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Ernesto L Schiffrin Selected Research

Inflammation

08/2008The flame that lights the fire: oxidative stress, inflammation, and renal damage in angiotensin II-induced hypertension.
06/2008Vascular inflammation in absence of blood pressure elevation in transgenic murine model overexpressing endothelin-1 in endothelial cells.
04/2007Resistance artery remodeling in deoxycorticosterone acetate-salt hypertension is dependent on vascular inflammation: evidence from m-CSF-deficient mice.
11/2005Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy.
10/2005Reduced vascular remodeling, endothelial dysfunction, and oxidative stress in resistance arteries of angiotensin II-infused macrophage colony-stimulating factor-deficient mice: evidence for a role in inflammation in angiotensin-induced vascular injury.
02/2005Dual angiotensin-converting enzyme/neutral endopeptidase inhibition on cardiac and renal fibrosis and inflammation in DOCA-salt hypertensive rats.
11/2004Long-term effects of the PPAR gamma activator pioglitazone on cardiac inflammation in stroke-prone spontaneously hypertensive rats.
02/2004PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats.
05/2003Inflammation and vascular hypertrophy induced by angiotensin II: role of NADPH oxidase-derived reactive oxygen species independently of blood pressure elevation?
12/2002PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation.
05/2002Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptor-gamma.
02/2002Fibrosis, matrix metalloproteinases, and inflammation in the heart of DOCA-salt hypertensive rats: role of ET(A) receptors.

Articles by Research Topic

Disease

29Hypertension (High Blood Pressure)
09/2008 - 01/2002
12Inflammation
08/2008 - 02/2002
8Stroke (Strokes)
12/2006 - 01/2002
7Fibrosis (Cirrhosis)
11/2005 - 02/2002
3Hypertrophy
11/2005 - 02/2002
1Cardiomegaly (Heart Hypertrophy)
10/2008
1Heart Failure
03/2008
1Hyperglycemia
06/2007
1Hyperaldosteronism (Conn Syndrome)
02/2005
1Tissue Adhesions
04/2004
1Diabetes Complications
04/2004
1Proteinuria
03/2004
1Vascular Diseases (Vascular Disease)
02/2003
1Diabetic Nephropathies (Diabetic Nephropathy)
03/2002

Drug/Important Bio-Agent (IBA)

15Angiotensin IIIBA
08/2008 - 05/2002
7Endothelins (Endothelin)IBA
06/2005 - 01/2003
6AldosteroneIBA
03/2008 - 02/2002
5Endothelin-1 (Endothelin 1)IBA
09/2008 - 02/2002
5Desoxycorticosterone (DOCA)FDA Link
04/2007 - 02/2002
4PPAR alphaIBA
02/2004 - 12/2002
3ReninIBA
03/2008 - 03/2004
3PPAR gammaIBA
06/2007 - 05/2002
3AngiotensinsIBA
10/2005 - 03/2002
2Reactive Oxygen Species (Oxygen Radicals)IBA
06/2008 - 05/2003
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
08/2007 - 10/2003
2Macrophage Colony-Stimulating FactorIBA
04/2007 - 10/2005
2Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2006 - 04/2004
2PerindoprilFDA Link
09/2005 - 02/2002
2NADPH Oxidase (NAD(P)H oxidase)IBA
01/2005 - 05/2003
1ThioredoxinsIBA
10/2008
1Insulin (Novolin)FDA Link
06/2007
1Protein Kinases (Protein Kinase)IBA
12/2006
1rho-Associated KinasesIBA
05/2005
1Type 2 Angiotensin ReceptorIBA
05/2005
1MagnesiumIBA
02/2005
1CalciumIBA
02/2005
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
02/2005
1Neprilysin (Neutral Endopeptidase)IBA
02/2005
1pioglitazone (Actos)FDA Link
11/2004
1eplerenone (Inspra)FDA LinkGeneric
06/2004
1Procetofen (CiL)FDA LinkGeneric
02/2004
1PeptidesIBA
01/2004
1Natriuretic PeptidesIBA
01/2004
1LeptinIBA
01/2004
1AdrenomedullinIBA
01/2004
1Follicle Stimulating Hormone (Follitropin)IBA
10/2003
1Superoxides (Superoxide)IBA
10/2003
1Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA
08/2003
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
08/2002
1CollagenIBA
06/2002
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
06/2002
1Endothelin A ReceptorIBA
06/2002
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
06/2002
1Matrix MetalloproteinasesIBA
02/2002
1Superoxide DismutaseIBA
01/2002