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Stefan Rose-John Selected Research

Interleukin-6 (Interleukin 6)

07/2008	The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6.
02/2008	A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population.
02/2008	Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.
10/2007	Conservation of IL-6 trans-signaling mechanisms controlling L-selectin adhesion by fever-range thermal stress.
07/2007	Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo.
12/2006	Interleukin-6 trans-signaling in inflammatory bowel disease.
12/2006	Fever-range thermal stress promotes lymphocyte trafficking across high endothelial venules via an interleukin 6 trans-signaling mechanism.
08/2006	Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer.
09/2005	Viral IL-6 blocks neutrophil infiltration during acute inflammation.
10/2004	TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.
11/2003	Role of interleukin-6 for LV remodeling and survival after experimental myocardial infarction.
09/2003	Soluble IL-6 receptor governs IL-6 activity in experimental arthritis: blockade of arthritis severity by soluble glycoprotein 130.
08/2003	Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation.
05/2002	Human herpesvirus 8-derived viral IL-6 induces PTX3 expression in Kaposi's sarcoma cells.

Articles by Research Topic

Disease

5	Inflammation 02/2008 - 08/2003
3	Neoplasms (Cancer) 01/2007 - 10/2004
2	Colitis 09/2008 - 07/2008
2	Myocardial Infarction 02/2008 - 11/2003
2	Fever (Fevers) 10/2007 - 12/2006
1	Tissue Adhesions 10/2007
1	Hypertension (High Blood Pressure) 07/2007
1	Hypertrophy 07/2007
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2006
1	Insulin Resistance 05/2006
1	Obesity 05/2006
1	Uveitis 10/2004
1	Colonic Neoplasms (Colon Cancer) 10/2004
1	Arthritis (Polyarthritis) 09/2003
1	Experimental Arthritis 09/2003
1	Kaposi Sarcoma (Kaposi's Sarcoma) 05/2002

Drug/Important Bio-Agent (IBA)

14	Interleukin-6 (Interleukin 6)IBA 07/2008 - 05/2002
2	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 10/2004 - 09/2003
1	NFATC Transcription FactorsIBA 09/2008
1	Transcription Factors (Transcription Factor)IBA 07/2008
1	Cytokine Receptor gp130IBA 02/2008
1	L-SelectinIBA 10/2007
1	Angiotensin IIIBA 07/2007
1	CytokinesIBA 01/2007
1	Ciliary Neurotrophic Factor (CNTF)IBA 05/2006
1	Transforming Growth Factor beta (TGF-beta)IBA 10/2004
1	Glycoproteins (Glycoprotein)IBA 09/2003