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Hiroshi Onuma Selected Research

Resistin

10/2015Metabolic status and resistin in chronic schizophrenia over a 2-year period with continuous atypical antipsychotics.
1/2010A at single nucleotide polymorphism-358 is required for G at -420 to confer the highest plasma resistin in the general Japanese population.
9/2009PPARgamma Pro12Ala Pro/Pro and resistin SNP-420 G/G genotypes are synergistically associated with plasma resistin in the Japanese general population.
1/2009A pilot study suggests that the G/G genotype of resistin single nucleotide polymorphism at -420 may be an independent predictor of a reduction in fasting plasma glucose and insulin resistance by pioglitazone in type 2 diabetes.
8/2008[Role of resistin in insulin resistance].
7/2008Serum resistin is positively correlated with the accumulation of metabolic syndrome factors in type 2 diabetes.
2/2008Serum resistin is reduced by glucose and meal loading in healthy human subjects.
6/2007Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population.
5/2007Serum resistin level is associated with insulin sensitivity in Japanese patients with type 2 diabetes mellitus.
4/2007Serum resistin is associated with the severity of microangiopathies in type 2 diabetes.
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Hiroshi Onuma Research Topics

Disease

20Insulin Resistance
01/2015 - 03/2002
12Breast Neoplasms (Breast Cancer)
01/2014 - 01/2009
8Neoplasms (Cancer)
08/2014 - 11/2010
5Type 2 Diabetes Mellitus (MODY)
09/2014 - 10/2004
3Hypertension (High Blood Pressure)
07/2008 - 09/2003
3Obesity
07/2008 - 09/2003
2Hyperglycemia
01/2015 - 05/2007
2Hypersensitivity (Allergy)
09/2014 - 02/2008
2Hepatocellular Carcinoma (Hepatoma)
01/2009 - 12/2005
1Schizophrenia (Dementia Praecox)
10/2015
1Prediabetic State (Prediabetes)
01/2015
1Periodontitis
01/2015
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
09/2014
1Colorectal Neoplasms (Colorectal Cancer)
06/2014
1Edema
06/2014
1Body Weight (Weight, Body)
02/2014
1Cardiovascular Diseases (Cardiovascular Disease)
10/2011
1Atherosclerosis
07/2008
1Diabetic Neuropathies (Diabetic Neuropathy)
02/2008
1Hypotension (Low Blood Pressure)
06/2007
1Diabetic Angiopathies (Diabetic Angiopathy)
04/2007
1Hyperlipidemias (Hyperlipidemia)
09/2003

Drug/Important Bio-Agent (IBA)

14ResistinIBA
10/2015 - 03/2002
10Insulin (Novolin)FDA Link
01/2015 - 03/2002
6HormonesIBA
01/2014 - 01/2009
4Glucose (Dextrose)FDA LinkGeneric
02/2014 - 05/2007
4Estrogens (Estrogen)FDA Link
01/2014 - 04/2009
3DNA (Deoxyribonucleic Acid)IBA
08/2014 - 01/2012
3AdiponectinIBA
06/2014 - 05/2007
3HDL CholesterolIBA
02/2014 - 06/2007
2Triglycerides (Triacylglycerol)IBA
12/2013 - 07/2008
2IsoflavonesIBA
07/2009 - 05/2009
2C-Reactive ProteinIBA
08/2008 - 06/2007
2Insulin Receptor Substrate ProteinsIBA
07/2008 - 11/2002
1Antipsychotic Agents (Antipsychotics)IBA
10/2015
1Blood Glucose (Blood Sugar)IBA
01/2015
1AutoantibodiesIBA
09/2014
1Environmental PollutantsIBA
08/2014
1Retinoid X Receptors (Retinoid X Receptor)IBA
06/2014
1DiureticsIBA
06/2014
1PPAR gammaIBA
06/2014
1Biological Markers (Surrogate Marker)IBA
06/2014
1CadmiumIBA
01/2014
1ORALIT (ORS)IBA
01/2014
1TeaIBA
01/2014
1AntibodiesIBA
04/2011
1AntigensIBA
04/2011
1Progesterone Receptors (Progesterone Receptor)IBA
11/2010
1Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA
01/2010
1Sex Hormone-Binding GlobulinIBA
01/2010
13 (or 17)-beta-hydroxysteroid dehydrogenaseIBA
01/2010
1Aromatase (CYP19)IBA
01/2010
1CytochromesIBA
01/2010
1MirexIBA
07/2009
1DDTIBA
07/2009
1nonachlorIBA
07/2009
1Hexachlorobenzene (HCB)IBA
07/2009
1o,p'-DDTIBA
07/2009
1beta-hexachlorocyclohexaneIBA
07/2009
1oxychlordaneIBA
07/2009
1Polychlorinated Biphenyls (PCBs)IBA
07/2009
1Dichlorodiphenyl Dichloroethylene (DDE)IBA
07/2009
1Estrogen ReceptorsIBA
05/2009
1Estrogen Receptor betaIBA
05/2009
1cytochrome P-450 CYP1B1 (CYP1B1)IBA
04/2009
1Cytochrome P-450 CYP1A1 (CYP1A1)IBA
04/2009
1Cytochrome P-450 CYP1A2 (CYP1A2)IBA
04/2009
1Epidermal Growth Factor (EGF)IBA
01/2009
15,10-methylenetetrahydrofolateIBA
01/2009
1OxidoreductasesIBA
01/2009
1Riboflavin (Vitamin B2)FDA LinkGeneric
01/2009
1Vitamin B 6IBA
01/2009
15-Methyltetrahydrofolate-Homocysteine S-Methyltransferase (Methyltetrahydrofolate Homocysteine Methyltransferase)IBA
01/2009
1Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
01/2009
1pioglitazone (Actos)FDA Link
01/2009
1EnzymesIBA
01/2009
1Folic Acid (Vitamin M)FDA LinkGeneric
01/2009
1Vitamin B Complex (B Vitamins)IBA
01/2009
1Mitogen-Activated Protein Kinase 8IBA
07/2008
1Serine (L-Serine)FDA Link
07/2008
1Phosphotransferases (Kinase)IBA
07/2008
1AdipokinesIBA
02/2008
1LeptinIBA
05/2007
1GlucocorticoidsIBA
12/2005
1Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA
12/2005
1Insulin ReceptorIBA
08/2005
1Sterol Esterase (Hormone-Sensitive Lipase)IBA
09/2003
1Type 3 Cyclic Nucleotide PhosphodiesterasesIBA
09/2003