William J Sandborn Selected Research

Inflammatory Bowel Diseases (Inflammatory Bowel Disease)

10/2022	CORE-IBD: A Multidisciplinary International Consensus Initiative to Develop a Core Outcome Set for Randomized Controlled Trials in Inflammatory Bowel Disease.
5/2022	Effectiveness and Safety of Biologic Therapy in Hispanic Vs Non-Hispanic Patients With Inflammatory Bowel Diseases: A CA-IBD Cohort Study.
1/2022	Comparative Risk of Serious Infections With Tumor Necrosis Factor α Antagonists vs Vedolizumab in Patients With Inflammatory Bowel Diseases.
1/2022	Risk of Malignancy with Vedolizumab Versus Tumor Necrosis Factor-α Antagonists in Patients with Inflammatory Bowel Diseases.
1/2022	Real-world multicentre observational study including population pharmacokinetic modelling to evaluate the exposure-response relationship of vedolizumab in inflammatory bowel disease: ERELATE Study.
1/2022	Artificial intelligence-rationalized balanced PPARα/γ dual agonism resets dysregulated macrophage processes in inflammatory bowel disease.
1/2022	Therapeutic drug monitoring of biologics in inflammatory bowel disease: unmet needs and future perspectives.
12/2021	PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis.
12/2021	Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease.
11/2021	Anti-Drug Antibody Formation Against Biologic Agents in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.

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William J Sandborn Research Topics

Disease

238	Crohn Disease (Crohn's Disease) 11/2022 - 01/2002
201	Ulcerative Colitis 10/2022 - 04/2002
118	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2022 - 01/2002
51	Infections 11/2022 - 12/2002
31	Inflammation (Inflammations) 06/2022 - 05/2002
29	Necrosis 01/2022 - 02/2003
26	Neoplasms (Cancer) 01/2022 - 04/2002
25	Hemorrhage 01/2022 - 12/2005
14	Colitis 01/2022 - 04/2002
14	Body Weight (Weight, Body) 01/2021 - 11/2004
13	Fistula 01/2019 - 09/2002
12	Rheumatoid Arthritis 01/2022 - 05/2002
9	Ulcer 11/2022 - 04/2012
9	Pouchitis 01/2022 - 04/2002
9	Delayed Hypersensitivity (Hypersensitivity, Type IV) 05/2010 - 05/2002
8	Diarrhea 12/2019 - 11/2002
7	Proctitis 11/2022 - 05/2012
7	Abdominal Pain (Pain, Abdominal) 10/2022 - 08/2013
7	Skin Neoplasms (Skin Cancer) 01/2022 - 04/2014
7	Herpes Zoster 01/2022 - 10/2009
7	Obesity 01/2021 - 01/2017
7	Colorectal Neoplasms (Colorectal Cancer) 05/2017 - 01/2006
6	Pathologic Constriction (Stenosis) 01/2022 - 05/2004
6	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2022 - 05/2015
6	Tuberculosis (Tuberculoses) 01/2014 - 12/2002
5	Sepsis (Septicemia) 08/2022 - 04/2009
5	Opportunistic Infections (Opportunistic Infection) 01/2019 - 04/2008
5	Abscess 01/2019 - 01/2009
5	Disease Progression 01/2016 - 02/2006
5	Lymphoma (Lymphomas) 06/2013 - 01/2002
5	Demyelinating Diseases (Demyelinating Disease) 09/2011 - 12/2003
4	Injection Site Reaction 01/2022 - 02/2006
4	Hypersensitivity (Allergy) 01/2019 - 10/2004
4	Leukopenia 01/2018 - 07/2003
4	Multiple Sclerosis 01/2018 - 01/2004
4	Weight Loss (Weight Reduction) 01/2018 - 11/2002
4	Microscopic Colitis 02/2013 - 01/2006
3	Melanoma (Melanoma, Malignant) 01/2022 - 01/2019
3	Arthralgia (Joint Pain) 01/2022 - 02/2006
3	Psoriatic Arthritis 01/2022 - 01/2019

Drug/Important Bio-Agent (IBA)

75	Infliximab (Remicade)FDA Link 12/2021 - 05/2002
59	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 05/2002
49	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2022 - 08/2002
45	vedolizumabIBA 01/2022 - 01/2004
43	Pharmaceutical PreparationsIBA 11/2022 - 11/2002
42	Adalimumab (Humira)FDA Link 11/2022 - 02/2003
39	Monoclonal AntibodiesIBA 01/2022 - 05/2002
38	Biological ProductsIBA 11/2022 - 05/2002
32	Tumor Necrosis Factor InhibitorsIBA 01/2022 - 01/2004
30	Mesalamine (Mesalazine)FDA LinkGeneric 01/2022 - 01/2002
29	C-Reactive ProteinIBA 10/2022 - 12/2003
27	Biomarkers (Surrogate Marker)IBA 06/2022 - 07/2003
25	Certolizumab Pegol FDA Link 01/2022 - 02/2003
25	tofacitinibIBA 01/2022 - 08/2012
24	Azathioprine (Imuran)FDA LinkGeneric 07/2022 - 01/2002
21	Ustekinumab (CNTO 1275)FDA Link 11/2022 - 10/2008
20	Immunosuppressive Agents (Immunosuppressants)IBA 12/2021 - 12/2003
18	Leukocyte L1 Antigen Complex (Calgranulin)IBA 10/2022 - 11/2008
17	IntegrinsIBA 07/2022 - 11/2003
17	SteroidsIBA 01/2020 - 09/2002
17	Budesonide (Pulmicort)FDA LinkGeneric 12/2017 - 01/2002
15	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 08/2022 - 01/2002
15	Janus Kinase InhibitorsIBA 01/2022 - 08/2012
14	golimumab FDA Link 01/2021 - 01/2014
13	Immunologic Factors (Immunomodulators)IBA 01/2022 - 12/2008
13	AntibodiesIBA 11/2021 - 02/2003
11	Interleukin-12 (IL 12)IBA 01/2020 - 05/2002
10	CytokinesIBA 01/2022 - 05/2002
10	Interleukin-23 (Interleukin 23)IBA 01/2022 - 10/2008
8	Natalizumab (Tysabri)FDA Link 01/2018 - 05/2002
7	ozanimodIBA 01/2022 - 01/2016
7	Phenobarbital (Luminal)FDA Link 01/2022 - 05/2006
6	InterleukinsIBA 07/2022 - 03/2015
6	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 10/2007
6	risankizumabIBA 01/2022 - 01/2017
6	Methotrexate (Mexate)FDA LinkGeneric 01/2021 - 12/2002
5	ontamalimabIBA 01/2022 - 01/2017
5	AlbuminsIBA 01/2021 - 01/2013
5	Serum AlbuminIBA 01/2020 - 04/2012
5	LactoferrinIBA 01/2020 - 06/2003
5	Sulfasalazine (Azulfidine)FDA LinkGeneric 04/2010 - 01/2002
4	Janus Kinase 1IBA 01/2022 - 01/2020
4	etrolizumabIBA 01/2022 - 07/2014
4	upadacitinibIBA 01/2022 - 01/2020
4	Bile Acids and Salts (Bile Acids)IBA 01/2020 - 08/2006
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 05/2002
4	Prednisone (Sone)FDA LinkGeneric 12/2017 - 05/2006
4	Ciprofloxacin (Cipro)FDA LinkGeneric 11/2015 - 01/2009
4	recombinant human tumor necrosis factor-binding protein-1IBA 07/2006 - 05/2002
4	Etanercept (Enbrel)FDA Link 01/2005 - 05/2002
3	mirikizumabIBA 01/2022 - 01/2020
3	Opiate AlkaloidsIBA 01/2022 - 01/2021

Therapy/Procedure

205	Therapeutics 11/2022 - 01/2002
29	Biological Therapy 05/2022 - 05/2002
17	Colectomy 10/2021 - 04/2002
14	Remission Induction 01/2020 - 01/2002
9	Restorative Proctocolectomy 01/2022 - 09/2002
6	Aftercare (After-Treatment) 01/2022 - 10/2009
5	Drug Therapy (Chemotherapy) 01/2020 - 12/2005
4	Blood Component Removal (Apheresis) 08/2008 - 12/2005