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Ian M Orme Selected Research
Granuloma
11/2007
XCL1 (lymphotactin) chemokine produced by activated CD8 T cells during the chronic stage of infection with Mycobacterium tuberculosis negatively affects production of IFN-gamma by CD4 T cells and participates in granuloma stability.
11/2006
Role for matrix metalloproteinase 9 in granuloma formation during pulmonary Mycobacterium tuberculosis infection.
09/2005
Foamy macrophages within lung granulomas of mice infected with Mycobacterium tuberculosis express molecules characteristic of dendritic cells and antiapoptotic markers of the TNF receptor-associated factor family.
Articles by Research Topic
Disease
9
Tuberculosis
01/2008 - 02/2003
6
Infection
04/2008 - 02/2002
3
Granuloma
11/2007 - 09/2005
2
Necrosis
10/2006 - 04/2003
1
Pneumonia (Pneumonitis)
08/2005
1
Cough
03/2004
1
Pulmonary Tuberculosis
12/2002
1
Leprosy (Hansen's Disease)
02/2002
Drug/Important Bio-Agent (IBA)
3
Interferon-gamma (Interferon, gamma)
IBA
10/2006 - 02/2002
3
DNA (Deoxyribonucleic Acid)
IBA
08/2005 - 04/2003
2
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
IBA
04/2008 - 06/2005
2
Vaccines
IBA
01/2006 - 01/2006
2
Antigens
IBA
06/2005 - 02/2002
1
Macrophage Colony-Stimulating Factor
IBA
04/2008
1
Iron-Binding Proteins
IBA
01/2008
1
Iron
IBA
01/2008
1
lymphotactin
IBA
11/2007
1
1- (6- bromo- 2- methoxy- quinolin- 3- yl)- 4- dimethylamino- 2- (3- fluorophenyl)- 1- phenyl- butan- 2- ol (R207910)
IBA
09/2007
1
Matrix Metalloproteinase 9 (Gelatinase B)
IBA
11/2006
1
Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
IBA
09/2005
1
Enzymes
IBA
08/2005
1
Aerosols
IBA
03/2004
1
Interleukin-10 (Interleukin 10)
IBA
12/2002
1
Interleukin-12 (IL 12)
IBA
02/2002
1
adjuvant P40 (P 40)
IBA
02/2002