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Claus G Roehrborn Selected Research

Prostatic Hyperplasia (Benign Prostatic Hyperplasia)

9/2015Efficacy and safety of a fixed-dose combination of dutasteride and tamsulosin treatment (Duodart(®) ) compared with watchful waiting with initiation of tamsulosin therapy if symptoms do not improve, both provided with lifestyle advice, in the management of treatment-naïve men with moderately symptomatic benign prostatic hyperplasia: 2-year CONDUCT study results.
6/2015Treatment satisfaction and clinically meaningful symptom improvement in men with lower urinary tract symptoms and prostatic enlargement secondary to benign prostatic hyperplasia: Secondary results from a 6-month, randomized, double-blind study comparing finasteride plus tadalafil with finasteride plus placebo.
1/2015Sexual function in men with lower urinary tract symptoms and prostatic enlargement secondary to benign prostatic hyperplasia: results of a 6-month, randomized, double-blind, placebo-controlled study of tadalafil coadministered with finasteride.
10/2014Impact of dutasteride on nocturia in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH): a pooled analysis of three phase III studies.
10/2014Nocturia improvement in the combination of Avodart(®) and tamsulosin (CombAT) study.
7/2014A multicenter, randomized, double-blind, placebo controlled study of onabotulinumtoxinA 200 U to treat lower urinary tract symptoms in men with benign prostatic hyperplasia.
5/2014Prostate cancer detection using combined auto-fluorescence and light reflectance spectroscopy: ex vivo study of human prostates.
4/2014Influence of baseline variables on changes in International Prostate Symptom Score after combined therapy with dutasteride plus tamsulosin or either monotherapy in patients with benign prostatic hyperplasia and lower urinary tract symptoms: 4-year results of the CombAT study.
4/2014Effects of tadalafil once daily on maximum urinary flow rate in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
4/2014Actual medical management of lower urinary tract symptoms related to benign prostatic hyperplasia: temporal trends of prescription and hospitalization rates over 5 years in a large population of Italian men.
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Claus G Roehrborn Research Topics

Disease

74Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
09/2015 - 06/2002
54Prostatic Neoplasms (Prostate Cancer)
06/2014 - 01/2002
23Neoplasms (Cancer)
02/2015 - 01/2002
17Neoplasm Metastasis (Metastasis)
10/2014 - 03/2004
16Urinary Retention
11/2012 - 06/2002
13Erectile Dysfunction
03/2014 - 11/2003
10Disease Progression
06/2008 - 01/2003
8Overactive Urinary Bladder (Overactive Bladder)
08/2012 - 05/2006
6Nocturia
10/2014 - 08/2006
6Adenocarcinoma
11/2008 - 06/2003
5Urinary Incontinence
02/2009 - 12/2003
5Urinary Bladder Neoplasms (Bladder Cancer)
09/2008 - 01/2002
3Pain (Aches)
04/2013 - 09/2007
3Inflammation
08/2012 - 09/2007
3Shock
04/2007 - 04/2002
3Transitional Cell Carcinoma
09/2006 - 01/2002
2Infection
02/2013 - 11/2003
2Constipation
06/2012 - 05/2006
2Prostatitis
09/2011 - 09/2007
2Carcinoma (Carcinomatosis)
02/2008 - 02/2007
2Hypertension (High Blood Pressure)
10/2007 - 11/2003
2Hypotension (Low Blood Pressure)
04/2007 - 03/2004
2Dizziness (Lightheadedness)
05/2006 - 11/2003
1Hypogonadism (Hypergonadotropic Hypogonadism)
03/2013
1Bacteremia
02/2013
1Fatigue
10/2012
1Dysuria
06/2012
1Atherosclerosis
10/2011
1Ischemia
03/2011
1Obesity
10/2010
1Heart Failure
01/2010
1Parkinsonian Disorders (Parkinsonism)
10/2009
1Urge Urinary Incontinence (Urge Incontinence)
11/2008
1Morbid Obesity
09/2008
1Calculi (Calculus)
09/2008
1Cicatrix (Scar)
09/2008

Drug/Important Bio-Agent (IBA)

36Prostate-Specific Antigen (Semenogelase)IBA
02/2015 - 01/2002
25dutasteride (Avodart)FDA Link
09/2015 - 09/2002
21Finasteride (Propecia)FDA LinkGeneric
06/2015 - 06/2002
15tamsulosin (Flomax)FDA LinkGeneric
09/2015 - 11/2006
13tadalafil (Cialis)FDA Link
06/2015 - 04/2007
8Testosterone (Sustanon)FDA Link
08/2013 - 11/2003
6tolterodine (Detrol)FDA Link
02/2009 - 05/2006
5Doxazosin (Cardura)FDA LinkGeneric
09/2008 - 12/2003
5Biological Markers (Surrogate Marker)IBA
06/2008 - 11/2005
5alfuzosin (UroXatral)FDA Link
01/2008 - 11/2003
4Phosphodiesterase 5 InhibitorsIBA
05/2012 - 01/2008
4Interleukin-6 (Interleukin 6)IBA
11/2011 - 04/2008
3Muscarinic AntagonistsIBA
06/2012 - 11/2006
3Plasminogen Activators (Plasminogen Activator)IBA
06/2009 - 10/2007
3Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
06/2009 - 02/2007
3PlasminogenIBA
06/2009 - 02/2007
3nuclear matrix protein 22IBA
02/2008 - 05/2005
2onabotulinumtoxinA (Botox)FDA Link
07/2014 - 09/2011
2HormonesIBA
06/2014 - 12/2006
2Androgen Receptors (Androgen Receptor)IBA
08/2013 - 01/2008
25'-Guanylic Acid (GMP)IBA
10/2011 - 03/2011
2Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2011 - 03/2011
2Type 5 Cyclic Nucleotide PhosphodiesterasesIBA
02/2010 - 01/2004
2Urokinase Plasminogen Activator ReceptorsIBA
06/2009 - 02/2007
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2009 - 06/2008
2Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
06/2009 - 06/2008
2Adrenergic Antagonists (Antiadrenergic Agents)IBA
02/2009 - 12/2003
2DioxinsIBA
11/2006 - 07/2006
2Dihydrotestosterone (Androstanolone)IBA
04/2006 - 09/2002
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
06/2014
1OxidoreductasesIBA
04/2014
1proaerolysinIBA
04/2013
1PRX302IBA
04/2013
1Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)FDA LinkGeneric
02/2013
1Gentamicins (Gentamicin)FDA LinkGeneric
02/2013
1Ciprofloxacin (Cipro)FDA LinkGeneric
02/2013
1C-Reactive ProteinIBA
08/2012
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
08/2012
1ORALIT (ORS)IBA
08/2012
1fesoterodineFDA Link
06/2012
1Cadherins (E-Cadherin)IBA
11/2011
1Cytokine Receptor gp130IBA
11/2011
1rho-Associated KinasesIBA
10/2011
1Phosphotransferases (Kinase)IBA
03/2011
1KMD 3213FDA Link
01/2011
1Parasympatholytics (Antispasmodics)IBA
10/2009
1Plasminogen Activator Inhibitor 1IBA
05/2009
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
11/2008

Therapy/Procedure

31Prostatectomy (Retropubic Prostatectomy)
10/2014 - 06/2003
8Lymph Node Excision (Lymph Node Dissection)
11/2008 - 02/2007
5Aftercare (After-Treatment)
01/2012 - 01/2002
5Chemoprevention
03/2008 - 03/2004
3Catheters
05/2011 - 01/2005
3Radiotherapy
09/2008 - 06/2003
2Transurethral Resection of Prostate (TURP)
04/2011 - 01/2008
2Lasers (Laser)
04/2011 - 01/2006
2Drug Therapy (Chemotherapy)
09/2008 - 01/2005
2Lithotripsy (Extracorporeal Shockwave Lithotripsy)
11/2004 - 04/2002
1Drug Prescriptions
04/2014
1Castration
08/2013
1Phytotherapy (Herbal Therapy)
03/2013
1Antibiotic Prophylaxis
02/2013
1Adjuvant Radiotherapy
12/2008
1Therapeutics
12/2008