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Olivier Rascol Selected Research

Parkinson Disease (Parkinson's Disease)

12/2015Preladenant as an Adjunctive Therapy With Levodopa in Parkinson Disease: Two Randomized Clinical Trials and Lessons Learned.
12/2015Prolonged-release oxycodone-naloxone for treatment of severe pain in patients with Parkinson's disease (PANDA): a double-blind, randomised, placebo-controlled trial.
10/2015Impact of Current Antipsychotic Medications on Comparative Mortality and Adverse Events in People With Parkinson Disease Psychosis.
9/2015New treatments for levodopa-induced motor complications.
5/2015Polymorphism of the dopamine transporter type 1 gene modifies the treatment response in Parkinson's disease.
9/2014Parkinson disease: Can a new trial end controversy over when to use levodopa?
9/2014Use of metabotropic glutamate 5-receptor antagonists for treatment of levodopa-induced dyskinesias.
7/2014The mGluR5 negative allosteric modulator dipraglurant reduces dyskinesia in the MPTP macaque model.
3/2014Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial.
3/2014Risk of heart failure following treatment with dopamine agonists in Parkinson's disease patients.
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Olivier Rascol Research Topics

Disease

78Parkinson Disease (Parkinson's Disease)
12/2015 - 01/2003
28Dyskinesias (Dyskinesia)
10/2015 - 01/2003
7Pain (Aches)
12/2015 - 01/2003
7Orthostatic Hypotension (Postural Hypotension)
10/2015 - 07/2011
7Parkinsonian Disorders (Parkinsonism)
04/2013 - 05/2005
6Multiple System Atrophy
02/2015 - 08/2003
6Nausea
08/2013 - 04/2010
5Dementia (Dementias)
07/2014 - 10/2005
4Constipation
12/2015 - 11/2010
4Hallucinations (Hallucination)
10/2015 - 12/2009
4Disease Progression
07/2014 - 05/2005
4Impulse Control Disorders (Kleptomania)
03/2014 - 09/2010
4Fatigue
01/2014 - 11/2010
4Drug Toxicity (Drug Safety)
07/2011 - 05/2008
3Dizziness (Lightheadedness)
02/2015 - 04/2010
3Neuralgia (Stump Neuralgia)
05/2013 - 06/2012
3Sialorrhea
03/2013 - 01/2011
3Hypokinesia (Bradykinesia)
07/2012 - 10/2005
3Primary Dysautonomias (Dysautonomia)
01/2006 - 08/2003
2Movement Disorders (Movement Disorder)
03/2013 - 02/2007
2Erectile Dysfunction
03/2013 - 10/2011
2Restless Legs Syndrome (Restless Legs)
02/2013 - 12/2012
2Dystonia (Limb Dystonia)
06/2012 - 08/2003
2Sleep Initiation and Maintenance Disorders (Insomnia)
10/2011 - 10/2005
2Gambling (Pathological Gambling)
10/2011 - 01/2006
2Vomiting
07/2011 - 09/2010
2Atrophy
11/2010 - 08/2009
2Tremor (Tremors)
01/2009 - 10/2005
2Stroke (Strokes)
11/2006 - 01/2002
2Heart Valve Diseases (Valvular Heart Disease)
08/2006 - 06/2004
1Infection
10/2015
1Edema
10/2015
1Urinary Tract Infections (Urinary Tract Infection)
02/2015
1Neurodegenerative Diseases (Neurodegenerative Disease)
07/2014
1Fibrosis (Cirrhosis)
03/2014
1Heart Failure
03/2014
1Body Weight (Weight, Body)
07/2013
1Urinary Incontinence
03/2013

Drug/Important Bio-Agent (IBA)

48Levodopa (L Dopa)FDA LinkGeneric
12/2015 - 01/2003
16pramipexol (pramipexole)FDA LinkGeneric
03/2014 - 06/2007
13Dopamine Agonists (Dopamine Agonist)IBA
03/2014 - 07/2003
9rasagiline (Azilect)FDA Link
02/2015 - 05/2005
7Dopamine (Intropin)FDA LinkGeneric
03/2014 - 07/2003
6Amantadine (Aman)FDA LinkGeneric
09/2015 - 05/2011
6Pergolide (Permax)FDA Link
10/2011 - 05/2005
6ropinirole (Requip)FDA LinkGeneric
10/2011 - 07/2003
5entacapone (Comtan)FDA Link
07/2013 - 09/2004
4Antipsychotic Agents (Antipsychotics)IBA
10/2015 - 02/2007
4Methylphenidate (Ritalin)FDA LinkGeneric
05/2015 - 11/2006
4Carbidopa (Lodosyn)FDA LinkGeneric
07/2013 - 07/2010
4N 0437FDA Link
02/2013 - 06/2007
3cabergolineFDA LinkGeneric
03/2014 - 12/2009
3Botulinum Toxins (Botulinum Toxin)IBA
03/2013 - 10/2011
3Antidepressive Agents (Antidepressants)IBA
12/2012 - 06/2010
3Dopamine Agents (Dopaminergic Agents)IBA
07/2012 - 01/2006
3perampanelIBA
02/2012 - 05/2010
3Piribedil (Trivastal)IBA
02/2010 - 04/2003
3sarizotanIBA
04/2008 - 03/2004
2Naloxone (Narcan)FDA LinkGeneric
12/2015 - 06/2012
2Oxycodone (Oxycontin)FDA LinkGeneric
12/2015 - 06/2012
2Glutamic Acid (Glutamate)FDA Link
09/2014 - 05/2011
2Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
09/2014 - 07/2014
2amsonic acid (DAS)IBA
03/2014 - 09/2010
2Pain-FreeIBA
05/2013 - 11/2012
2sildenafil (Viagra)FDA Link
03/2013 - 10/2011
2Glycopyrrolate (Glycopyrronium Bromide)FDA LinkGeneric
03/2013 - 10/2011
2Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
03/2013 - 10/2011
2hydroxide ionIBA
03/2013 - 06/2012
2Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
07/2012 - 10/2011
2ApomorphineIBA
06/2012 - 09/2004
2Clozapine (Clozaril)FDA LinkGeneric
10/2011 - 10/2011
2SLV-308IBA
07/2011 - 04/2010
2Selegiline (E250)FDA LinkGeneric
05/2011 - 05/2005
2Monoamine Oxidase (MAO)IBA
05/2011 - 10/2005
2IronIBA
11/2010 - 08/2009
2ErgolinesIBA
02/2010 - 08/2006
23-Iodobenzylguanidine (Iobenguane)IBA
01/2009 - 08/2003
2fluorodopa F 18IBA
07/2003 - 05/2003
1AdenosineFDA LinkGeneric
12/2015
1preladenantIBA
12/2015
1insulin receptor-related receptor (IRR)IBA
10/2015
1DiureticsIBA
10/2015
1N-Methylaspartate (NMDA)IBA
09/2015
1Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
05/2015
1alpha-SynucleinIBA
07/2014
1Biological Markers (Surrogate Marker)IBA
07/2014
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
07/2014
1metabotropic glutamate receptor 5IBA
07/2014
1Dopamine Receptors (Dopamine Receptor)IBA
03/2014
1pamidronate (APD)FDA LinkGeneric
01/2014
1StalevoIBA
07/2013
1Carbon MonoxideIBA
04/2013
1levodopa drug combination carbidopa (Nakom)FDA LinkGeneric
04/2013
1Phosphotransferases (Kinase)IBA
04/2013
1Simvastatin (Zocor)FDA LinkGeneric
04/2013
1lubiprostoneFDA Link
03/2013
1TropicamideFDA LinkGeneric
03/2013

Therapy/Procedure

6Activities of Daily Living (ADL)
10/2015 - 05/2008
4Deep Brain Stimulation
11/2013 - 02/2007
2Sympathectomy (Sympathectomies)
01/2009 - 08/2003