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Martin G Schwacha Selected Research

Estrogens (Estrogen)

10/2008Mechanism of estrogen-mediated improvement in cardiac function after trauma-hemorrhage: p38-dependent normalization of cardiac Akt phosphorylation and glycogen levels.
08/2008Estrogen ameliorates trauma-hemorrhage-induced lung injury via endothelial nitric oxide synthase-dependent activation of protein kinase G.
06/2008Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: p38 MAPK-dependent upregulation of HO-1.
10/2007Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation.
09/2007Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway.
06/2007Role of p38 mitogen-activated protein kinase pathway in estrogen-mediated cardioprotection following trauma-hemorrhage.
06/2007The PI3K/Akt pathway mediates the nongenomic cardioprotective effects of estrogen following trauma-hemorrhage.
05/2007Downregulation of migration inhibitory factor is critical for estrogen-mediated attenuation of lung tissue damage following trauma-hemorrhage.
05/2007Downregulation of TLR4-dependent ATP production is critical for estrogen-mediated immunoprotection in Kupffer cells following trauma-hemorrhage.
04/2007G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage.
01/2007Tissue compartment-specific role of estrogen receptor subtypes in immune cell cytokine production following trauma-hemorrhage.
01/2006Flutamide restores cardiac function after trauma-hemorrhage via an estrogen-dependent pathway through upregulation of PGC-1.
05/2002Estrogen pretreatment protects males against hypoxia-induced immune depression.

Articles by Research Topic

Disease

43Wounds and Injuries (Trauma)
10/2008 - 01/2002
40Hemorrhage
10/2008 - 01/2002
3Poisoning
05/2008 - 08/2006
3Burns
05/2008 - 07/2006
3Sepsis (Septicemia)
08/2006 - 01/2002
2Anoxia (Hypoxia)
09/2006 - 05/2002
2Hemorrhagic Shock
12/2004 - 12/2003

Drug/Important Bio-Agent (IBA)

13Estrogens (Estrogen)FDA Link
10/2008 - 05/2002
6Estradiol (Estrace)FDA LinkGeneric
06/2008 - 04/2003
4p38 Mitogen-Activated Protein KinasesIBA
06/2008 - 09/2006
3Flutamide (Eulexin)FDA LinkGeneric
08/2008 - 01/2006
3Estrogen Receptor betaIBA
09/2006 - 02/2006
2Protein Kinases (Protein Kinase)IBA
03/2008 - 06/2007
2Peroxidase (Myeloperoxidase)IBA
09/2007 - 02/2006
2Endothelin-1 (Endothelin 1)IBA
01/2007 - 09/2004
2Interleukin-6 (Interleukin 6)IBA
09/2006 - 12/2004
2AndrostenediolIBA
08/2006 - 02/2005
2Estrogen ReceptorsIBA
05/2006 - 03/2003
2Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA
07/2005 - 12/2003
2Interleukin-10 (Interleukin 10)IBA
06/2004 - 05/2004
2Prolactin Receptors (Prolactin Receptor)IBA
12/2003 - 05/2002
2Gonadal Steroid Hormones (Sex Hormones)IBA
04/2002 - 01/2002
1GlycogenIBA
10/2008
1Chemokine CCL3IBA
08/2008
1Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA
08/2008
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
08/2008
1neutrophil cytosol factor 67KIBA
05/2008
1Heme Oxygenase-1IBA
05/2008
1Protein Tyrosine PhosphatasesIBA
05/2008
1Estrogen Receptor alphaIBA
01/2008
1Mitogen-Activated Protein KinasesIBA
07/2007
1Adenosine Triphosphate (ATP)IBA
05/2007
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
04/2007
1GTP-Binding Proteins (G-Protein)IBA
04/2007
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
03/2007
1Toll-Like Receptors (Toll-Like Receptor)IBA
03/2007
1Lidocaine (Xylocaine)FDA LinkGeneric
11/2006
1src-Family KinasesIBA
09/2006
1Interleukin-18 (Interleukin 18)IBA
08/2006
1CorticosteroneIBA
08/2006
1Analgesics (Analgesic Drugs)IBA
07/2006
1Heat-Shock Proteins (Heat-Shock Protein)IBA
03/2006
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
02/2005

Therapy/Procedure

1Resuscitation
10/2008