Xp11.3 exclusively encompassing the monoamine oxidase A and B genes in a male infant with episodic hypotonia: a genomics approach to personalized medicine.
1/2011Behavioral outcomes of monoamine oxidase deficiency: preclinical and clinical evidence.
5/2010A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage.
1/2010Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload.
11/2009Regulation of monoamine oxidase A by the SRY gene on the Y chromosome.
8/2009Glyceraldehyde-3-phosphate dehydrogenase-monoamine oxidase B-mediated cell death-induced by ethanol is prevented by rasagiline and 1-R-aminoindan.
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Jean C Shih Research Topics

Disease

5Neuroblastoma
05/2010 - 03/2005
3Neurodegenerative Diseases (Neurodegenerative Disease)
01/2011 - 05/2004
2Neoplasms (Cancer)
02/2015 - 07/2014
2Hypertrophy
01/2014 - 01/2010
2Heart Failure
01/2014 - 01/2010
2Antisocial Personality Disorder (Antisocial Personality)
06/2012 - 01/2011
2Mental Disorders (Mental Disorder)
01/2011 - 10/2008
2Parkinson Disease (Parkinson's Disease)
01/2011 - 10/2008
2Autistic Disorder (Autism)
01/2011 - 11/2009
2Glioblastoma (Glioblastoma Multiforme)
05/2010 - 07/2006
1Neoplasm Metastasis (Metastasis)
07/2014
1Anoxia (Hypoxia)
07/2014
1Prostatic Neoplasms (Prostate Cancer)
07/2014
1Heart Diseases (Heart Disease)
01/2014
1Pervasive Child Development Disorders
05/2013
1Muscle Hypotonia (Hypotonia)
05/2012
1Epilepsy (Aura)
10/2011
1Bipolar Disorder (Mania)
10/2011
1Impulse Control Disorders (Kleptomania)
01/2011
1Alcoholism (Alcohol Abuse)
05/2010
1Left Ventricular Dysfunction
01/2010
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
11/2009
1Mood Disorders (Mood Disorder)
10/2008
1Starvation
07/2006
1Breast Neoplasms (Breast Cancer)
07/2006
1Pheochromocytoma
05/2006
1AIDS-Related Complex (ARC)
11/2004
1Body Weight (Weight, Body)
09/2004

Drug/Important Bio-Agent (IBA)

18Monoamine Oxidase (MAO)IBA
02/2015 - 05/2004
3Serotonin (5 Hydroxytryptamine)IBA
05/2013 - 11/2004
2Phosphotransferases (Kinase)IBA
01/2014 - 07/2006
2Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2014 - 01/2010
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2014 - 01/2010
1Clorgyline (Clorgiline)IBA
02/2015
1Transcription Factors (Transcription Factor)IBA
07/2014
1Neurotransmitter Agents (Neurotransmitter)IBA
07/2014
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2014
1AminesIBA
07/2014
1Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
10/2011
1IsoenzymesIBA
01/2011
1Ethanol (Ethyl Alcohol)IBA
05/2010
1Adrenergic Receptors (Adrenergic Receptor)IBA
01/2010
1CatecholaminesIBA
01/2010
1Messenger RNA (mRNA)IBA
06/2009
1Tretinoin (Retinoic Acid)FDA LinkGeneric
06/2009
1Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA
10/2008
1Dexamethasone (Maxidex)FDA LinkGeneric
07/2006
1MetriboloneIBA
07/2006
1LuciferasesIBA
07/2006
1Caspase 3 (Caspase-3)IBA
07/2006
1ERRalpha estrogen-related receptorIBA
07/2006
1PC 12IBA
05/2006
1Tryptophan HydroxylaseIBA
11/2004

Therapy/Procedure

2Heterologous Transplantation (Xenotransplantation)
02/2015 - 07/2014
1Individualized Medicine
05/2012