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Kyoung-Chan Park Selected Research

Hypopigmentation (Hypomelanosis)

8/2015Baicalin-induced Akt activation decreases melanogenesis through downregulation of microphthalmia-associated transcription factor and tyrosinase.
6/2014KHG26792 Inhibits Melanin Synthesis in Mel-Ab Cells and a Skin Equivalent Model.
5/2014A derivative of imidazobenzimidazole, ML106, inhibits melanin synthesis via p38 MAPK activation.
8/2012PP2A and DUSP6 are involved in sphingosylphosphorylcholine-induced hypopigmentation.
1/2011Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects.
5/2010Hypopigmentary action of dihydropyranocoumarin D2, a decursin derivative, as a MITF-degrading agent.
4/2006Sphingosylphosphorylcholine-induced ERK activation inhibits melanin synthesis in human melanocytes.
8/2005Heat treatment decreases melanin synthesis via protein phosphatase 2A inactivation.

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Kyoung-Chan Park Research Topics

Disease

10Melanoma (Melanoma, Malignant)
02/2014 - 01/2004
8Hypopigmentation (Hypomelanosis)
08/2015 - 08/2005
4Erythema
07/2012 - 07/2010
4Neoplasms (Cancer)
09/2009 - 01/2004
3Melanosis (Freckles)
07/2010 - 02/2010
2Skin Diseases
08/2015 - 03/2014
2Glioma (Gliomas)
08/2014 - 09/2012
2Vitiligo
03/2014 - 11/2005
2Inflammation
12/2012 - 04/2004
2Acne Vulgaris
02/2012 - 03/2011
2Atopic Dermatitis (Atopic Eczema)
08/2010 - 01/2010
1Hyperpigmentation
08/2015
1Neoplasm Metastasis (Metastasis)
12/2012
1Paronychia
12/2012
1Alopecia (Baldness)
01/2012
1Cicatrix (Scar)
04/2011
1Liver Neoplasms (Liver Cancer)
09/2009
1Psoriasis (Pustulosis Palmaris et Plantaris)
08/2009
1Parkinson Disease (Parkinson's Disease)
08/2007
1Neurodegenerative Diseases (Neurodegenerative Disease)
08/2007
1Experimental Melanoma
01/2007
1Brain Infarction
08/2004
1Ischemia
08/2004

Drug/Important Bio-Agent (IBA)

8indoleacetic acid (indole acetic acid)IBA
02/2012 - 01/2004
6Horseradish PeroxidaseIBA
09/2009 - 01/2004
5PD 98059IBA
06/2014 - 08/2005
5Melanins (Melanin)IBA
02/2014 - 03/2004
3Free RadicalsIBA
12/2006 - 01/2004
2Phosphotransferases (Kinase)IBA
08/2015 - 06/2014
2Leucine (L-Leucine)FDA Link
08/2014 - 09/2012
2alpha-MSHIBA
03/2013 - 01/2007
2sphingosine phosphorylcholineIBA
08/2012 - 01/2011
21-phenyl-3,3-dimethyltriazene (PDT)IBA
02/2012 - 03/2011
24-n-butylresorcinolIBA
04/2010 - 02/2010
2Monophenol Monooxygenase (Tyrosinase)IBA
04/2010 - 01/2007
1AMP-Activated Protein KinasesIBA
08/2015
1baicalinIBA
08/2015
1glycogen synthase kinase 3 betaIBA
05/2014
1beta CateninIBA
05/2014
1thermozymocidin (myriocin)IBA
03/2014
1ethyl 4-methoxycinnamateIBA
02/2014
1HormonesIBA
02/2014
1Melanocyte-Stimulating Hormones (MSH)IBA
02/2014
1Adenocarcinoma of lungIBA
12/2012
1gefitinib (Iressa)FDA Link
12/2012
1OligosaccharidesIBA
12/2012
1Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
08/2012
1Aminolevulinic Acid (Levulan)FDA Link
02/2012
1Methyl Green (Green, Light)IBA
02/2012
1Minoxidil (Rogaine)FDA LinkGeneric
01/2012
1indole-3-carbinolIBA
12/2011
1Glycogen Synthase KinasesIBA
08/2011
12-aminothiazoleIBA
08/2011
1omalizumab (Xolair)FDA Link
08/2010
1Chloroquine (Aralen)FDA LinkGeneric
05/2010
1benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA
05/2010
1Proteasome Endopeptidase Complex (Proteasome)IBA
05/2010
1Liposomes (Liposome)IBA
04/2010
1N 30IBA
01/2010
1Caspase 3 (Caspase-3)IBA
09/2009
1Protein Isoforms (Isoforms)IBA
08/2009
1Dopamine (Intropin)FDA LinkGeneric
08/2007
1Neurotransmitter Agents (Neurotransmitter)IBA
08/2007
12-imino-1,3-thiazolineIBA
01/2007
1KHG22394IBA
01/2007
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
08/2006
1AntioxidantsIBA
11/2005
1QuercetinIBA
11/2005
1Folic Acid (Vitamin M)FDA LinkGeneric
11/2005
1Carbon MonoxideIBA
11/2005
1U 0126 (UO 126)IBA
08/2005
1Superoxide DismutaseIBA
08/2004
1Glutathione PeroxidaseIBA
08/2004
1EnzymesIBA
08/2004
12,2'-azobis(2-amidinopropane) (ABAP)IBA
04/2004
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
04/2004
1kojic acidIBA
03/2004
1beta-thujaplicinIBA
03/2004

Therapy/Procedure

3Photochemotherapy (Photodynamic Therapy)
02/2012 - 09/2009
1East Asian Traditional Medicine (Oriental Medicine)
08/2015
1Excimer Lasers
07/2012
1Aftercare (After-Treatment)
10/2011
1Laser Therapy (Surgery, Laser)
04/2011
1Gas Lasers
04/2011
1Lasers (Laser)
07/2010
1Solid-State Lasers
07/2010
1Artificial Skin
08/2009