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Mitsunobu Sato Selected Research

Cyclin-Dependent Kinase Inhibitor p27

9/2005Basic investigation on the development of molecular targeting therapy against cyclin-dependent kinase inhibitor p27Kip1 in head and neck cancer cells.
8/2004Characteristics of antitumor activity of mutant type p27Kip1 gene in an oral cancer cell line.
12/2003Overexpression of tuberous sclerosis complex 2 exerts antitumor effect on oral cancer cell lines.
5/2003Effect of p27Kip1 on the ability of invasion and metastasis of an oral cancer cell line.
10/2002Overexpression of p27(Kip1) induces growth arrest and apoptosis in an oral cancer cell line.

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Mitsunobu Sato Research Topics

Disease

34Neoplasms (Cancer)
03/2013 - 03/2002
17Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/2013 - 07/2002
8Mouth Neoplasms (Oral Cancer)
07/2005 - 10/2002
6Neoplasm Metastasis (Metastasis)
12/2010 - 05/2003
5Head and Neck Neoplasms (Head and Neck Cancer)
10/2005 - 07/2002
4Salivary Gland Neoplasms (Salivary Gland Cancer)
10/2004 - 03/2002
2Adenocarcinoma
04/2006 - 11/2002
2Pleomorphic Adenoma
04/2006 - 07/2002
2Carcinoma (Carcinomatosis)
03/2004 - 03/2002
1Body Weight (Weight, Body)
07/2007
1Atopic Dermatitis (Atopic Eczema)
09/2006
1Anorexia
06/2006
1Adenoid Cystic Carcinoma (Cylindroma)
04/2006
1Hydrocephalus (Hydrocephaly)
02/2006
1Xerostomia
03/2005
1Fibrosarcoma
11/2004
1Tuberous Sclerosis (Bourneville's Disease)
12/2003
1Lewis Lung Carcinoma
02/2003

Drug/Important Bio-Agent (IBA)

13PicibanilIBA
07/2013 - 11/2002
7Messenger RNA (mRNA)IBA
06/2006 - 03/2002
5Cyclin-Dependent Kinase Inhibitor p27IBA
09/2005 - 10/2002
4Fluorouracil (Carac)FDA LinkGeneric
07/2013 - 03/2004
4Phosphotransferases (Kinase)IBA
09/2005 - 08/2004
3Chemokine CXCL12IBA
07/2007 - 11/2003
3lipoteichoic acidIBA
09/2006 - 11/2002
3DNA (Deoxyribonucleic Acid)IBA
03/2006 - 02/2003
3Toll-Like Receptors (Toll-Like Receptor)IBA
10/2005 - 02/2003
3S-Phase Kinase-Associated Proteins (Skp1 Protein)IBA
09/2005 - 05/2005
3CyclinsIBA
09/2005 - 08/2004
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2007 - 12/2005
2Nitric Oxide (Nitrogen Monoxide)FDA Link
05/2006 - 07/2004
2Complementary DNA (cDNA)IBA
04/2006 - 12/2003
2Carrier Proteins (Binding Protein)IBA
03/2006 - 09/2005
2UbiquitinIBA
02/2006 - 07/2005
2Interleukin-8 (Interleukin 8)IBA
12/2005 - 03/2004
2NF-kappa B (NF-kB)IBA
12/2005 - 03/2004
2Caspase 3 (Caspase-3)IBA
07/2005 - 06/2004
2Interleukin-6 (Interleukin 6)IBA
04/2005 - 03/2004
2CytokinesIBA
04/2005 - 11/2002
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2005 - 11/2002
2titanium silicide (TS-1)IBA
11/2004 - 10/2004
2Toll-Like Receptor 4IBA
11/2004 - 08/2004
2Caspase 8 (Caspase-8)IBA
10/2004 - 06/2004
2PPAR gammaIBA
12/2003 - 03/2002
2LigandsIBA
12/2003 - 03/2002
1InterferonsIBA
03/2013
1metaperiodate (periodate)IBA
12/2010
1pectinIBA
12/2010
1HydrogelsIBA
12/2010
1tranilast (N 5')IBA
01/2008
1JM 3100FDA Link
07/2007
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
02/2007
1Thymidylate SynthaseIBA
06/2006
1BilirubinIBA
06/2006
1Arginine (L-Arginine)FDA Link
05/2006
1Nitric Oxide Synthase (NO Synthase)IBA
05/2006
1superoxide dismutase 2IBA
02/2006
1Microtubule ProteinsIBA
02/2006
1Lamin Type A (Lamin A)IBA
02/2006
1myosin light chain 2IBA
02/2006
1plastinIBA
02/2006
1Proteins (Proteins, Gene)IBA
02/2006
1Annexin A3IBA
02/2006
1MM Form Creatine KinaseIBA
02/2006
1vesnarinoneIBA
12/2005
1CaspasesIBA
10/2005
1Interleukin-10 (Interleukin 10)IBA
10/2005
1Transforming Growth Factor beta (TGF-beta)IBA
10/2005
1ChemokinesIBA
09/2005
12-nitroimidazole acetamideIBA
09/2005
1Ubiquitin-Protein Ligase ComplexesIBA
07/2005
1RANK LigandIBA
04/2005
1Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA
04/2005
1OsteoprotegerinIBA
04/2005
1YM 529IBA
04/2005
1Parathyroid Hormone-Related ProteinIBA
04/2005
1Deoxycytidine (CDR)IBA
03/2005
1Aquaporin 5IBA
03/2005
1U 0126 (UO 126)IBA
12/2004
1wortmanninIBA
12/2004
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
12/2004
1Protein Kinases (Protein Kinase)IBA
12/2004
1OxygenIBA
10/2004
1NitrogenIBA
10/2004
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
07/2004
1Caspase 9IBA
06/2004
1Cytochromes c (Cytochrome c)IBA
06/2004
1Cisplatin (Platino)FDA LinkGeneric
06/2004
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2004
1tuberous sclerosis complex 2 protein (tuberin)IBA
12/2003
1ThiazolidinedionesIBA
12/2003
1Interferon-gamma (Interferon, gamma)IBA
05/2003
1Cadherins (E-Cadherin)IBA
05/2003
1cepharanthineIBA
03/2003

Therapy/Procedure

5Radiotherapy
07/2013 - 03/2004
4Heterologous Transplantation (Xenotransplantation)
09/2005 - 08/2004
3Drug Therapy (Chemotherapy)
11/2004 - 03/2004
2Oral Administration
11/2004 - 10/2004
1Intraperitoneal Injections
02/2003
1Immunotherapy
02/2003