Charles N Serhan Selected Research

Inflammation

08/2008	Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A(4) to promote the resolution of allergic airway inflammation.
03/2008	Resolvin E1 metabolome in local inactivation during inflammation-resolution.
01/2008	Anesthetics impact the resolution of inflammation.
11/2007	Resolvin E1 regulates inflammation at the cellular and tissue level and restores tissue homeostasis in vivo.
07/2007	Aspirin-triggered lipoxins override the apoptosis-delaying action of serum amyloid A in human neutrophils: a novel mechanism for resolution of inflammation.
06/2007	Resolvin E1 and protectin D1 activate inflammation-resolution programmes.
03/2007	Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation.
01/2007	Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness.
08/2006	Lipoxins and new lipid mediators in the resolution of inflammation.
10/2005	Novel polyisoprenyl phosphates block phospholipase D and human neutrophil activation in vitro and murine peritoneal inflammation in vivo.
09/2005	Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution.
02/2004	Is C-reactive protein an inflammation opsonin that signals colon cancer risk?
12/2003	Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators.
04/2003	Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation.
09/2002	Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).
08/2002	Lipoxins and aspirin-triggered 15-epi-lipoxin biosynthesis: an update and role in anti-inflammation and pro-resolution.
01/2002	Lipid-derived mediators in endogenous anti-inflammation and resolution: lipoxins and aspirin-triggered 15-epi-lipoxins.

Articles by Research Topic

Disease

17	Inflammation 08/2008 - 01/2002
2	Asthma (Bronchial Asthma) 01/2007 - 05/2003
2	Colitis 07/2006 - 05/2005
2	Osteoporosis 12/2004 - 04/2004
1	Infection 04/2007
1	Pain (Aches) 02/2007
1	Melanoma (Melanoma, Malignant) 08/2006
1	Alzheimer Disease (Alzheimer's Disease) 10/2005
1	Periodontal Diseases (Periodontal Disease) 12/2004
1	Colonic Neoplasms (Colon Cancer) 02/2004
1	Tissue Adhesions 01/2002

Drug/Important Bio-Agent (IBA)

9	LipoxinsIBA 08/2008 - 01/2002
7	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 07/2007 - 01/2002
6	5S,12R,18R- trihydroxy- 6Z,8E,10E,14Z,16E- eicosapentaenoic acidIBA 08/2008 - 05/2005
3	neuroprotectin D1IBA 06/2007 - 10/2005
2	lipoxin A4IBA 08/2008 - 01/2002
1	Interleukin-23 (Interleukin 23)IBA 08/2008
1	Interferon-gamma (Interferon, gamma)IBA 08/2008
1	Anesthetics (Anesthetic Agents)IBA 01/2008
1	Serum Amyloid A Protein (Serum Amyloid A)IBA 07/2007
1	Thromboxane A2 (A2, Thromboxane)IBA 04/2007
1	Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA 03/2007
1	Essential Fatty AcidsIBA 08/2006
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)FDA Link 07/2006
1	Phospholipase DIBA 10/2005
1	Polyisoprenyl PhosphatesIBA 10/2005
1	sym-trinitrobenzeneIBA 05/2005
1	Eicosapentaenoic AcidIBA 05/2005
1	Lipoxygenase (Lipoxygenase-1)IBA 12/2004
1	C-Reactive ProteinIBA 02/2004
1	Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA 12/2003
1	AutacoidsIBA 04/2003

Therapy/Procedure

2	Therapeutics 12/2004 - 04/2004