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Kristen Otto Selected Research

MAP Kinase Kinase 4

2/2012MKK4 suppresses metastatic colonization by multiple highly metastatic prostate cancer cell lines through a transient impairment in cell cycle progression.
4/2008c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.
3/2008Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines.

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Kristen Otto Research Topics

Disease

4Prostatic Neoplasms (Prostate Cancer)
04/2014 - 03/2008
2Neoplasms (Cancer)
04/2014 - 04/2008
2Neoplasm Metastasis (Metastasis)
02/2012 - 04/2008
1Ovarian Neoplasms (Ovarian Cancer)
04/2008
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2008
1Pathologic Constriction (Stenosis)
01/2008
1Esophageal Stenosis (Esophageal Stricture)
01/2008
1Head and Neck Neoplasms (Head and Neck Cancer)
01/2008

Drug/Important Bio-Agent (IBA)

3MAP Kinase Kinase 4IBA
02/2012 - 03/2008
3Phosphotransferases (Kinase)IBA
01/2009 - 03/2008
2PlatinumIBA
03/2008 - 01/2008
1Androgen Receptors (Androgen Receptor)IBA
04/2014
1MDV 3100IBA
04/2014
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
04/2014
1PaxillinIBA
01/2009
1Protein Kinases (Protein Kinase)IBA
04/2008
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
04/2008
1taxaneIBA
01/2008

Therapy/Procedure

2Heterologous Transplantation (Xenotransplantation)
04/2014 - 04/2008
2Drug Therapy (Chemotherapy)
03/2008 - 01/2008
1Radiotherapy
01/2008
1Combined Modality Therapy
01/2008