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Naoki Okumura Selected Research

Y 27632

9/2015Effect of the Rho Kinase Inhibitor Y-27632 on Corneal Endothelial Wound Healing.
4/2013The ROCK inhibitor eye drop accelerates corneal endothelium wound healing.
1/2012A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma.
7/2011Enhancement of corneal endothelium wound healing by Rho-associated kinase (ROCK) inhibitor eye drops.

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Naoki Okumura Research Topics

Disease

11Neoplasms (Cancer)
10/2015 - 05/2002
8Neoplasm Metastasis (Metastasis)
10/2015 - 11/2002
8Colorectal Neoplasms (Colorectal Cancer)
10/2015 - 11/2002
4Stomach Neoplasms (Stomach Cancer)
12/2013 - 01/2011
3Breast Neoplasms (Breast Cancer)
10/2015 - 08/2002
3Myocardial Infarction
01/2013 - 01/2012
2Corneal Edema
09/2015 - 04/2013
2Edema
11/2014 - 04/2013
2Rectal Neoplasms (Rectal Cancer)
01/2013 - 10/2004
1Glaucoma
11/2015
1Ocular Hypertension (Glaucoma, Suspect)
11/2015
1Cataract (Cataracts)
09/2015
1Infection
02/2015
1Hemorrhage
02/2015
1Wound Infection (Wound Infections)
02/2015
1Appendicitis
01/2015
1Herpes Zoster
10/2014
1Hypertension (High Blood Pressure)
03/2014
1Sigmoid Neoplasms
01/2014
1Iron-Deficiency Anemia (Anemia, Iron Deficiency)
12/2013
1Anemia
12/2013
1Colonic Neoplasms (Colon Cancer)
07/2013
1Fanconi Anemia (Fanconi's Anemia)
07/2013
1Cardiovascular Diseases (Cardiovascular Disease)
01/2013
1Proliferative Vitreoretinopathy
10/2012
1Diabetic Retinopathy (Retinopathy, Diabetic)
10/2012
1Eye Diseases (Eye Disease)
10/2012
1Acute Coronary Syndrome
01/2012
1Stroke (Strokes)
01/2012
1Hypotension (Low Blood Pressure)
01/2012
1Kidney Diseases (Kidney Disease)
01/2012
1Heart Failure
01/2012
1Acute Kidney Injury (Acute Renal Failure)
01/2012
1Death (Near-Death Experience)
01/2012
1Cicatrix (Scar)
01/2012
1Coronary Artery Disease (Coronary Atherosclerosis)
01/2012
1Myocardial Ischemia (Ischemic Heart Diseases)
01/2012
1Granuloma
07/2011
1Wounds and Injuries (Trauma)
07/2011
1Atherosclerotic Plaque (Atheroma)
01/2011
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2009
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2008
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
09/2008
1Allergic Conjunctivitis (Giant Papillary Conjunctivitis)
10/2006
1Hepatocellular Carcinoma (Hepatoma)
06/2006
1Liver Diseases (Liver Disease)
06/2006
1Pain (Aches)
10/2004

Drug/Important Bio-Agent (IBA)

4Y 27632IBA
09/2015 - 07/2011
3Ophthalmic Solutions (Eye Drops)IBA
09/2015 - 04/2013
2Epidermal Growth Factor Receptor (EGF Receptor)IBA
01/2014 - 09/2008
2DNA (Deoxyribonucleic Acid)IBA
07/2013 - 09/2008
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2012 - 06/2006
2Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2010 - 06/2006
2Estrogen Receptor alphaIBA
08/2002 - 05/2002
1Protein Kinases (Protein Kinase)IBA
11/2015
1Vitamin K 3 (Menadione)FDA Link
10/2015
1Ethanol (Ethyl Alcohol)IBA
10/2015
1glucuronyl glucosamine glycan sulfate (Vessel)IBA
10/2015
1Adenosine Triphosphatases (ATPase)IBA
10/2014
1Antihypertensive Agents (Antihypertensives)IBA
03/2014
1panitumumab (Vectibix)FDA Link
01/2014
1IronIBA
12/2013
1Fluorouracil (Carac)FDA LinkGeneric
07/2013
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
07/2013
1oxaliplatin (Eloxatin)FDA LinkGeneric
07/2013
1LeptinIBA
01/2013
1AdipokinesIBA
01/2013
1AdiponectinIBA
01/2013
1pioglitazone (Actos)FDA Link
10/2012
1Retinaldehyde (Retinal)IBA
10/2012
1rho-Associated KinasesIBA
01/2012
1human NPPA protein (carperitide)IBA
01/2012
1CholesterolIBA
07/2011
1HDL CholesterolIBA
01/2011
1LDL CholesterolIBA
01/2011
1Glucosamine (Dona)IBA
12/2010
1Heparitin Sulfate (Heparan Sulfate)IBA
12/2010
1Adenocarcinoma of lungIBA
01/2009
1O-deacetyl platelet activating factorIBA
10/2006
1Platelet Activating FactorIBA
10/2006
1Phosphotransferases (Kinase)IBA
06/2006
1Tyrosine (L-Tyrosine)FDA Link
06/2006
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
06/2006
1Tumor Suppressor Protein p53IBA
08/2002

Therapy/Procedure

8Drug Therapy (Chemotherapy)
10/2015 - 11/2002
5Hepatectomy
10/2015 - 01/2010
2Gastrectomy
12/2013 - 06/2013
2Intra-Arterial Infusions
10/2004 - 11/2002
1Gastrostomy
02/2015
1Blood Transfusion (Blood Transfusions)
02/2015
1Appendectomy
01/2015
1Lymph Node Excision (Lymph Node Dissection)
01/2013
1Suture Techniques
01/2013
1Stents
01/2013
1Drug-Eluting Stents
01/2013
1Patient Readmission
01/2012
1Heterologous Transplantation (Xenotransplantation)
01/2009
1Cryosurgery
05/2007
1Radiotherapy
10/2004
1Colectomy
11/2002