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Hiroyuki Sasamura Selected Research

Angiotensins

10/2015Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria.
12/2013Feasibility of regression of hypertension using contemporary antihypertensive agents.
5/2012Vaccination against the angiotensin type 1 receptor for the prevention of L-NAME-induced nephropathy.
1/2012Regression of atherosclerosis in apolipoprotein E-deficient mice is feasible using high-dose angiotensin receptor blocker, candesartan.
9/2011[Angiotensin receptor vaccines].
1/2011[Hypertension and arteriosclerosis].
7/2010Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2.
8/2009Prevention and regression of hypertension: role of renal microvascular protection.
1/2009"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
10/2008The short treatment with the angiotensin receptor blocker candesartan surveyed by telemedicine (STAR CAST) study: rationale and study design.
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Hiroyuki Sasamura Research Topics

Disease

14Hypertension (High Blood Pressure)
10/2014 - 08/2002
5Proteinuria
10/2015 - 10/2002
4Albuminuria
10/2015 - 01/2010
4Hypertrophy
01/2011 - 01/2009
2Kidney Diseases (Kidney Disease)
10/2015 - 07/2010
2Stroke (Strokes)
04/2015 - 08/2002
2Purpura
01/2010 - 01/2007
2Diabetic Nephropathies (Diabetic Nephropathy)
01/2008 - 01/2007
2Neoplasms (Cancer)
01/2007 - 10/2004
2Chronic Kidney Failure (Chronic Renal Failure)
01/2007 - 10/2003
2Fibrosis (Cirrhosis)
04/2004 - 10/2003
2Nephrosclerosis
10/2002 - 08/2002
1Atherosclerotic Plaque (Atheroma)
01/2012
1Atherosclerosis
01/2012
1Hemorrhage
01/2010
1IGA Glomerulonephritis (IGA Nephropathy)
01/2010
1Acute Kidney Injury (Acute Renal Failure)
01/2010
1POEMS Syndrome (Syndrome, POEMS)
05/2008
1Hematologic Diseases (Blood Diseases)
05/2008
1Renal Cell Carcinoma (Grawitz Tumor)
01/2007
1Systemic Vasculitis
01/2007
1Abdominal Pain (Pain, Abdominal)
01/2007
1Inflammation
01/2007
1Hematuria
01/2007
1Nephrotic Syndrome (Syndrome, Nephrotic)
01/2007
1Edema
01/2007
1Arthralgia (Joint Pain)
01/2007
1Amyloid Plaque
01/2007
1Hyperaldosteronism (Conn Syndrome)
10/2004
1Hypersensitivity (Allergy)
10/2004
1Vascular System Injuries
04/2004

Drug/Important Bio-Agent (IBA)

14AngiotensinsIBA
10/2015 - 08/2002
5ReninIBA
10/2015 - 01/2011
4Angiotensin IIIBA
10/2015 - 01/2007
4Doxorubicin (Adriamycin)FDA LinkGeneric
10/2015 - 01/2010
4candesartanIBA
12/2013 - 07/2006
3Antihypertensive Agents (Antihypertensives)IBA
12/2013 - 05/2006
3VaccinesIBA
09/2012 - 09/2011
2nephrinIBA
10/2015 - 06/2014
2Nifedipine (Adalat)FDA LinkGeneric
12/2013 - 10/2008
2NG-Nitroarginine Methyl Ester (L-NAME)IBA
05/2012 - 01/2007
2CholesterolIBA
01/2012 - 01/2007
2BiglycanIBA
01/2012 - 04/2004
2Immunoglobulin A (IgA)IBA
01/2010 - 01/2007
2Calcium Channels (Calcium Channel)IBA
10/2008 - 05/2006
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
05/2006 - 10/2002
1GKLF proteinIBA
10/2015
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
04/2015
1Angiotensin Receptor AntagonistsIBA
04/2015
1Angiotensin IIBA
09/2012
1Proteoglycans (Proteoglycan)IBA
01/2012
1Apolipoproteins E (ApoE)IBA
01/2012
1ApolipoproteinsIBA
01/2012
1Matrix MetalloproteinasesIBA
01/2010
1Doxycycline (Vibramycin)FDA LinkGeneric
01/2010
1GelatinasesIBA
01/2010
1Collagenases (Collagenase)FDA Link
01/2010
1Collagen Type IV (Type IV Collagen)IBA
01/2010
1Matrix Metalloproteinase 13IBA
01/2009
1CytokinesIBA
05/2008
1Serum AlbuminIBA
01/2007
1glucuronyl glucosamine glycan sulfate (Vessel)IBA
01/2007
1Antigen-Antibody Complex (Immune Complex)IBA
01/2007
1Potassium PermanganateIBA
01/2007
1Hematoxylin (Haematoxylon)IBA
01/2007
1Nitric Oxide Synthase (NO Synthase)IBA
01/2007
1Eosine Yellowish-(YS) (Eosin)IBA
01/2007
1Congo RedIBA
01/2007
1Primary amyloidosisIBA
01/2007
1EnalaprilFDA LinkGeneric
05/2006
1Amlodipine (Norvasc)FDA LinkGeneric
05/2006
1GadoliniumIBA
10/2004
1Contrast MediaIBA
10/2004
1HormonesIBA
10/2004
1IodineIBA
10/2004
1A-factor (Streptomyces)IBA
04/2004
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
10/2003

Therapy/Procedure

1Aftercare (After-Treatment)
01/2012
1Nephrectomy
01/2007
1Renal Dialysis (Hemodialysis)
01/2007