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Pilar Sancho Selected Research

Dequalinium (Dequalinium Chloride)

7/2014Dequalinium induces cytotoxicity in human leukemia NB4 cells by downregulation of Raf/MEK/ERK and PI3K/Akt signaling pathways and potentiation of specific inhibitors of these pathways.
12/2011Dequalinium induces apoptosis in peripheral blood mononuclear cells isolated from human chronic lymphocytic leukemia.
10/2011Dequalinium induces human leukemia cell death by affecting the redox balance.
7/2007Dequalinium induces cell death in human leukemia cells by early mitochondrial alterations which enhance ROS production.
10/2005Effects of the antitumoural dequalinium on NB4 and K562 human leukemia cell lines. Mitochondrial implication in cell death.
9/2003In vivo biodistribution of erythrocytes and polyethyleneglycol-phosphatidylethanolamine micelles carrying the antitumour agent dequalinium.

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Pilar Sancho Research Topics

Disease

6Leukemia
07/2014 - 10/2005
4Neoplasms (Cancer)
06/2015 - 09/2003
2Acute Promyelocytic Leukemia
07/2014 - 10/2005
1Osteoporotic Fractures
01/2012
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
12/2011
1Carcinoma (Carcinomatosis)
10/2005
1Hemolysis
09/2002

Drug/Important Bio-Agent (IBA)

6Dequalinium (Dequalinium Chloride)IBA
07/2014 - 09/2003
2Phosphotransferases (Kinase)IBA
07/2014 - 03/2010
1Vinblastine (Vinblastine Sulfate)FDA Link
06/2015
1Dihydrotachysterol (AT 10)IBA
01/2012
1lonidamineIBA
12/2011
1arsenic trioxide (Trisenox)FDA Link
12/2011
1Methanol (Carbinol)IBA
03/2010
1MicellesIBA
09/2003
1phosphatidylethanolamineIBA
09/2003
1dioleoyl-N-(monomethoxypolyethylene glycol succinyl)phosphatidylethanolamineIBA
09/2003
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
09/2003
1Transferrin (beta 2 Transferrin)IBA
09/2002

Therapy/Procedure

1Drug Therapy (Chemotherapy)
10/2005