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Ralf Paschke Selected Research

Thyroid Nodule (Nodule, Thyroid)

10/2006Similar prevalence of somatic TSH receptor and Gsalpha mutations in toxic thyroid nodules in geographical regions with different iodine supply in Turkey.
03/2006Comparison of differential gene expression of hot and cold thyroid nodules with primary epithelial cell culture models by investigation of co-regulated gene sets.
04/2005Two novel mutations in the sixth transmembrane segment of the thyrotropin receptor gene causing hyperfunctioning thyroid nodules.
11/2004Expression of regulators of g protein signaling mRNA is differentially regulated in hot and cold thyroid nodules.
07/2004Increased expression of G-protein-coupled receptor kinases 3 and 4 in hyperfunctioning thyroid nodules.
02/2004Lack of correlation for sodium iodide symporter mRNA and protein expression and analysis of sodium iodide symporter promoter methylation in benign cold thyroid nodules.
01/2004Gene expression analysis reveals evidence for inactivation of the TGF-beta signaling cascade in autonomously functioning thyroid nodules.
07/2002Expression of G(alpha)(s) proteins and TSH receptor signalling in hyperfunctioning thyroid nodules with TSH receptor mutations.

Articles by Research Topic

Disease

8Thyroid Nodule (Nodule, Thyroid)
10/2006 - 07/2002
3Pituitary Neoplasms (Pituitary Adenoma)
10/2008 - 04/2005
2Thyroid Neoplasms (Thyroid Cancer)
10/2006 - 11/2002
1Sarcoidosis (Schaumann Disease)
11/2007
1Hypercalcemia (Milk Alkali Syndrome)
11/2007
1DNA Damage
10/2007
1Neoplasms (Cancer)
10/2007
1Thyroid Hormone Resistance Syndrome (Thyroid Hormone Resistance)
06/2007
1Goiter
12/2006
1Hypothyroidism
10/2006
1Hyperthyroidism
09/2005
1Cardiovascular Diseases (Cardiovascular Disease)
11/2004
1Obesity
11/2004
1Neuroendocrine Tumors (Neuroendocrine Tumor)
08/2004
1Thyroid Crisis (Thyrotoxic Crisis)
10/2003

Drug/Important Bio-Agent (IBA)

4Thyrotropin Receptors (Thyrotropin Receptor)IBA
10/2006 - 07/2002
3Messenger RNA (mRNA)IBA
11/2004 - 11/2002
2aryl hydrocarbon receptor-interacting proteinIBA
10/2008 - 03/2007
2IodineIBA
12/2006 - 10/2006
1Vitamin DFDA LinkGeneric
11/2007
1Hydrogen Peroxide (Hydroperoxide)IBA
10/2007
1Thyroid Hormone Receptors beta (TR beta)IBA
06/2007
1SeleniumIBA
12/2006
1Thyroxine (Levothyroxine)FDA LinkGeneric
10/2006
1Carbon MonoxideIBA
03/2006
1ProlactinIBA
04/2005
1Growth Hormone (Somatotropin)IBA
04/2005
1AdiponectinIBA
11/2004
1GTP-Binding Proteins (G-Protein)IBA
11/2004
1Adrenocorticotropic Hormone (ACTH)FDA Link
08/2004
1G-Protein-Coupled Receptor KinasesIBA
07/2004
1sodium-iodide symporter (sodium iodide symporter)IBA
02/2004
1Transforming Growth Factor beta (TGF-beta)IBA
01/2004
1ThyroglobulinFDA Link
11/2002
1Proteins (Proteins, Gene)IBA
07/2002

Therapy/Procedure

1Ambulatory Care (Outpatient Care)
04/2005
1Thyroidectomy
10/2003