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Frank W Sellke Selected Research

Myocardial Reperfusion Injury

3/2009Thrombin fragment (TP508) decreases myocardial infarction and apoptosis after ischemia reperfusion injury.
10/2004Reduction of myocardial reperfusion injury by aprotinin after regional ischemia and cardioplegic arrest.
3/2004Mitogen-activated protein kinase pathways and cardiac surgery.
10/2002A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs.

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Frank W Sellke Research Topics

Disease

56Myocardial Ischemia (Ischemic Heart Diseases)
01/2016 - 02/2002
45Ischemia
02/2015 - 07/2002
22Hypercholesterolemia
01/2016 - 08/2004
16Coronary Artery Disease (Coronary Atherosclerosis)
05/2013 - 02/2003
14Reperfusion Injury
01/2015 - 02/2002
7Stroke (Strokes)
11/2012 - 12/2008
7Coronary Disease (Coronary Heart Disease)
05/2012 - 08/2004
5Fibrosis (Cirrhosis)
11/2014 - 10/2011
5Inflammation
06/2014 - 01/2007
5B-Cell Lymphoma (Lymphoma, B Cell)
09/2013 - 03/2009
5Myocardial Infarction
01/2011 - 02/2002
4Cardiovascular Diseases (Cardiovascular Disease)
11/2014 - 08/2011
4Hemorrhage
05/2014 - 01/2007
4Hypertension (High Blood Pressure)
03/2012 - 01/2003
4Infarction
10/2011 - 08/2003
4Anoxia (Hypoxia)
07/2009 - 12/2003
4Myocardial Reperfusion Injury
03/2009 - 10/2002
3Diabetes Mellitus
08/2011 - 09/2004
3Thrombosis (Thrombus)
03/2011 - 05/2005
2Necrosis
03/2014 - 06/2009
2Wound Infection (Wound Infections)
11/2012 - 09/2005
2Weight Gain
03/2012 - 07/2009
2Shock
04/2010 - 03/2009
2Heart Arrest (Cardiac Arrest)
01/2010 - 10/2009
2Edema
07/2009 - 08/2005
2Delirium
01/2009 - 02/2008
2Brain Injuries (Brain Injury)
10/2007 - 10/2006
2Pre-Eclampsia (Preeclampsia)
06/2006 - 03/2003
2Coronary Occlusion
05/2006 - 12/2005
2Lung Injury
11/2003 - 07/2003
1Atrial Fibrillation
05/2015
1Lymphoma (Lymphomas)
06/2014
1Cardiac Tamponade
05/2014
1Cardiomegaly (Heart Hypertrophy)
03/2014

Drug/Important Bio-Agent (IBA)

33ameroidIBA
11/2015 - 03/2003
11CholesterolIBA
02/2015 - 04/2008
11resveratrolIBA
01/2015 - 06/2009
11Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2014 - 03/2003
8Proteins (Proteins, Gene)IBA
08/2015 - 07/2002
7Arginine (L-Arginine)FDA Link
01/2010 - 04/2004
7Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2010 - 10/2002
6ThrombinFDA Link
09/2010 - 05/2005
5atorvastatin (Lipitor)FDA Link
02/2015 - 07/2006
5Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
05/2012 - 02/2003
5Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
04/2008 - 07/2002
5Aprotinin (Trasylol)FDA Link
01/2007 - 10/2004
4glucuronyl glucosamine glycan sulfate (Vessel)IBA
02/2015 - 11/2011
4Hydrogen Sulfide (Sulfide, Hydrogen)IBA
01/2015 - 05/2008
4Neuropeptide YIBA
10/2013 - 12/2010
4Insulin (Novolin)FDA Link
08/2013 - 09/2005
4Carbon MonoxideIBA
09/2011 - 01/2007
4rusalatide acetate (Chrysalin)IBA
09/2010 - 03/2009
3Metformin (Glucophage)FDA LinkGeneric
11/2014 - 03/2012
3Poly Adenosine Diphosphate RiboseIBA
09/2013 - 02/2002
3Caspase 3 (Caspase-3)IBA
09/2013 - 04/2004
3CytokinesIBA
05/2008 - 02/2008
2CalpainIBA
01/2016 - 08/2015
2Biological Markers (Surrogate Marker)IBA
05/2015 - 10/2006
2LigandsIBA
09/2014 - 01/2014
2Notch ReceptorsIBA
09/2014 - 01/2014
2Adenosine Monophosphate (AMP)IBA
06/2014 - 07/2009
2Troponin T (T, Troponin)IBA
01/2012 - 10/2011
2Naproxen (Naprosyn)FDA LinkGeneric
01/2012 - 09/2011
2Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
01/2012 - 11/2010
2celecoxib (Celebrex)FDA Link
01/2012 - 09/2011
2Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
10/2011 - 04/2010
2Messenger RNA (mRNA)IBA
10/2011 - 07/2009
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
09/2011 - 11/2010
2erucylphosphocholineIBA
09/2010 - 05/2008
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
08/2010 - 08/2003
2Phosphotransferases (Kinase)IBA
04/2010 - 01/2008
2Crystallins (Crystallin)IBA
10/2009 - 12/2007
2HSP27 Heat-Shock ProteinsIBA
10/2009 - 12/2007
2Evans Blue (Blue, Evans)FDA Link
10/2009 - 05/2008
2EndostatinsIBA
02/2009 - 02/2006
2Coenzyme A (CoA)IBA
01/2008 - 07/2006
2Serine Proteases (Serine Protease)IBA
01/2007 - 10/2004
2Mitogen-Activated Protein KinasesIBA
03/2004 - 11/2003
2OxygenIBA
07/2003 - 10/2002
1calpain inhibitor IIIIBA
01/2016
1Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
05/2015
1Proliferating Cell Nuclear Antigen (PCNA)IBA
03/2015
1CollagenIBA
11/2014
1Protein Kinases (Protein Kinase)IBA
06/2014
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
06/2014
1polybutyl methacrylate (PBMA)IBA
06/2014
1polylactic acid-polyglycolic acid copolymer (PLGA)IBA
06/2014
1Hemoglobins (Hemoglobin)IBA
05/2014

Therapy/Procedure

12Cardiopulmonary Bypass (Heart-Lung Bypass)
10/2013 - 08/2003
8Induced Heart Arrest (Cardioplegia)
01/2008 - 08/2003
7Coronary Artery Bypass (Coronary Artery Bypass Surgery)
05/2012 - 09/2004
4Stents
06/2014 - 03/2011
4Transplants (Transplant)
04/2012 - 01/2003
4Anesthesia
01/2010 - 12/2008
4Resuscitation
01/2010 - 12/2008
4Critical Care
01/2010 - 12/2008
3Tissue Therapy (Cell Therapy)
01/2011 - 04/2008
2Catheters
05/2012 - 06/2006
2Blood Transfusion (Blood Transfusions)
04/2012 - 03/2010
1Chest Tubes (Chest Tube)
05/2014