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Lloyd J Old Selected Research

Antigens

01/2008Cancer-testis (CT) antigen expression in medulloblastoma.
12/2007Expression and purification of the cancer antigen SSX2: a potential cancer vaccine.
02/2007Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation.
02/2007Epitope clustering in regions undergoing efficient proteasomal processing defines immunodominant CTL regions of a tumor antigen.
02/2007Melanocyte differentiation antigen RAB38/NY-MEL-1 induces frequent antibody responses exclusively in melanoma patients.
01/2007Cancer/testis (CT) antigens are expressed in fetal ovary.
01/2007Expression of cancer-testis (CT) antigens in placenta.
09/2006Cancer-testis antigens: expression and correlation with survival in human urothelial carcinoma.
05/2006Striking immunodominance hierarchy of naturally occurring CD8+ and CD4+ T cell responses to tumor antigen NY-ESO-1.
01/2006Expression of synovial sarcoma X (SSX) antigens in epithelial ovarian cancer and identification of SSX-4 epitopes recognized by CD4+ T cells.
01/2006NY-ESO-1: review of an immunogenic tumor antigen.
01/2006Physical interaction of two cancer-testis antigens, MAGE-C1 (CT7) and NY-ESO-1 (CT6).
01/2006Generation of monoclonal antibodies to cancer/testis (CT) antigen CT10/MAGE-C2.
10/2005Serological identification of breast cancer-related antigens from a Saccharomyces cerevisiae surface display library.
10/2005Identification of B cell epitopes recognized by antibodies specific for the tumor antigen NY-ESO-1 in cancer patients with spontaneous immune responses.
08/2005CD4+ CD25+ regulatory T cells control the induction of antigen-specific CD4+ helper T cell responses in cancer patients.
08/2005Cancer/testis antigens, gametogenesis and cancer.
07/2005The cancer-testis antigens CT7 (MAGE-C1) and MAGE-A3/6 are commonly expressed in multiple myeloma and correlate with plasma-cell proliferation.
05/2005Identification of cancer/testis-antigen genes by massively parallel signature sequencing.
01/2005Identification of CT46/HORMAD1, an immunogenic cancer/testis antigen encoding a putative meiosis-related protein.
01/2005Humoral and cellular immune responses against the breast cancer antigen NY-BR-1: definition of two HLA-A2 restricted peptide epitopes.
12/2004Immunohistochemical and molecular analysis of human melanomas for expression of the human cancer-testis antigens NY-ESO-1 and LAGE-1.
11/2004Real-Time, label-free monitoring of tumor antigen and serum antibody interactions.
11/2004Identification of the gonad-specific anion transporter SLCO6A1 as a cancer/testis (CT) antigen expressed in human lung cancer.
11/2004Cancer/testis antigen expression and autologous humoral immunity to NY-ESO-1 in gastric cancer.
10/2004SCP-1 cancer/testis antigen is a prognostic indicator and a candidate target for immunotherapy in epithelial ovarian cancer.
07/2004The humoral immune response to head and neck cancer antigens as defined by the serological analysis of tumor antigens by recombinant cDNA expression cloning.
03/2004[Expression of multiple cancer-testis antigen genes in non-small cell lung cancer treated by chemotherapy prior surgery]
10/2003Antigen-specific immunity in neuroblastoma patients: antibody and T-cell recognition of NY-ESO-1 tumor antigen.
10/2003SSX antigens as tumor vaccine targets in human sarcoma.
10/2003Expression of cancer/testis (CT) antigens in lung cancer.
09/2003NY-ESO-1 and LAGE-1 cancer-testis antigens are potential targets for immunotherapy in epithelial ovarian cancer.
10/2002Serological identification of antigens associated with renal cell carcinoma.
10/2002Cancer/testis antigens: an expanding family of targets for cancer immunotherapy.
08/2002Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations.
08/2002Urine antibody against human cancer antigen NY-ESO-1.
06/2002Identification of tumor-restricted antigens NY-BR-1, SCP-1, and a new cancer/testis-like antigen NW-BR-3 by serological screening of a testicular library with breast cancer serum.
06/2002Identification of breast cancer-restricted antigens by antibody screening of SKBR3 cDNA library using a preselected patient's serum.
02/2002MAGE antigen expression in monophasic and biphasic synovial sarcoma.

Articles by Research Topic

Disease

26Neoplasms (Cancer)
12/2007 - 06/2002
21Testicular Neoplasms (Testicular Cancer)
01/2008 - 04/2002
6Ovarian Neoplasms (Ovarian Cancer)
08/2008 - 09/2003
5Breast Neoplasms (Breast Cancer)
10/2005 - 06/2002
3Melanoma (Melanoma, Malignant)
02/2007 - 12/2004
3Carcinoma (Carcinomatosis)
09/2006 - 06/2005
2Multiple Myeloma
02/2007 - 07/2005
2Renal Cell Carcinoma (Grawitz Tumor)
01/2007 - 10/2002
2Colorectal Neoplasms (Colorectal Cancer)
09/2006 - 04/2003
2Synovial Sarcoma (Synovioma)
01/2006 - 02/2002
2Lung Neoplasms (Lung Cancer)
11/2004 - 10/2003
1Medulloblastoma
01/2008
1Vaccinia
09/2006
1Fowlpox
09/2006
1Stomach Neoplasms (Stomach Cancer)
11/2004
1Kidney Neoplasms (Kidney Cancer)
08/2004
1Head and Neck Neoplasms (Head and Neck Cancer)
07/2004
1Small Cell Carcinoma
03/2004
1Urinary Bladder Neoplasms (Bladder Cancer)
12/2003
1Neuroblastoma
10/2003
1Sarcoma (Soft Tissue Sarcoma)
10/2003
1Prostatic Neoplasms (Prostate Cancer)
07/2003

Drug/Important Bio-Agent (IBA)

39AntigensIBA
01/2008 - 02/2002
4Messenger RNA (mRNA)IBA
10/2005 - 04/2002
3HLA-A2 Antigen (HLA A2 Antigen)IBA
01/2007 - 09/2002
2T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
08/2008 - 12/2003
2EpitopesIBA
01/2006 - 01/2005
2AntibodiesIBA
10/2005 - 06/2005
2Epidermal Growth Factor Receptor (EGF Receptor)IBA
09/2005 - 01/2003
2SCP 1IBA
10/2004 - 06/2002
1monoclonal antibody Hu3S193IBA
06/2007
1Lewis Y antigenIBA
06/2007
1Interleukin-2 (IL2)IBA
01/2007
1pullulanIBA
01/2007
1CholesterolIBA
01/2007
1PeptidesIBA
01/2007
1VaccinesIBA
09/2006
1PerforinIBA
09/2006
1flt3 ligand protein (flt3 ligand)IBA
09/2006
1CD40 Ligand (CD40L)IBA
09/2006
1Glycoproteins (Glycoprotein)IBA
01/2006
1Monoclonal AntibodiesIBA
01/2006
1B-Lymphocyte Epitopes (B-Cell Epitope)IBA
10/2005
1Phosphotransferases (Kinase)IBA
10/2005
1monoclonal antibody 806IBA
09/2005
1monoclonal antibody KM871IBA
02/2005
1HLA-DPB1 (HLA DPB1)IBA
11/2004
1Neoplasm Antigens (Tumor Antigens)IBA
07/2004
1Complementary DNA (cDNA)IBA
07/2004
1sibrotuzumabIBA
05/2003

Therapy/Procedure

7Immunotherapy
01/2006 - 10/2002
2Heterologous Transplantation (Xenotransplantation)
09/2005 - 08/2003
1Stem Cell Transplantation
02/2007
1Radioimmunotherapy
08/2004
1Drug Therapy (Chemotherapy)
03/2004
1Combination Drug Therapy (Combination Chemotherapy)
04/2003