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Antonio Rossi Selected Research

Prolidase Deficiency

3/2015Lack of prolidase causes a bone phenotype both in human and in mouse.
1/2013Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue.
1/2012Partial Rescue of Biochemical Parameters After Hematopoietic Stem Cell Transplantation in a Patient with Prolidase Deficiency Due to Two Novel PEPD Mutations.
9/2011Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis.
12/2006Human recombinant prolidase from eukaryotic and prokaryotic sources. Expression, purification, characterization and long-term stability studies.
6/2005N-benzyloxycarbonyl-L-proline: an in vitro and in vivo inhibitor of prolidase.
9/2003Optimization of a capillary electrophoretic method to detect and quantify the Gly-Pro dipeptide in complex matrices from long term cultured prolidase deficiency fibroblasts.

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Antonio Rossi Research Topics

Disease

64Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/2015 - 03/2003
29Neoplasms (Cancer)
12/2015 - 07/2004
13Lung Neoplasms (Lung Cancer)
09/2015 - 03/2003
8Small Cell Lung Carcinoma (Small Cell Lung Cancer)
08/2013 - 06/2002
7Prolidase Deficiency
03/2015 - 09/2003
7Shock
05/2014 - 02/2008
6Infection
12/2014 - 06/2003
6Neoplasm Metastasis (Metastasis)
06/2011 - 03/2003
6Colorectal Neoplasms (Colorectal Cancer)
04/2011 - 01/2002
5Disease Progression
01/2014 - 06/2007
5Vomiting
08/2013 - 01/2002
4Osteogenesis Imperfecta (Lobstein Disease)
05/2014 - 06/2007
4Osteochondrodysplasias (Spondyloepiphyseal Dysplasia)
08/2012 - 07/2003
4Breast Neoplasms (Breast Cancer)
12/2008 - 03/2003
3Adenocarcinoma
06/2015 - 05/2010
3Diarrhea
08/2013 - 01/2002
3Nausea
08/2013 - 01/2002
3Dislocations
08/2012 - 06/2008
3Neutropenia
10/2009 - 01/2002
2Circulating Neoplastic Cells
01/2015 - 07/2009
2Developmental Bone Diseases (Bone Dysplasia)
05/2014 - 07/2012
2Inflammation
12/2013 - 01/2012
2Thrombocytopenia (Thrombopenia)
08/2013 - 03/2007
2Hypersensitivity (Allergy)
01/2013 - 01/2003
2Pain (Aches)
12/2012 - 06/2007
2Constipation
12/2012 - 06/2007
2Dysostoses
10/2010 - 06/2008
2Exanthema (Rash)
04/2010 - 10/2007
2Amyloidosis
02/2008 - 06/2006
2Fever (Fevers)
06/2007 - 08/2006
2Chronic Kidney Failure (Chronic Renal Failure)
01/2007 - 03/2005
2Mucositis
01/2003 - 01/2002
1Hypertelorism
03/2015
1Genu Valgum
03/2015
1Metabolic Bone Diseases (Osteopenia)
03/2015
1Microcephaly
03/2015
1Dermatomycoses (Dermatophytosis)
01/2015
1Human Influenza (Influenza)
12/2014
1Influenza in Birds (Avian Flu)
12/2014
1Multiple Myeloma
05/2014
1Hyperaldosteronism (Conn Syndrome)
05/2014
1Adenoma (Adenomas)
05/2014

Drug/Important Bio-Agent (IBA)

14Epidermal Growth Factor Receptor (EGF Receptor)IBA
11/2015 - 05/2004
13erlotinib (CP 358,774)FDA Link
01/2014 - 01/2007
12PlatinumIBA
10/2014 - 11/2005
10Cisplatin (Platino)FDA LinkGeneric
03/2014 - 01/2003
8bevacizumabFDA Link
01/2015 - 10/2007
8gemcitabineFDA Link
03/2014 - 03/2007
8gefitinib (Iressa)FDA Link
01/2014 - 05/2004
7pemetrexed (MTA)FDA Link
06/2015 - 03/2007
7Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2015 - 05/2004
7cetuximab (Erbitux)FDA Link
06/2014 - 08/2006
6proline dipeptidase (prolidase)IBA
03/2015 - 06/2005
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2013 - 10/2007
5Fluorouracil (Carac)FDA LinkGeneric
05/2003 - 01/2002
4CollagenIBA
05/2014 - 06/2006
4Proteins (Proteins, Gene)IBA
01/2013 - 06/2007
3Biological Markers (Surrogate Marker)IBA
05/2014 - 07/2013
3Phosphotransferases (Kinase)IBA
01/2013 - 02/2007
3Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2012 - 08/2006
3Adenocarcinoma of lungIBA
06/2011 - 05/2005
3Monoclonal AntibodiesIBA
11/2010 - 09/2008
3Diastrophic dysplasiaIBA
01/2006 - 07/2003
3vinorelbine (Navelbine)FDA LinkGeneric
03/2003 - 06/2002
3Leucovorin (Folinic Acid)FDA Link
03/2003 - 01/2002
2anaplastic lymphoma kinaseIBA
11/2015 - 03/2013
2EnzymesIBA
06/2015 - 09/2012
2DNA (Deoxyribonucleic Acid)IBA
01/2015 - 02/2008
2Collagen Type I (Type I Collagen)IBA
05/2014 - 07/2009
2Histone Deacetylase InhibitorsIBA
08/2013 - 10/2008
2ChondroitinIBA
08/2012 - 10/2010
2Carboplatin (JM8)FDA LinkGeneric
05/2012 - 06/2002
2Carbon MonoxideIBA
01/2012 - 12/2003
2VaccinesIBA
06/2011 - 09/2009
2carbohydrate sulfotransferases (keratan sulfotransferase)IBA
10/2010 - 06/2008
2Keratins (Keratin)IBA
02/2010 - 07/2009
2CytokinesIBA
10/2009 - 05/2007
2trastuzumab (Herceptin)FDA Link
12/2008 - 01/2004
2everolimusFDA Link
02/2008 - 11/2007
2sorafenib (BAY 43-9006)FDA Link
05/2007 - 02/2007
2irinotecan (Camptosar)FDA LinkGeneric
05/2003 - 01/2002
1Protein Kinases (Protein Kinase)IBA
09/2015
1NucleotidesIBA
06/2015
1Mutant Proteins (Protein, Mutant)IBA
03/2015
1Itraconazole (Sporanox)FDA LinkGeneric
01/2015
1micafungin (FK463)FDA Link
01/2015
1ProstaglandinsIBA
12/2014
1prostaglandin A1 (PGA1)IBA
12/2014
1cyclopentenoneIBA
12/2014
1bortezomib (Velcade)FDA Link
05/2014
1Proteasome Endopeptidase Complex (Proteasome)IBA
05/2014
1RNA (Ribonucleic Acid)IBA
05/2014
1arseniteIBA
05/2014
1Staphylococcal Protein A (A, Protein)IBA
05/2014
1CationsIBA
05/2014

Therapy/Procedure

40Drug Therapy (Chemotherapy)
12/2014 - 01/2003
4Adjuvant Chemotherapy
07/2011 - 01/2007
3Radiotherapy
09/2011 - 05/2005
1Polypharmacy
12/2015
1Immunotherapy
12/2014