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Sonia A Perez Selected Research

invariant chain (Ii-Key)

9/2015A pilot study in prostate cancer patients treated with the AE37 Ii-key-HER-2/neu polypeptide vaccine suggests that HLA-A*24 and HLA-DRB1*11 alleles may be prognostic and predictive biomarkers for clinical benefit.
11/2014AE37 peptide vaccination in prostate cancer: identification of biomarkers in the context of prognosis and prediction.
7/2010Results from a phase I clinical study of the novel Ii-Key/HER-2/neu(776-790) hybrid peptide vaccine in patients with prostate cancer.
5/2007Ii-Key/HER-2/neu(776-790) hybrid peptides induce more effective immunological responses over the native peptide in lymphocyte cultures from patients with HER-2/neu+ tumors.

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Sonia A Perez Research Topics

Disease

26Neoplasms (Cancer)
04/2015 - 01/2002
7Prostatic Neoplasms (Prostate Cancer)
09/2015 - 12/2003
6Breast Neoplasms (Breast Cancer)
01/2014 - 05/2007
2Hypersensitivity (Allergy)
09/2015 - 11/2014
2Melanoma (Melanoma, Malignant)
01/2014 - 01/2002
2Adenocarcinoma
12/2010 - 01/2002
2Carcinoma (Carcinomatosis)
03/2010 - 01/2002
1Malaria
01/2014
1Colorectal Neoplasms (Colorectal Cancer)
04/2013
1Azoospermia
09/2011
1Neoplasm Metastasis (Metastasis)
03/2011
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2010
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2010
1Disease Progression
05/2007
1Anterior Wall Myocardial Infarction
07/2005
1Cicatrix (Scar)
07/2005

Drug/Important Bio-Agent (IBA)

9VaccinesIBA
04/2015 - 01/2002
6AntigensIBA
04/2015 - 09/2005
5Biological Markers (Surrogate Marker)IBA
09/2015 - 04/2013
4invariant chain (Ii-Key)IBA
09/2015 - 05/2007
4AE37 vaccineIBA
11/2014 - 07/2010
4PeptidesIBA
05/2010 - 12/2003
4EpitopesIBA
05/2006 - 01/2002
3Cancer VaccinesIBA
04/2015 - 01/2014
3trastuzumab (Herceptin)FDA Link
01/2014 - 05/2007
2Interferon-gamma (Interferon, gamma)IBA
11/2014 - 05/2003
2Messenger RNA (mRNA)IBA
05/2013 - 09/2011
2Interleukin-15 (Interleukin 15)IBA
03/2011 - 03/2005
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
07/2010 - 05/2003
2Monoclonal AntibodiesIBA
03/2009 - 01/2009
2Interleukin-18 (Interleukin 18)IBA
03/2005 - 05/2003
2Interleukin-12 (IL 12)IBA
03/2005 - 05/2003
1InterferonsIBA
09/2015
1HLA-DRB1 antigen (HLA DRB1)IBA
09/2015
1HLA-A Antigens (HLA-A)IBA
09/2015
1Prostate-Specific Antigen (Semenogelase)IBA
04/2015
1Transforming Growth Factor beta (TGF-beta)IBA
11/2014
1Carbon MonoxideIBA
01/2014
1quinolineIBA
01/2014
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
01/2014
1Chloroquine (Aralen)FDA LinkGeneric
01/2014
1AntibodiesIBA
01/2014
1Epidermal Growth Factor (EGF)IBA
05/2013
1Calcibiotic Root Canal SealerIBA
04/2013
1Carrier Proteins (Binding Protein)IBA
09/2011
1Transcription Factors (Transcription Factor)IBA
09/2011
1Insulin (Novolin)FDA Link
09/2011
1Aligeron (AS 2)IBA
09/2011
1denileukin diftitox (Ontak)FDA Link
03/2011
1tranilast (N 5')IBA
12/2010
1HLA-A*0201 antigenIBA
05/2010
1Subunit VaccinesIBA
05/2010
1CytokinesIBA
01/2009
1LigandsIBA
05/2006
1Glycoproteins (Glycoprotein)IBA
01/2006
1Insulin-Like Growth Factor II (Somatomedin A)IBA
05/2005
1MonokinesIBA
03/2005
1Amino AcidsFDA Link
12/2003
1IgE Receptors (Fc epsilon RI)IBA
08/2003
1Interleukin-10 (Interleukin 10)IBA
05/2003
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2003
1HER-2-derived peptide 884-899IBA
01/2002
1HLA-DR4 Antigen (HLA DR4 Antigen)IBA
01/2002
1HLA-DR Antigens (HLA-DR)IBA
01/2002

Therapy/Procedure

13Immunotherapy
04/2015 - 03/2005
4Drug Therapy (Chemotherapy)
01/2014 - 05/2007
1Microspheres (Microsphere)
09/2005
1Transplantation (Transplant Recipients)
07/2005
1Injections
03/2005