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Thomas S Scanlan Selected Research

GC 1 compound

4/2007Thyroid hormone receptor beta-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats.
7/2006The thyroid hormone receptor-beta agonist GC-1 induces cell proliferation in rat liver and pancreas.
7/2005Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.
2/2005The thyroid hormone receptor beta-specific agonist GC-1 selectively affects the bone development of hypothyroid rats.
4/2004Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: selective actions relative to 3,5,3'-triiodo-L-thyronine.
3/2004Aberrant maturation of astrocytes in thyroid hormone receptor alpha 1 knockout mice reveals an interplay between thyroid hormone receptor isoforms.

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Thomas S Scanlan Research Topics

Disease

4Body Weight (Weight, Body)
10/2010 - 04/2004
4Hypothermia
06/2009 - 02/2006
3Obesity
04/2007 - 04/2004
2Insulin Resistance
01/2012 - 04/2010
2Ischemia
08/2011 - 09/2007
2Hyperglycemia
06/2009 - 12/2007
2Bradycardia
06/2009 - 04/2008
2Hyperthyroidism
07/2006 - 01/2003
2Hypothyroidism
02/2005 - 03/2004
1Heart Failure
01/2012
1Endometriosis (Adenomyosis)
07/2009
1Endometrial Neoplasms (Endometrial Cancer)
07/2009
1Choriocarcinoma
07/2009
1Cardiac Arrhythmias (Arrythmia)
11/2008
1Hyperinsulinism (Hyperinsulinemia)
12/2007
1Stroke (Strokes)
09/2007
1Breast Neoplasms (Breast Cancer)
02/2007
1Uterine Neoplasms (Uterine Cancer)
02/2007
1Hot Flashes
02/2007
1Neoplasms (Cancer)
02/2007
1Brain Ischemia (Cerebral Ischemia)
09/2006
1Dyslipidemias (Dyslipidemia)
07/2005
1Hypercholesterolemia
07/2005
1Tachycardia (Tachyarrhythmias)
04/2004
1Endocrine System Diseases (Endocrine Diseases)
12/2003
1Thyrotoxicosis
11/2003

Drug/Important Bio-Agent (IBA)

6GC 1 compoundIBA
04/2007 - 03/2004
43-iodothyronamineIBA
08/2011 - 02/2006
3HormonesIBA
04/2008 - 01/2003
2Estrogens (Estrogen)FDA Link
07/2009 - 02/2007
2thyronamineIBA
06/2009 - 09/2007
2Thyroxine (Levothyroxine)FDA LinkGeneric
04/2008 - 09/2007
2CholesterolIBA
07/2005 - 04/2004
2Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA
04/2004 - 01/2003
2Thyroid Hormone Receptors beta (TR beta)IBA
03/2004 - 11/2003
1Thyroid HormonesIBA
01/2012
1triphenyltetrazoliumIBA
08/2011
1Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
08/2011
1Aminobutyric Acids (Aminobutyric Acid)IBA
10/2010
1Prednisolone (Predate)FDA LinkGeneric
04/2010
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
07/2009
1Protein Kinases (Protein Kinase)IBA
07/2009
1TamoxifenFDA LinkGeneric
07/2009
1Estradiol Congeners (Synthetic Estrogens)IBA
07/2009
1Amiodarone (Amiodarona)FDA LinkGeneric
11/2008
1Insulin (Novolin)FDA Link
12/2007
1Glucose (Dextrose)FDA LinkGeneric
12/2007
1Neuroprotective AgentsIBA
09/2007
1Triiodothyronine (Liothyronine)FDA LinkGeneric
04/2007
1Cyclin D1IBA
02/2007
1Estrogen Receptor alphaIBA
02/2007
1LigandsIBA
02/2007
1Estrogen Receptor betaIBA
02/2007
1Phosphotransferases (Kinase)IBA
09/2006
1Triglycerides (Triacylglycerol)IBA
07/2005
1Insulin-Like Growth Factor I (IGF-1)IBA
02/2005
1Lipoprotein(a)IBA
04/2004
1LDL CholesterolIBA
04/2004
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
12/2003

Therapy/Procedure

1Injections
04/2007
1Heterologous Transplantation (Xenotransplantation)
02/2007
1Drug Therapy (Chemotherapy)
04/2004
1Therapeutics
12/2003